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ChemicalBook >> CAS DataBase List >> Trimethyl phosphonoacetate

Trimethyl phosphonoacetate

Trimethyl phosphonoacetate price.
  • $5 - $2200
  • Product name: Trimethyl phosphonoacetate
  • CAS: 5927-18-4
  • MF: C5H11O5P
  • MW: 182.11
  • EINECS:227-663-0
  • MDL Number:MFCD00008452
  • Synonyms:TriMethyl phosphonoacetate, 98% 25GR;Dimethylphosphonoacetic Acid Methyl Ester Methyl Dimethylphosphonoacetate Phosphonoacetic Acid Trimethyl Ester;TriMethyl phosphonoacetat;Aceticacid, 2-(diMethoxyphosphinyl)-, Methyl ester;Dibenzyloxyphosphoiyl three Methyl acetate;(Carboxymethyl)phosphonic acid trimethyl ester;Dimethyl methoxycarbonylmethylphosphonate~Phosphonoacetic acid trimethyl ester;trimethylacetyl phosphate
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  • ManufacturerAK Scientific
  • Product numberJ93888
  • Product descriptionTrimethyl phosphonoacetate 95%
  • Packaging5g
  • Price$12
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberM992
  • Product descriptionTrimethyl Phosphonoacetate
  • Packaging5g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberM992
  • Product descriptionTrimethyl phosphonoacetate 98%(GC)
  • Packaging5g
  • Price$16
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ93888
  • Product descriptionTrimethyl phosphonoacetate 95%
  • Packaging25g
  • Price$17
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20336
  • Product descriptionTrimethyl phosphonoacetate 99%(GC)
  • Packaging5g
  • Price$20
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20336
  • Product descriptionTrimethyl phosphonoacetate 99%(GC)
  • Packaging100g
  • Price$77
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20336
  • Product descriptionTrimethyl phosphonoacetate 99%(GC)
  • Packaging25g
  • Price$30
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ93888
  • Product descriptionTrimethyl phosphonoacetate 95%
  • Packaging100g
  • Price$41
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ93888
  • Product descriptionTrimethyl phosphonoacetate 95%
  • Packaging500g
  • Price$94
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ93888
  • Product descriptionTrimethyl phosphonoacetate 95%
  • Packaging1kg
  • Price$130
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberM992
  • Product descriptionTrimethyl phosphonoacetate 98%(GC)
  • Packaging500g
  • Price$127
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberM992
  • Product descriptionTrimethyl phosphonoacetate 98%(GC)
  • Packaging100g
  • Price$56
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberM992
  • Product descriptionTrimethyl phosphonoacetate 98%(GC)
  • Packaging25g
  • Price$23
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberM992
  • Product descriptionTrimethyl Phosphonoacetate
  • Packaging1kg
  • Price$334
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20336
  • Product descriptionTrimethyl phosphonoacetate 99%(GC)
  • Packaging500g
  • Price$170
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberM992
  • Product descriptionTrimethyl phosphonoacetate 98%(GC)
  • Packaging1kg
  • Price$178
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J93888 Trimethyl phosphonoacetate 95% 5g $12 2026-06-04 Buy
AK Scientific M992 Trimethyl Phosphonoacetate 5g $14 2021-12-16 Buy
AK Scientific M992 Trimethyl phosphonoacetate 98%(GC) 5g $16 2026-06-04 Buy
AK Scientific J93888 Trimethyl phosphonoacetate 95% 25g $17 2026-06-04 Buy
AK Scientific J20336 Trimethyl phosphonoacetate 99%(GC) 5g $20 2026-06-04 Buy
AK Scientific J20336 Trimethyl phosphonoacetate 99%(GC) 100g $77 2026-06-04 Buy
AK Scientific J20336 Trimethyl phosphonoacetate 99%(GC) 25g $30 2026-06-04 Buy
AK Scientific J93888 Trimethyl phosphonoacetate 95% 100g $41 2026-06-04 Buy
AK Scientific J93888 Trimethyl phosphonoacetate 95% 500g $94 2026-06-04 Buy
AK Scientific J93888 Trimethyl phosphonoacetate 95% 1kg $130 2026-06-04 Buy
AK Scientific M992 Trimethyl phosphonoacetate 98%(GC) 500g $127 2026-06-04 Buy
AK Scientific M992 Trimethyl phosphonoacetate 98%(GC) 100g $56 2026-06-04 Buy
AK Scientific M992 Trimethyl phosphonoacetate 98%(GC) 25g $23 2026-06-04 Buy
AK Scientific M992 Trimethyl Phosphonoacetate 1kg $334 2021-12-16 Buy
AK Scientific J20336 Trimethyl phosphonoacetate 99%(GC) 500g $170 2026-06-04 Buy
AK Scientific M992 Trimethyl phosphonoacetate 98%(GC) 1kg $178 2026-06-04 Buy

Properties

Melting point :242 °C
Boiling point :118 °C0.85 mm Hg(lit.)
Density :1.125 g/mL at 25 °C(lit.)
refractive index :n20/D 1.437(lit.)
Flash point :>230 °F
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
form :Liquid
Specific Gravity :approximate 1.265g/ml (20℃)
color :Clear colorless to light yellow
Water Solubility :Slightly miscible with water.
BRN :1865177
InChI :1S/C5H11O5P/c1-8-5(6)4-11(7,9-2)10-3/h4H2,1-3H3
InChIKey :SIGOIUCRXKUEIG-UHFFFAOYSA-N
SMILES :COC(=O)CP(=O)(OC)OC
LogP :-0.680 (est)
CAS DataBase Reference :5927-18-4(CAS DataBase Reference)
NIST Chemistry Reference :Trimethyl phosphonoacetate(5927-18-4)
EPA Substance Registry System :Acetic acid, (dimethoxyphosphinyl)-, methyl ester (5927-18-4)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.

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