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ChemicalBook >> CAS DataBase List >> 6-O-Benzylguanine

6-O-Benzylguanine

$5 - $4010
Product name: 6-O-Benzylguanine
CAS: 19916-73-5
MF: C12H11N5O
MW: 241.25
EINECS:1592732-453-0
MDL Number:MFCD00269931
Synonyms:O(sup 6)benzylguanidine;2-Amino-6-(benzyloxy)-9H-purine;6-(Benzyloxy)-1H-purin-2-amine;6-(PhenylMethoxy)-9H-purin-2-aMine;NSC 637037;6-oxo -benzylguanine;6-O-Benzylguanine(O6BG);9H-Purin-2-amine,6-(phenylmethoxy)-

Price108 Properties Safety Information Description

108 prices

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Brand

aablocks
AccelPharmtech
AK Scientific
Alichem
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Apolloscientific
Arctom
AstaTech
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
CSNpharm
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
Sigma-Aldrich
SynQuest Laboratories
TCI Chemical
Thermo Scientific Chemicals
TRC
Usbiological

Package

10mM*1mLinDMSO(Solid+Solvent)
5mg
10mg
25mg
100mg
10mM*1mLinDMSO(Solution)
50MG
250mg
500mg
1G
5g
10g
25g
50g
100g
0.1kg
0.25kg
250g
0.5kg
2.5kg
10mM(in1mLDMSO)
500g

Manufactureraablocks
Product numberAA002BUP
Product description6-(Phenylmethoxy)-9H-purin-2-amine 98%
Packaging25g
Price$8
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA002BUP
Product description6-(Phenylmethoxy)-9H-purin-2-amine 98%
Packaging10g
Price$7
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA002BUP
Product description6-(Phenylmethoxy)-9H-purin-2-amine 98%
Packaging5g
Price$5
Updated2026-05-28
Buy

ManufacturerAccelPharmtech
Product numberC1238
Product description6-O-Benzylguanine 97.00%
Packaging1G
Price$1940
Updated2021-12-16
Buy

ManufacturerAccelPharmtech
Product numberC1238
Product description6-O-Benzylguanine 97.00%
Packaging5G
Price$2180
Updated2021-12-16
Buy

ManufacturerAccelPharmtech
Product numberC1238
Product description6-O-Benzylguanine 97.00%
Packaging25G
Price$4010
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberJ10132
Product description6-O-Benzylguanine >98%(HPLC),powder
Packaging5g
Price$245
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberH350
Product description6-O-Benzylguanine 98%(HPLC)
Packaging100g
Price$187
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberJ92255
Product description6-O-Benzylguanine 95%
Packaging100g
Price$140
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberJ92255
Product description6-O-Benzylguanine
Packaging1g
Price$10
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberH350
Product description6-O-Benzylguanine 98%(HPLC)
Packaging1g
Price$16
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberJ92255
Product description6-O-Benzylguanine 95%
Packaging5g
Price$18
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberJ92255
Product description6-O-Benzylguanine 95%
Packaging1g
Price$12
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberH350
Product description6-O-Benzylguanine 98%(HPLC)
Packaging5g
Price$24
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberJ10132
Product description6-O-Benzylguanine >98%(HPLC),powder
Packaging250mg
Price$41
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberJ92255
Product description6-O-Benzylguanine
Packaging25g
Price$49
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA002BUP	6-(Phenylmethoxy)-9H-purin-2-amine 98%	25g	$8	2026-05-28	Buy
aablocks	AA002BUP	6-(Phenylmethoxy)-9H-purin-2-amine 98%	10g	$7	2026-05-28	Buy
aablocks	AA002BUP	6-(Phenylmethoxy)-9H-purin-2-amine 98%	5g	$5	2026-05-28	Buy
AccelPharmtech	C1238	6-O-Benzylguanine 97.00%	1G	$1940	2021-12-16	Buy
AccelPharmtech	C1238	6-O-Benzylguanine 97.00%	5G	$2180	2021-12-16	Buy
AccelPharmtech	C1238	6-O-Benzylguanine 97.00%	25G	$4010	2021-12-16	Buy
AK Scientific	J10132	6-O-Benzylguanine >98%(HPLC),powder	5g	$245	2026-06-04	Buy
AK Scientific	H350	6-O-Benzylguanine 98%(HPLC)	100g	$187	2026-06-04	Buy
AK Scientific	J92255	6-O-Benzylguanine 95%	100g	$140	2026-06-04	Buy
AK Scientific	J92255	6-O-Benzylguanine	1g	$10	2021-12-16	Buy
AK Scientific	H350	6-O-Benzylguanine 98%(HPLC)	1g	$16	2026-06-04	Buy
AK Scientific	J92255	6-O-Benzylguanine 95%	5g	$18	2026-06-04	Buy
AK Scientific	J92255	6-O-Benzylguanine 95%	1g	$12	2026-06-04	Buy
AK Scientific	H350	6-O-Benzylguanine 98%(HPLC)	5g	$24	2026-06-04	Buy
AK Scientific	J10132	6-O-Benzylguanine >98%(HPLC),powder	250mg	$41	2026-06-04	Buy
AK Scientific	J92255	6-O-Benzylguanine	25g	$49	2021-12-16	Buy

Next Last

Properties

Melting point :193(dec.)
Boiling point :459.3±55.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :methanol: 20 mg/mL
form :solid
pka :7.47±0.20(Predicted)
color :Off-White to Light Yellow
InChI :InChI=1S/C12H11N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H3,13,14,15,16,17)
InChIKey :KRWMERLEINMZFT-UHFFFAOYSA-N
SMILES :N1C2C(=NC(N)=NC=2OCC2=CC=CC=C2)NC=1
CAS DataBase Reference :19916-73-5(CAS DataBase Reference)

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

O6-Alkylguanine-DNA alkyltransferase (AGT, also known as methylguanine DNA methyltransferase, or MGMT) is a DNA repair protein that directly removes alkyl groups located on the O6-position of guanine from DNA, restoring DNA integrity in a single step. In the process, AGT is alkylated and irreversibly inactivated. O6-Benzylguanine is a guanine analog with antineoplastic activity. It serves as a pseudosubstrate for AGT, transferring a benzyl moiety to the active site cysteine of the enzyme. This leads to irreversible inactivation, with 40% reduction in alkyltransferase activity of recombinant human AGT achieved at 0.06 μM. O6-Benzylguanine is effective in vivo as well as in vitro. Inactivation of AGT increases the chemotherapeutic effectiveness of chloroethylating and methylating agents.

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Suppliers and manufacturers

Hebei Yanxi Chemical Co., Ltd.

$1.00
6-O-Benzylguanine CAS:19916-73-5

Hebei Chuanghai Biotechnology Co., Ltd

6-O-Benzylguanine CAS:19916-73-5

Henan Fengda Chemical Co., Ltd

$1.00
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airuikechemical co., ltd.

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Hebei Zhuanglai Chemical Trading Co.,Ltd

$150.00
6-O-Benzylguanine CAS:19916-73-5

career henan chemical co

$100.00
6-O-Benzylguanine CAS:19916-73-5

Capot Chemical Co.,Ltd.

ATK CHEMICAL COMPANY LIMITED

Zhejiang ZETian Fine Chemicals Co. LTD

Xiamen AmoyChem Co., Ltd

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6-O-Benzylguanine

Properties

Safety Information

Description

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