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ChemicalBook >> CAS DataBase List >> Ripasudil hydrochloride dihydrate

Ripasudil hydrochloride dihydrate

Ripasudil hydrochloride dihydrate price.
  • $14 - $3791
  • Product name: Ripasudil hydrochloride dihydrate
  • CAS: 887375-67-9
  • MF: C15H21ClFN3O3S
  • MW: 377.86
  • EINECS:
  • MDL Number:MFCD26960897
  • Synonyms:K-115 HCL;Ripasudil free base;RipasudilHCl Hydrate;K115 HCl Dihydrate;(2S)-1-[(4-Fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-1H-1,4-diazepine monohydrochloride dihydrate;K-115 (HCl H2O);Ripasudil HCl Dihydrate;K115 HCL 2H2O
75 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 10mM(1mLinDMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mM*1mLinDMSO
  • 25mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00GU13
  • Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
  • Packaging50mg
  • Price$83
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU13
  • Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
  • Packaging100mg
  • Price$128
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU13
  • Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
  • Packaging250mg
  • Price$237
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU13
  • Product descriptionRipasudil (K-115) hydrochloride dihydrate 95%
  • Packaging1g
  • Price$829
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU13
  • Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
  • Packaging25mg
  • Price$49
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU13
  • Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
  • Packaging10mg
  • Price$31
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU13
  • Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
  • Packaging5mg
  • Price$21
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU13
  • Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
  • Packaging2mg
  • Price$17
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GU13
  • Product descriptionRipasudil (K-115) hydrochloride dihydrate 98%
  • Packaging1mg
  • Price$14
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT98404
  • Product descriptionRipasudil 98%
  • Packaging25MG
  • Price$100
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT98404
  • Product descriptionRipasudil 98%
  • Packaging25MG
  • Price$100
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT98404
  • Product descriptionRipasudil 98%
  • Packaging100MG
  • Price$190
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT98404
  • Product descriptionRipasudil 98%
  • Packaging100MG
  • Price$190
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number3757AH
  • Product descriptionK-115
  • Packaging5mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130094
  • Product descriptionK-115HydrochlorideDihydrate 98+%
  • Packaging25mg
  • Price$242
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130094
  • Product descriptionK-115HydrochlorideDihydrate 98+%
  • Packaging10mg
  • Price$186
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00GU13 Ripasudil (K-115) hydrochloride dihydrate 98% 50mg $83 2026-05-28 Buy
aablocks AA00GU13 Ripasudil (K-115) hydrochloride dihydrate 98% 100mg $128 2026-05-28 Buy
aablocks AA00GU13 Ripasudil (K-115) hydrochloride dihydrate 98% 250mg $237 2026-05-28 Buy
aablocks AA00GU13 Ripasudil (K-115) hydrochloride dihydrate 95% 1g $829 2026-05-28 Buy
aablocks AA00GU13 Ripasudil (K-115) hydrochloride dihydrate 98% 25mg $49 2026-05-28 Buy
aablocks AA00GU13 Ripasudil (K-115) hydrochloride dihydrate 98% 10mg $31 2026-05-28 Buy
aablocks AA00GU13 Ripasudil (K-115) hydrochloride dihydrate 98% 5mg $21 2026-05-28 Buy
aablocks AA00GU13 Ripasudil (K-115) hydrochloride dihydrate 98% 2mg $17 2026-05-28 Buy
aablocks AA00GU13 Ripasudil (K-115) hydrochloride dihydrate 98% 1mg $14 2026-05-28 Buy
ACHEMBLOCK T98404 Ripasudil 98% 25MG $100 2026-05-25 Buy
ACHEMBLOCK T98404 Ripasudil 98% 25MG $100 2026-05-27 Buy
ACHEMBLOCK T98404 Ripasudil 98% 100MG $190 2026-05-25 Buy
ACHEMBLOCK T98404 Ripasudil 98% 100MG $190 2026-05-27 Buy
AK Scientific 3757AH K-115 5mg $200 2021-12-16 Buy
Ambeed A130094 K-115HydrochlorideDihydrate 98+% 25mg $242 2021-12-16 Buy
Ambeed A130094 K-115HydrochlorideDihydrate 98+% 10mg $186 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :insoluble in EtOH; ≥123.2 mg/mL in DMSO; ≥41.7 mg/mL in H2O
form :solid
color :White to off-white
Stability :Hygroscopic

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ripasudil hydrochloride hydrate (Glanatec®) was approved in Japan in 2014 for the treatment of glaucoma and ocular hypertension. Originally discovered by D. Western Therapeutics Institute, Inc. and licensed by the Kowa Company, Ltd, ripasudil functions as a selective Rho-kinase inhibitor and reduces intraocular pressure by stimulation of aqueous humour drainage of the trabecular meshwork. While this recent approval allows for use of ripasudil as a twice-daily monotherapy treatment when other drugs cannot be used or are not effective, clinical trials using ripasudil as a combination therapy with other glaucoma drugs have shown promising results in the treatment of primary open-angle glaucoma or ocular hypertension. Currently, the Kowa Company is also pursuing trials focused on the use of ripasudil for the treatment of diabetic retinopathy and diabetic macular edema.

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