リパスジル塩酸塩水和物
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- ￥561600
- 化學(xué)名: リパスジル塩酸塩水和物
- 英語(yǔ)名: Ripasudil hydrochloride dihydrate
- 別名:リパスジル塩酸塩水和物;グラナテック;リパスジル;4-フルオロ-5-[[(2S)-2-メチルヘキサヒドロ-1H-1,4-ジアゼピン-1-イル]スルホニル]イソキノリン?塩酸塩?2水和物;4-フルオロ-5-[[(2S)-2β-メチルヘキサヒドロ-1H-1,4-ジアゼピン-1-イル]スルホニル]イソキノリン?塩酸塩?2水和物
- CAS番號(hào): 887375-67-9
- 分子式: C15H21ClFN3O3S
- 分子量: 377.86
- EINECS:
- MDL Number:MFCD26960897
1物価
選択條件：
ブランド
- 富士フイルム和光純薬株式會(huì)社(wako)
パッケージ
- 100mg
- 生産者富士フイルム和光純薬株式會(huì)社(wako)
- 製品番號(hào)W01COBQJ-0620
- 製品説明
- 英語(yǔ)製品説明4-Fluoro-5-[(2S)-2-methyl-1,4-diazepane-1-sulfonyl]isoquinoline dihydrate hydrochloride
- 包裝単位100mg
- 価格￥561600
- 更新しました2020-09-21
- 購(gòu)入
| 生産者 | 製品番號(hào) | 製品説明 | 包裝単位 | 価格 | 更新時(shí)間 | 購(gòu)入 |
|---|---|---|---|---|---|---|
| 富士フイルム和光純薬株式會(huì)社(wako) | W01COBQJ-0620 | 4-Fluoro-5-[(2S)-2-methyl-1,4-diazepane-1-sulfonyl]isoquinoline dihydrate hydrochloride |
100mg | ￥561600 | 2020-09-21 | 購(gòu)入 |
プロパティ
貯蔵溫度 :Store at -20°C
溶解性 :insoluble in EtOH; ≥123.2 mg/mL in DMSO; ≥41.7 mg/mL in H2O
外見(jiàn) :solid
色 :White to off-white
安定性： :Hygroscopic
溶解性 :insoluble in EtOH; ≥123.2 mg/mL in DMSO; ≥41.7 mg/mL in H2O
外見(jiàn) :solid
色 :White to off-white
安定性： :Hygroscopic
安全情報(bào)
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説明
Ripasudil hydrochloride hydrate (Glanatec®) was approved in Japan in 2014 for the treatment of glaucoma and ocular hypertension. Originally discovered by D. Western Therapeutics Institute, Inc. and licensed by the Kowa Company, Ltd, ripasudil functions as a selective Rho-kinase inhibitor and reduces intraocular pressure by stimulation of aqueous humour drainage of the trabecular meshwork. While this recent approval allows for use of ripasudil as a twice-daily monotherapy treatment when other drugs cannot be used or are not effective, clinical trials using ripasudil as a combination therapy with other glaucoma drugs have shown promising results in the treatment of primary open-angle glaucoma or ocular hypertension. Currently, the Kowa Company is also pursuing trials focused on the use of ripasudil for the treatment of diabetic retinopathy and diabetic macular edema.関連商品価格
- 4-フルオロ-5-{[(2S)-2-メチル-1,4-ジアゼパン-1-イル]スルホニル}イソキノリン
￥18500-680500 - リオシグアット
￥54000-784800