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ChemicalBook >> CAS DataBase List >> 5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione

5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione

$44 - $2200
Product name: 5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione
CAS: 958852-01-2
MF: C18H11N3O2S
MW: 333.36
EINECS:
MDL Number:MFCD18074517
Synonyms:5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione;GSK 1059615;GSK 1059615 SodiuM Salt Hydrate;SK1059615;(5Z)-5-[[4-(4-pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione sodium salt hydrate;GSK-615;GSK1059615;GSK 1059615; GSK-1059615;GSK 1059615;GSK-1059615

Price63 Properties Safety Information Description

63 prices

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aablocks
ACHEMBLOCK
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

2MG
5mg
10mg
1mg
50
10
25mg
50mg
100mg
250mg
1g
10 mg
50 mg

Manufactureraablocks
Product numberAA005WVA
Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
Packaging10mg
Price$98
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005WVA
Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
Packaging25mg
Price$179
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005WVA
Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
Packaging50mg
Price$283
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005WVA
Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
Packaging100mg
Price$417
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005WVA
Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
Packaging5mg
Price$69
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA005WVA
Product description(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
Packaging1mg
Price$44
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberP50916
Product descriptionGSK1059615 98%
Packaging2MG
Price$65
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberP50916
Product descriptionGSK1059615 98%
Packaging25MG
Price$395
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberP50916
Product descriptionGSK1059615 98%
Packaging100MG
Price$1150
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberP50916
Product descriptionGSK1059615 98%
Packaging5MG
Price$130
Updated2026-05-27
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000877
Product descriptionGSK-1059615 95.00%
Packaging100MG
Price$1871.1
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000877
Product descriptionGSK-1059615 95.00%
Packaging10MG
Price$739.2
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB2176
Product descriptionGSK1059615
Packaging50mg
Price$450
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB2176
Product descriptionGSK1059615
Packaging50mg
Price$495
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB2176
Product descriptionGSK1059615
Packaging10mg
Price$115
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB2176
Product descriptionGSK1059615
Packaging10mg
Price$115
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA005WVA	(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione	10mg	$98	2026-05-28	Buy
aablocks	AA005WVA	(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione	25mg	$179	2026-05-28	Buy
aablocks	AA005WVA	(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione	50mg	$283	2026-05-28	Buy
aablocks	AA005WVA	(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione	100mg	$417	2026-05-28	Buy
aablocks	AA005WVA	(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione	5mg	$69	2026-05-28	Buy
aablocks	AA005WVA	(5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione	1mg	$44	2026-05-28	Buy
ACHEMBLOCK	P50916	GSK1059615 98%	2MG	$65	2026-05-27	Buy
ACHEMBLOCK	P50916	GSK1059615 98%	25MG	$395	2026-05-27	Buy
ACHEMBLOCK	P50916	GSK1059615 98%	100MG	$1150	2026-05-27	Buy
ACHEMBLOCK	P50916	GSK1059615 98%	5MG	$130	2026-05-27	Buy
American Custom Chemicals Corporation	KIN0000877	GSK-1059615 95.00%	100MG	$1871.1	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000877	GSK-1059615 95.00%	10MG	$739.2	2021-12-16	Buy
ApexBio Technology	B2176	GSK1059615	50mg	$450	2026-05-06	Buy
ApexBio Technology	B2176	GSK1059615	50mg	$495	2021-12-16	Buy
ApexBio Technology	B2176	GSK1059615	10mg	$115	2021-12-16	Buy
ApexBio Technology	B2176	GSK1059615	10mg	$115	2026-05-06	Buy

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Properties

Melting point :>290°C (dec.)
storage temp. :Store at +4°C
solubility :H2O: ≥8mg/mL
form :powder
color :yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PI 3-kinase α (PI3Kα) is a critical regulator of cell growth and transformation. Its signaling pathway is the most commonly mutated pathway in human cancers. GSK1059615 is a potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM) and the common activating mutants of p110α (E542K, E545K, and H1047R) found in cancer. It prevents proliferation in BT474 tumor xenografts and reduces MAPK signaling following twice daily dosing at 25 mg/kg.

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Suppliers and manufacturers

career henan chemical co

$950.00
5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione CAS:958852-01-2

TargetMol Chemicals Inc.

$61.00
GSK1059615 CAS:958852-01-2

ATK CHEMICAL COMPANY LIMITED

CONIER CHEM AND PHARMA LIMITED

Dideu Industries Group Limited

BOC Sciences

Zhejiang J&C Biological Technology Co.,Limited

changzhou huayang technology co., ltd

InvivoChem

Hangzhou MolCore BioPharmatech Co.,Ltd.

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5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers