Adapalene
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- $6 - $1504.5
- Product name: Adapalene
- CAS: 106685-40-9
- MF: C28H28O3
- MW: 412.52
- EINECS:620-513-9
- MDL Number:MFCD03106112
- Synonyms:ADAPALENE;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID;6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid;Differi;6-[4-Methoxy-3-(adamantan-1-yl)phenyl]-2-naphthalenecarboxylic acid;6-[3-(adaMantan-1-yl)-4-Methoxyphenyl]naphthalene-2-carboxylic acid;[1]6-[4-Methoxy-3-(tricyclo[3.3.1.1~3,7~]dec-1-yl)phenyl]naphthalene-2-carboxylic acid;p75(NTR)
125 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AstaTech
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM*1mLinDMSO(Solution)
- 10
- y0001119
- 100mg
- 50
- 200MG
- 250mg
- y0001121
- 0.25G
- 10mM(in1mLDMSO)
- 500mg
- 1g
- 2g
- 5g
- 10g
- 25g
- 10mM(in 1mL DMSO)
- 100 mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 2.02 mg
- Manufactureraablocks
- Product numberAA00388Z
- Product description6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid 99%
- Packaging250mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00388Z
- Product description6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid 99%
- Packaging1g
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00388Z
- Product description6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid 99%
- Packaging5g
- Price$95
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00388Z
- Product description6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid 99%
- Packaging25g
- Price$344
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX191411
- Product description6-[3-(1-Adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid 95.00%
- Packaging25G
- Price$250
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberAPI-1690
- Product descriptionAdapalene 98%
- Packaging1g
- Price$610
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1690
- Product descriptionAdapalene 97%
- Packaging1g
- Price$610
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging10g
- Price$667
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene >98%(HPLC)
- Packaging25g
- Price$679
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene >98%(HPLC)
- Packaging5g
- Price$200
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ50424
- Product descriptionAdapalene
- Packaging1g
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging1g
- Price$167
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ50424
- Product descriptionAdapalene
- Packaging250mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging100mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene >98%(HPLC)
- Packaging1g
- Price$49
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging250mg
- Price$61
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00388Z | 6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid 99% | 250mg | $8 | 2026-05-28 | Buy |
| aablocks | AA00388Z | 6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid 99% | 1g | $24 | 2026-05-28 | Buy |
| aablocks | AA00388Z | 6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid 99% | 5g | $95 | 2026-05-28 | Buy |
| aablocks | AA00388Z | 6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid 99% | 25g | $344 | 2026-05-28 | Buy |
| ACHEMBLOCK | X191411 | 6-[3-(1-Adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid 95.00% | 25G | $250 | 2026-05-27 | Buy |
| AHH | API-1690 | Adapalene 98% | 1g | $610 | 2021-12-16 | Buy |
| AHH | API-1690 | Adapalene 97% | 1g | $610 | 2026-05-26 | Buy |
| AK Scientific | I810 | Adapalene | 10g | $667 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene >98%(HPLC) | 25g | $679 | 2026-06-04 | Buy |
| AK Scientific | I810 | Adapalene >98%(HPLC) | 5g | $200 | 2026-06-04 | Buy |
| AK Scientific | J50424 | Adapalene | 1g | $125 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 1g | $167 | 2021-12-16 | Buy |
| AK Scientific | J50424 | Adapalene | 250mg | $45 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 100mg | $39 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene >98%(HPLC) | 1g | $49 | 2026-06-04 | Buy |
| AK Scientific | I810 | Adapalene | 250mg | $61 | 2021-12-16 | Buy |
Properties
Melting point :319-3220C
Boiling point :606.3±55.0 °C(Predicted)
Density :1.233±0.06 g/cm3(Predicted)
RTECS :QJ1987000
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :4.2(at 25℃)
form :White solid
color :white to off-white
Merck :14,150
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months
Major Application :pharmaceutical (small molecule)
InChIKey :LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES :C1=C2C(C=C(C3=CC=C(OC)C(C45CC6CC(CC(C6)C4)C5)=C3)C=C2)=CC=C1C(O)=O
CAS DataBase Reference :106685-40-9(CAS DataBase Reference)
Boiling point :606.3±55.0 °C(Predicted)
Density :1.233±0.06 g/cm3(Predicted)
RTECS :QJ1987000
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :4.2(at 25℃)
form :White solid
color :white to off-white
Merck :14,150
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months
Major Application :pharmaceutical (small molecule)
InChIKey :LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES :C1=C2C(C=C(C3=CC=C(OC)C(C45CC6CC(CC(C6)C4)C5)=C3)C=C2)=CC=C1C(O)=O
CAS DataBase Reference :106685-40-9(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||
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Description
Adapalene, a synthetic naphthoic acid derivative, is a selective agonist of retinoic acid receptor (RAR)-β and RAR-γ (Kds = 34 and 130 nM, respectively). At 0.1-10 μM, adapalene dose-dependently inhibits sebocyte growth, proliferation, and differentiation in a primary rat preputial cell culture system. Adapalene demonstrates anti-inflammatory and immunomodulatory activity by inhibiting 5-lipoxygenase-catalyzed leukotriene production and expression of toll-like receptor 2 on human monocytes. It is commonly used for the study of the pathogenesis and treatment of acne vulgaris.Related product price
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Suppliers and manufacturers
Shaanxi Dideu Medichem Co. Ltd
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Wuhan Fortuna Chemical Co., Ltd
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Guangzhou Tosun Pharmaceutical Ltd
Changsha Junyu Chemexpress.co., Ltd
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
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