BMS-754807
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- $42 - $3440
- Product name: BMS-754807
- CAS: 1001350-96-4
- MF: C23H24FN9O
- MW: 461.49
- EINECS:-0
- MDL Number:MFCD18633202
- Synonyms:(2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)aMino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoropyridin-3-yl)-2-Methylpyrrolidine-2-carboxaMide;(S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)aMino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-Methylpyrrolidine-2-carboxaMide;BMS-754807;(2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-2-pyrrolidinecarboxamide;(S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide;(2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-2-pyrrolidinecarboxamide BMS 754807;BMS 754807 (2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-2-pyrrolidinecarboxamide;(S)-1-(1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-2-methylpyrrolidin-2-yl)-2-((6-fluoropyridin-3-yl)amino)ethanone
65 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 10mM(in 1mL DMSO)
- 1mg
- 10mM(in1mLDMSO)
- 10mM*1mLinDMSO(Solid+Solvent)
- 2mg
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1G
- Manufactureraablocks
- Product numberAA008TBT
- Product descriptionBMS-754807 ≥98%
- Packaging5mg
- Price$62
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TBT
- Product descriptionBMS-754807 ≥98%
- Packaging10mg
- Price$112
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TBT
- Product descriptionBMS-754807 98+%
- Packaging25mg
- Price$213
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TBT
- Product descriptionBMS-754807 ≥98%
- Packaging50mg
- Price$416
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TBT
- Product descriptionBMS-754807
- Packaging100mg
- Price$671
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TBT
- Product descriptionBMS-754807 98+%
- Packaging1mg
- Price$42
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65525
- Product description(S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide 98%
- Packaging1G
- Price$1500
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65525
- Product description(S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide 98%
- Packaging1G
- Price$1500
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65525
- Product description(S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide 98%
- Packaging100MG
- Price$300
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65525
- Product description(S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide 98%
- Packaging100MG
- Price$300
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2280AH
- Product descriptionBMS-754807
- Packaging2mg
- Price$199
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001419
- Product descriptionBMS-754807 95.00%
- Packaging5MG
- Price$503.06
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1185
- Product descriptionBMS-754807
- Packaging10mM(in1mLDMSO)
- Price$149
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1185
- Product descriptionBMS-754807
- Packaging25mg
- Price$324
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA1185
- Product descriptionBMS-754807
- Packaging25mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1185
- Product descriptionBMS-754807
- Packaging5mg
- Price$84
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008TBT | BMS-754807 ≥98% | 5mg | $62 | 2026-05-28 | Buy |
| aablocks | AA008TBT | BMS-754807 ≥98% | 10mg | $112 | 2026-05-28 | Buy |
| aablocks | AA008TBT | BMS-754807 98+% | 25mg | $213 | 2026-05-28 | Buy |
| aablocks | AA008TBT | BMS-754807 ≥98% | 50mg | $416 | 2026-05-28 | Buy |
| aablocks | AA008TBT | BMS-754807 | 100mg | $671 | 2026-05-28 | Buy |
| aablocks | AA008TBT | BMS-754807 98+% | 1mg | $42 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q65525 | (S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide 98% | 1G | $1500 | 2026-05-25 | Buy |
| ACHEMBLOCK | Q65525 | (S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide 98% | 1G | $1500 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65525 | (S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide 98% | 100MG | $300 | 2026-05-25 | Buy |
| ACHEMBLOCK | Q65525 | (S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide 98% | 100MG | $300 | 2026-05-27 | Buy |
| AK Scientific | 2280AH | BMS-754807 | 2mg | $199 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001419 | BMS-754807 95.00% | 5MG | $503.06 | 2021-12-16 | Buy |
| ApexBio Technology | A1185 | BMS-754807 | 10mM(in1mLDMSO) | $149 | 2026-05-06 | Buy |
| ApexBio Technology | A1185 | BMS-754807 | 25mg | $324 | 2026-05-06 | Buy |
| ApexBio Technology | A1185 | BMS-754807 | 25mg | $250 | 2021-12-16 | Buy |
| ApexBio Technology | A1185 | BMS-754807 | 5mg | $84 | 2026-05-06 | Buy |
Properties
Density :1.58
storage temp. :room temp
solubility :≥23.05 mg/mL in DMSO; insoluble in H2O; ≥27.75 mg/mL in EtOH
form :powder
color :white to beige
optical activity :[α]/D -86 to -96°, c = 1 in methanol
InChIKey :LQVXSNNAFNGRAH-QHCPKHFHSA-N
SMILES :C[C@@]1(C(NC2=CC=C(F)N=C2)=O)CCCN1C(N=C3NC4=NNC(C5CC5)=C4)=NN6C3=CC=C6
storage temp. :room temp
solubility :≥23.05 mg/mL in DMSO; insoluble in H2O; ≥27.75 mg/mL in EtOH
form :powder
color :white to beige
optical activity :[α]/D -86 to -96°, c = 1 in methanol
InChIKey :LQVXSNNAFNGRAH-QHCPKHFHSA-N
SMILES :C[C@@]1(C(NC2=CC=C(F)N=C2)=O)CCCN1C(N=C3NC4=NNC(C5CC5)=C4)=NN6C3=CC=C6
Safety Information
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Description
BMS 754807 is a reversible, orally bioavailable dual inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine kinases (IC50s = 1.8 and 1.7 nM, respectively). It has minimal effect against an array of other tyrosine and serine/threonine kinases. BMS 754807 inhibits cell proliferation or induces apoptosis in a variety of cancer cells in vitro. It inhibits the growth of tumor xenografts in mice and this effect is often enhanced by combination therapy with other chemotherapeutics. Predictive biomarkers, including elevated IGF-1R expression, for effectiveness of BMS 754807 have been delineated.Related product price
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