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ChemicalBook >> CAS DataBase List >> GSK269962A

GSK269962A

$37 - $4170
Product name: GSK269962A
CAS: 850664-21-0
MF: C29H30N8O5
MW: 570.6
EINECS:
MDL Number:MFCD09970310
Synonyms:GSK 269962;N-[3-[[2-(4-Aminofurazan-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-[[2-(4-morpholinyl)ethyl]oxy]benzamide;GSK269962A(GSK269962);GSK269962A ISO 9001：2015 REACH;GSK269962 (GSK269962A);ROCK inhibitor GSK269962A;GSK-269962 95%;GSK269962B

Price77 Properties Safety Information Description

77 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Tocris
TRC

Package

10mM*1mLinDMSO(Solution)
10mM*1mLinDMSO(Solid+Solvent)
2MG
10mM*1mLinDMSO
1mg
50
10
5mg
10mg
25mg
50mg
100mg
200mg
250mg
500mg
1000mg
1G

Manufactureraablocks
Product numberAA00G3LP
Product descriptionGSK269962A 99%
Packaging1mg
Price$38
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G3LP
Product descriptionGSK269962A 99%
Packaging10mg
Price$79
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G3LP
Product descriptionGSK269962A 99%
Packaging25mg
Price$128
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G3LP
Product descriptionGSK269962A 99%
Packaging50mg
Price$218
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00G3LP
Product descriptionGSK269962A 99%
Packaging100mg
Price$370
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberU135201
Product descriptionGSK269962A 98%
Packaging100MG
Price$695
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberU135201
Product descriptionGSK269962A 98%
Packaging25MG
Price$285
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberU135201
Product descriptionGSK269962A 98%
Packaging1G
Price$4170
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number3703AH
Product descriptionGSK269962A
Packaging5mg
Price$158
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number3703AH
Product descriptionGSK269962A
Packaging1mg
Price$111
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number3703AH
Product descriptionGSK269962A
Packaging10mg
Price$192
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number3703AH
Product descriptionGSK269962A
Packaging250mg
Price$1887
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000296
Product descriptionGSK-269962A 95.00%
Packaging5MG
Price$833.78
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberKIN0000296
Product descriptionGSK-269962A 95.00%
Packaging2MG
Price$516
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB3392
Product descriptionGSK269962A
Packaging50mg
Price$365
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB3392
Product descriptionGSK269962A
Packaging50mg
Price$879
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00G3LP	GSK269962A 99%	1mg	$38	2026-05-28	Buy
aablocks	AA00G3LP	GSK269962A 99%	10mg	$79	2026-05-28	Buy
aablocks	AA00G3LP	GSK269962A 99%	25mg	$128	2026-05-28	Buy
aablocks	AA00G3LP	GSK269962A 99%	50mg	$218	2026-05-28	Buy
aablocks	AA00G3LP	GSK269962A 99%	100mg	$370	2026-05-28	Buy
ACHEMBLOCK	U135201	GSK269962A 98%	100MG	$695	2026-05-27	Buy
ACHEMBLOCK	U135201	GSK269962A 98%	25MG	$285	2026-05-27	Buy
ACHEMBLOCK	U135201	GSK269962A 98%	1G	$4170	2026-05-27	Buy
AK Scientific	3703AH	GSK269962A	5mg	$158	2021-12-16	Buy
AK Scientific	3703AH	GSK269962A	1mg	$111	2021-12-16	Buy
AK Scientific	3703AH	GSK269962A	10mg	$192	2021-12-16	Buy
AK Scientific	3703AH	GSK269962A	250mg	$1887	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000296	GSK-269962A 95.00%	5MG	$833.78	2021-12-16	Buy
American Custom Chemicals Corporation	KIN0000296	GSK-269962A 95.00%	2MG	$516	2021-12-16	Buy
ApexBio Technology	B3392	GSK269962A	50mg	$365	2026-05-06	Buy
ApexBio Technology	B3392	GSK269962A	50mg	$879	2021-12-16	Buy

Next Last

Properties

Melting point :125 - 127°C
Density :1.45
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.19±0.70(Predicted)
color :Off-White

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Two Rho-associated kinases (ROCKS), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. GSK269962 is a selective ROCK inhibitor with IC50 values of 1.6 and 6 nM for ROCK-I and ROCK-II, respectively. It displays greater than 30-fold selectivity for ROCK against a panel of serine/threonine kinases. GSK269962 has been shown to block the generation of inflammatory cytokines in lipopolysaccharide-stimulated monocytes and to induce vasorelaxation in preconstricted rat aorta (IC50 = 35 nM). Oral administration of 1-30 mg/kg GSK269962 can dose-dependently lower blood pressure in spontaneously hypertensive rats.

Suppliers and manufacturers

career henan chemical co

$1.00
N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c] pyridin-6-yl]oxy}phenyl)-4-[2-(4-morpholinyl)ethoxy]benzamide CAS:850664-21-0

TargetMol Chemicals Inc.

$36.00
GSK269962A CAS:850664-21-0

Shaanxi Dideu Medichem Co. Ltd

$1.10
GSK269962A CAS:850664-21-0

ATK CHEMICAL COMPANY LIMITED

CONIER CHEM AND PHARMA LIMITED

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

Hebei Fengjia New Material Co., Ltd

TargetMol Chemicals Inc.

Wuhan Topule Biopharmaceutical Co., Ltd

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GSK269962A

Properties

Safety Information

Description

Suppliers and manufacturers