GW788388
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- $17 - $3024
- Product name: GW788388
- CAS: 452342-67-5
- MF: C25H23N5O2
- MW: 425.48
- EINECS:
- MDL Number:MFCD16038936
- Synonyms:4-[4-[3-(Pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl]-N-(tetrahydropyran-4-yl)benzamide;N-(oxan-4-yl)-4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}benzaMide;GW 788388 4-[4-[3-(Pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl]-N-(tetrahydropyran-4-yl)benzamide;GW 788388;BenzaMide, 4-[4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-2-pyridinyl]-N-(tetrahydro-2H-pyran-4-yl)-;4-(4-(3-(Pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide;GW788388;GW 788388;GW 788388, >=98%
69 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Tocris
- TRC
Package
- 50
- 1mg
- 10mM*1mLinDMSO
- 25mg
- 2mg
- 5mg
- 10mg
- 10
- 50mg
- 10mM(in 1mL DMSO)
- 100MG
- 250.00mg
- 250mg
- 1000mg
- 1G
- 10mM(in1mLDMSO)
- 1.00g
- Manufactureraablocks
- Product numberAA003740
- Product description4-(4-(3-(Pyridin-2-Yl)-1H-Pyrazol-4-Yl)Pyridin-2-Yl)-N-(Tetrahydro-2H-Pyran-4-Yl)Benzamide 98%
- Packaging25mg
- Price$48
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003740
- Product description4-(4-(3-(Pyridin-2-Yl)-1H-Pyrazol-4-Yl)Pyridin-2-Yl)-N-(Tetrahydro-2H-Pyran-4-Yl)Benzamide 98%
- Packaging10mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003740
- Product description4-(4-(3-(Pyridin-2-Yl)-1H-Pyrazol-4-Yl)Pyridin-2-Yl)-N-(Tetrahydro-2H-Pyran-4-Yl)Benzamide 98%
- Packaging5mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003740
- Product description4-(4-(3-(Pyridin-2-Yl)-1H-Pyrazol-4-Yl)Pyridin-2-Yl)-N-(Tetrahydro-2H-Pyran-4-Yl)Benzamide ≥98%
- Packaging250mg
- Price$405
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8882
- Product descriptionGW788388 97%
- Packaging1G
- Price$1050
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8882
- Product descriptionGW788388 97%
- Packaging100MG
- Price$200
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8882
- Product descriptionGW788388 97%
- Packaging5MG
- Price$35
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberH-8882
- Product descriptionGW788388 97%
- Packaging25MG
- Price$70
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX7615
- Product description4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide
- Packaging250mg
- Price$1887
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001485
- Product descriptionGW-788388 95.00%
- Packaging10MG
- Price$267.75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8301
- Product descriptionGW788388
- Packaging25mg
- Price$180
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8301
- Product descriptionGW788388
- Packaging10mM(in 1mL DMSO)
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8301
- Product descriptionGW788388
- Packaging10mM(in1mLDMSO)
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8301
- Product descriptionGW788388
- Packaging5mg
- Price$60
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8301
- Product descriptionGW788388
- Packaging100mg
- Price$385
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberSLK-S2750
- Product descriptionGW788388 99.99%
- Packaging25mg
- Price$352
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003740 | 4-(4-(3-(Pyridin-2-Yl)-1H-Pyrazol-4-Yl)Pyridin-2-Yl)-N-(Tetrahydro-2H-Pyran-4-Yl)Benzamide 98% | 25mg | $48 | 2026-05-28 | Buy |
| aablocks | AA003740 | 4-(4-(3-(Pyridin-2-Yl)-1H-Pyrazol-4-Yl)Pyridin-2-Yl)-N-(Tetrahydro-2H-Pyran-4-Yl)Benzamide 98% | 10mg | $28 | 2026-05-28 | Buy |
| aablocks | AA003740 | 4-(4-(3-(Pyridin-2-Yl)-1H-Pyrazol-4-Yl)Pyridin-2-Yl)-N-(Tetrahydro-2H-Pyran-4-Yl)Benzamide 98% | 5mg | $17 | 2026-05-28 | Buy |
| aablocks | AA003740 | 4-(4-(3-(Pyridin-2-Yl)-1H-Pyrazol-4-Yl)Pyridin-2-Yl)-N-(Tetrahydro-2H-Pyran-4-Yl)Benzamide ≥98% | 250mg | $405 | 2026-05-28 | Buy |
| ACHEMBLOCK | H-8882 | GW788388 97% | 1G | $1050 | 2026-05-27 | Buy |
| ACHEMBLOCK | H-8882 | GW788388 97% | 100MG | $200 | 2026-05-27 | Buy |
| ACHEMBLOCK | H-8882 | GW788388 97% | 5MG | $35 | 2026-05-27 | Buy |
| ACHEMBLOCK | H-8882 | GW788388 97% | 25MG | $70 | 2026-05-27 | Buy |
| AK Scientific | X7615 | 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide | 250mg | $1887 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001485 | GW-788388 95.00% | 10MG | $267.75 | 2021-12-16 | Buy |
| ApexBio Technology | A8301 | GW788388 | 25mg | $180 | 2026-05-06 | Buy |
| ApexBio Technology | A8301 | GW788388 | 10mM(in 1mL DMSO) | $70 | 2021-12-16 | Buy |
| ApexBio Technology | A8301 | GW788388 | 10mM(in1mLDMSO) | $70 | 2026-05-06 | Buy |
| ApexBio Technology | A8301 | GW788388 | 5mg | $60 | 2026-05-06 | Buy |
| ApexBio Technology | A8301 | GW788388 | 100mg | $385 | 2026-05-06 | Buy |
| Arctom | SLK-S2750 | GW788388 99.99% | 25mg | $352 | 2026-05-26 | Buy |
Properties
Density :1.34
storage temp. :2-8°C
solubility :Soluble in DMSO (18 mg/ml with warming)
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
storage temp. :2-8°C
solubility :Soluble in DMSO (18 mg/ml with warming)
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
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Description
GW 788388 is a selective inhibitor of transforming growth factor-β (TGF-β) type 1 receptor (TGFBR1 or ALK5; IC50 = 18 nM). It inhibits the expression of collagen type I in cells (IC50 = 93 nM) and in mice when given orally at 10 mg/kg once a day. As TGF-β stimulates fibrosis in a range of tissues, GW 788388 reduces typical features of fibrosis, including tissue remodeling, increased expression of α-smooth muscle actin and production of collagen I. GW 788388 also blocks TGF-β-mediated production of VEGF by fibroblasts, as well as subsequent angiogenesis in vitro. Inhibition of ALK5 signaling by GW 788388 also induces hypertrophy in femoral growth plates in rats.More related product prices
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