AZ20
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- $25 - $2476
- Product name: AZ20
- CAS: 1233339-22-4
- MF: C21H24N4O3S
- MW: 412.51
- EINECS:
- MDL Number:MFCD25976730
- Synonyms:AZ20;1H-Indole, 4-[4-[(3R)-3-methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-;4-[4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-1H-indole AZ20;AZ20 4-[4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-1H-indole;4-[4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-1H-indole;AZ-20; AZ 20;;CS-1335;(3R)-4-[2-(3H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl]-3-methylmorpholine
77 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Synthonix
- Tocris
- TRC
Package
- 2x5mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 250mg
- 10
- 50
- 10mM*1mLinDMSO
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1G
- Manufactureraablocks
- Product numberAA000KAJ
- Product description(R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine ≥98%
- Packaging1mg
- Price$29
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000KAJ
- Product description(R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98%
- Packaging5mg
- Price$38
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000KAJ
- Product description(R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98%
- Packaging10mg
- Price$57
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000KAJ
- Product description(R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98%
- Packaging25mg
- Price$87
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000KAJ
- Product description(R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98%
- Packaging50mg
- Price$148
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000KAJ
- Product description(R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98%
- Packaging100mg
- Price$251
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10278
- Product descriptionAZ20 98%
- Packaging100MG
- Price$360
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10278
- Product descriptionAZ20 98%
- Packaging100MG
- Price$360
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10278
- Product descriptionAZ20 98%
- Packaging1G
- Price$1350
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10278
- Product descriptionAZ20 98%
- Packaging1G
- Price$1350
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10278
- Product descriptionAZ20 98%
- Packaging25MG
- Price$130
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10278
- Product descriptionAZ20 98%
- Packaging25MG
- Price$130
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10278
- Product descriptionAZ20 98%
- Packaging5MG
- Price$45
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10278
- Product descriptionAZ20 98%
- Packaging5MG
- Price$45
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY1867
- Product descriptionAZ20
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5157
- Product descriptionAZ20
- Packaging50mg
- Price$480
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000KAJ | (R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine ≥98% | 1mg | $29 | 2026-05-25 | Buy |
| aablocks | AA000KAJ | (R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98% | 5mg | $38 | 2026-05-25 | Buy |
| aablocks | AA000KAJ | (R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98% | 10mg | $57 | 2026-05-25 | Buy |
| aablocks | AA000KAJ | (R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98% | 25mg | $87 | 2026-05-25 | Buy |
| aablocks | AA000KAJ | (R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98% | 50mg | $148 | 2026-05-25 | Buy |
| aablocks | AA000KAJ | (R)-4-(2-(1H-Indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine 98% | 100mg | $251 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10278 | AZ20 98% | 100MG | $360 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10278 | AZ20 98% | 100MG | $360 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10278 | AZ20 98% | 1G | $1350 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10278 | AZ20 98% | 1G | $1350 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10278 | AZ20 98% | 25MG | $130 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10278 | AZ20 98% | 25MG | $130 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10278 | AZ20 98% | 5MG | $45 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10278 | AZ20 98% | 5MG | $45 | 2026-05-27 | Buy |
| AK Scientific | Y1867 | AZ20 | 5mg | $130 | 2021-12-16 | Buy |
| AK Scientific | SYN5157 | AZ20 | 50mg | $480 | 2021-12-16 | Buy |
Properties
Melting point :204 °C
Boiling point :634.6±55.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :-20°
solubility :Soluble in DMSO (up to 20 mg/ml).
pka :15.65±0.30(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey :SCGCBAAYLFTIJU-CQSZACIVSA-N
SMILES :N1C2=C(C(C3=NC(C4(S(C)(=O)=O)CC4)=CC(N4CCOC[C@H]4C)=N3)=CC=C2)C=C1
Boiling point :634.6±55.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :-20°
solubility :Soluble in DMSO (up to 20 mg/ml).
pka :15.65±0.30(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey :SCGCBAAYLFTIJU-CQSZACIVSA-N
SMILES :N1C2=C(C(C3=NC(C4(S(C)(=O)=O)CC4)=CC(N4CCOC[C@H]4C)=N3)=CC=C2)C=C1
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
Ataxia telangiectasia and Rad3-related protein (ATR) is a serine/threonine kinase that activates DNA processes related to the DNA damage response. AZ 20 is a potent inhibitor of ATR (IC50 = 5 nM). It displays 7.6-fold selectivity over mTOR and minimal activity against a panel of 442 other kinases, including ataxia telangiectasia mutated. AZ 20 inhibits the growth of LoVo colorectal adenocarcinoma cells in vitro. It is orally bioavailable and significantly reduces the growth of LoVo xenografts in mice.More related product prices
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