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ChemicalBook >> CAS DataBase List >> ICA 069673

ICA 069673

ICA 069673 price.
  • $19 - $1529.85
  • Product name: ICA 069673
  • CAS: 582323-16-8
  • MF: C11H6ClF2N3O
  • MW: 269.63
  • EINECS:
  • MDL Number:MFCD20926351
  • Synonyms:ICA 069673;N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide;ICA069673;ICA-069673;Benzamide, N-(2-chloro-5-pyrimidinyl)-3,4-difluoro-;ICA-069673 >=98% (HPLC);Potassium Channel,ICA 069673,ICA-069673,KcsA,inhibit,Inhibitor;N-(2-Chloropyrimidin-5-yl)-3,4-difluorobenzamide;ICA-069673, 10 mM in DMSO
66 prices
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  • aablocks
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  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
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  • Chemenu
  • ChemScene
  • Crysdot
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  • 1G
  • Manufactureraablocks
  • Product numberAA00EJSP
  • Product descriptionICA 069673 98%
  • Packaging1mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00EJSP
  • Product descriptionICA 069673 98%
  • Packaging5mg
  • Price$49
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00EJSP
  • Product descriptionICA 069673 98%
  • Packaging10mg
  • Price$83
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00EJSP
  • Product descriptionICA 069673 98%
  • Packaging25mg
  • Price$181
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00EJSP
  • Product descriptionICA 069673 98%
  • Packaging50mg
  • Price$318
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00EJSP
  • Product descriptionICA 069673 98%
  • Packaging100mg
  • Price$572
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberZ238599
  • Product descriptionICA-069673 98%
  • Packaging25MG
  • Price$125
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238599
  • Product descriptionICA-069673 98%
  • Packaging100MG
  • Price$330
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number5824CR
  • Product descriptionN-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide
  • Packaging25mg
  • Price$502
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010327
  • Product descriptionN-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00%
  • Packaging10MG
  • Price$669.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010327
  • Product descriptionN-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00%
  • Packaging50MG
  • Price$1004.85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010327
  • Product descriptionN-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00%
  • Packaging1G
  • Price$1529.85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7640
  • Product descriptionICA069673
  • Packaging100mg
  • Price$1433
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7640
  • Product descriptionICA 069673
  • Packaging100mg
  • Price$1170
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7640
  • Product descriptionICA 069673
  • Packaging50mg
  • Price$655
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7640
  • Product descriptionICA 069673
  • Packaging25mg
  • Price$366
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00EJSP ICA 069673 98% 1mg $19 2026-05-28 Buy
aablocks AA00EJSP ICA 069673 98% 5mg $49 2026-05-28 Buy
aablocks AA00EJSP ICA 069673 98% 10mg $83 2026-05-28 Buy
aablocks AA00EJSP ICA 069673 98% 25mg $181 2026-05-28 Buy
aablocks AA00EJSP ICA 069673 98% 50mg $318 2026-05-28 Buy
aablocks AA00EJSP ICA 069673 98% 100mg $572 2026-05-28 Buy
ACHEMBLOCK Z238599 ICA-069673 98% 25MG $125 2026-05-27 Buy
ACHEMBLOCK Z238599 ICA-069673 98% 100MG $330 2026-05-27 Buy
AK Scientific 5824CR N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide 25mg $502 2021-12-16 Buy
American Custom Chemicals Corporation API0010327 N-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00% 10MG $669.9 2021-12-16 Buy
American Custom Chemicals Corporation API0010327 N-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00% 50MG $1004.85 2021-12-16 Buy
American Custom Chemicals Corporation API0010327 N-(2-CHLORO-5-PYRIMIDINYL)-3,4-DIFLUOROBENZAMIDE 95.00% 1G $1529.85 2021-12-16 Buy
ApexBio Technology B7640 ICA069673 100mg $1433 2021-12-16 Buy
ApexBio Technology B7640 ICA 069673 100mg $1170 2026-05-06 Buy
ApexBio Technology B7640 ICA 069673 50mg $655 2026-05-06 Buy
ApexBio Technology B7640 ICA 069673 25mg $366 2026-05-06 Buy

Properties

Boiling point :358.9±37.0 °C(Predicted)
Density :1.539±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DNF:30.0(Max Conc. mg/mL);111.26(Max Conc. mM)
DMSO:36.24(Max Conc. mg/mL);134.4(Max Conc. mM)
Ethanol:30.25(Max Conc. mg/mL);112.18(Max Conc. mM) form :Powder
pka :9.47±0.70(Predicted)
color :White to off-white
InChI :1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)
InChIKey :IIBSHMFXVWTQSJ-UHFFFAOYSA-N
SMILES :O=C(C1=CC=C(F)C(F)=C1)NC2=CN=C(Cl)N=C2

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ICA 069673 is a heteromeric Kv7 channel activator. It is selective for Kv7.2/7.3 over Kv7.3/7.5 (EC50s = 0.69 and 14.3 μM, respectively) and also activates Kv7.4, Kv7.5, and heteromeric Kv7.4/7.5 channels in a dose-dependent manner. ICA 069673 has no activity against hERG, Nav1.5, and Kv7.1 cardiac ion channels (IC50s = >30 μM). Oral administration of ICA 069673 increases latency to first tonic-clonic seizure in the rat maximal electroshock and pentylentetrazol-induced seizure models (ED50s = 1.5 and <1 mg/kg, respectively). Formulations containing ICA 069673 are under clinical investigation for the treatment of epilepsy.

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