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ChemicalBook >> CAS DataBase List >> Infigratinib

Infigratinib

$12 - $5344
Product name: Infigratinib
CAS: 872511-34-7
MF: C26H31Cl2N7O3
MW: 560.48
EINECS:
MDL Number:MFCD22123241
Synonyms:3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea;BGJ 398;BGJ398 (NVP-BGJ398);NVP-BGJ398 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea;Urea, N'-(2,6-dichloro-3,5-dimethoxyphenyl)-N-[6-[[4-(4-ethyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-N-methyl-, methanesulfonate;Urea, N'-(2,6-dichloro-3,5-dimethoxyphenyl)-N-[6-[[4-(4-ethyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-N-methyl-;NVP-BGJ398, >=98%;NVP-BGJ398 (Infigratinib)

Price90 Properties Safety Information Description

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Brand

aablocks
ACHEMBLOCK
Adipogen Life Sciences
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Axon Medchem
Biorbyt Ltd
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Labseeker
TRC
Usbiological

Package

10mM*1mLinDMSO(Solution)
1mg
5mg
10mg
10mM*1mLinDMSO(Solid+Solvent)
20mg
25mg
50mg
100mg
10mM*1mLinDMSO
200mg
250mg
500mg
1G
2g
5g
EvaluationSample

Manufactureraablocks
Product numberAA00GU27
Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
Packaging1mg
Price$12
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU27
Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea ≥98%
Packaging5mg
Price$21
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU27
Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
Packaging10mg
Price$36
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU27
Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
Packaging25mg
Price$54
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU27
Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
Packaging50mg
Price$65
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU27
Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%
Packaging100mg
Price$102
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00GU27
Product description3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea
Packaging500mg
Price$408
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product number10291
Product descriptionBGJ398 98%
Packaging100MG
Price$450
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product number10291
Product descriptionBGJ398 98%
Packaging25MG
Price$150
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product number10291
Product descriptionBGJ398 98%
Packaging1G
Price$1550
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product number10291
Product descriptionBGJ398 98%
Packaging5MG
Price$65
Updated2026-05-27
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1152-M001
Product descriptionNVP-BGJ398 ≥95%
Packaging1mg
Price$65
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1152-M005
Product descriptionNVP-BGJ398 ≥95%
Packaging5mg
Price$113
Updated2021-12-16
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ManufacturerAdipogen Life Sciences
Product numberSYN-1152-M005
Product descriptionNVP-BGJ398 ≥95%
Packaging5mg
Price$113
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1152-M010
Product descriptionNVP-BGJ398 ≥95%
Packaging10mg
Price$178
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1152-M050
Product descriptionNVP-BGJ398 ≥95%
Packaging50mg
Price$416
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00GU27	3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%	1mg	$12	2026-05-28	Buy
aablocks	AA00GU27	3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea ≥98%	5mg	$21	2026-05-28	Buy
aablocks	AA00GU27	3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%	10mg	$36	2026-05-28	Buy
aablocks	AA00GU27	3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%	25mg	$54	2026-05-28	Buy
aablocks	AA00GU27	3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%	50mg	$65	2026-05-28	Buy
aablocks	AA00GU27	3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea 99+%	100mg	$102	2026-05-28	Buy
aablocks	AA00GU27	3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea	500mg	$408	2026-05-28	Buy
ACHEMBLOCK	10291	BGJ398 98%	100MG	$450	2026-05-27	Buy
ACHEMBLOCK	10291	BGJ398 98%	25MG	$150	2026-05-27	Buy
ACHEMBLOCK	10291	BGJ398 98%	1G	$1550	2026-05-27	Buy
ACHEMBLOCK	10291	BGJ398 98%	5MG	$65	2026-05-27	Buy
Adipogen Life Sciences	SYN-1152-M001	NVP-BGJ398 ≥95%	1mg	$65	2026-05-06	Buy
Adipogen Life Sciences	SYN-1152-M005	NVP-BGJ398 ≥95%	5mg	$113	2021-12-16	Buy
Adipogen Life Sciences	SYN-1152-M005	NVP-BGJ398 ≥95%	5mg	$113	2026-05-06	Buy
Adipogen Life Sciences	SYN-1152-M010	NVP-BGJ398 ≥95%	10mg	$178	2026-05-06	Buy
Adipogen Life Sciences	SYN-1152-M050	NVP-BGJ398 ≥95%	50mg	$416	2026-05-06	Buy

Next Last

Properties

Melting point :>211°C (dec.)
Boiling point :747.9±60.0 °C(Predicted)
Density :1.354
storage temp. :-20°C
solubility :Soluble in DMSO (up to 5 mg/ml)
form :White solid.
pka :11.02±0.70(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :QADPYRIHXKWUSV-UHFFFAOYSA-N
SMILES :N(C1C=C(NC2=CC=C(N3CCN(CC)CC3)C=C2)N=CN=1)(C)C(NC1=C(Cl)C(OC)=CC(OC)=C1Cl)=O

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P321	Specific treatment (see … on this label).
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

BGJ398 is an orally available inhibitor of human FGFRs (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively). It inhibits FGFR4 and VEGFR2 with IC50 values of 60 and 180 nM, respectively, and displays comparatively little activity towards Abl, Fyn, Kit, Lck, Lyn, and Yes (IC50s = 0.3-2.5 μM). BGJ398 has been shown to suppress proliferation of cancer cells with wild-type FGFR3 overexpression (IC50s = 5, 30, 32, and 15 nM, for RT112, RT4, SW780, and JMSU1 cells, respectively). In an RT112 bladder cancer xenograft mouse model overexpressing wild-type FGFR3, BGJ398 inhibited tumor growth after oral administration of 10-30 mg/kg.

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Suppliers and manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd

Infigratinib CAS:872511-34-7

Shaanxi Dideu Medichem Co. Ltd

$6000.00
Infigratinib CAS:872511-34-7

Shaanxi Dideu Medichem Co. Ltd

Infigratinib CAS:872511-34-7

shandong perfect biotechnology co.ltd

Infigratinib (BGJ398) CAS:872511-34-7

career henan chemical co

$2.00
3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-[6-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1-methylurea CAS:872511-34-7

PharmOrgSyn Laboratories Co., Ltd.

ATK CHEMICAL COMPANY LIMITED

Biochempartner

Alchem Pharmtech,Inc.

CONIER CHEM AND PHARMA LIMITED

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Infigratinib

Properties

Safety Information

Description

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