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ChemicalBook >> CAS DataBase List >> Itraconazole

Itraconazole

$4 - $1512.16
Product name: Itraconazole
CAS: 84625-61-6
MF: C35H38Cl2N8O4
MW: 705.63
EINECS:617-596-9
MDL Number:MFCD00870168
Synonyms:Oriconazole, R51211, Sporanox;4-[4-[4-[4-[[2-(2，4-Dichlomphenyl)-2-(1H-1，2，4-tfiazol-1- yl-methyl)-1,3-dioxolan-4-y1]methoxyl]phenyl]-1-piperazinyl]phenyl]-2，4-dihydro-2-(1-methylpropyl)-3H-1，2，4-triazol-3-one;Oricomzole;Oyiconazole;3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)- 1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-;Canditral;Sporamelt;4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(1-methylpropyl)-2,4-dihydro-1,2,4-triazol-3-one

Price108 Properties Safety Information Description

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aablocks
AccelPharmtech
Adipogen Life Sciences
AK Scientific
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
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Biosynth
Cayman Chemical
Chem-Impex
ChemScene
Crysdot
CSNpharm
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Medical Isotopes, Inc.
Sigma-Aldrich
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Thermo Scientific Chemicals
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1mg
5mg
10mg
y0001100
20mg
50
i7000000
25mg
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100mg
10mM(in1mLDMSO)
200mg
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1g
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0.025kg
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15 mg
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Manufactureraablocks
Product numberAA003R38
Product descriptionrel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%
Packaging100mg
Price$4
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003R38
Product descriptionrel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%
Packaging250mg
Price$5
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003R38
Product descriptionrel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%
Packaging1g
Price$9
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003R38
Product descriptionrel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%
Packaging5g
Price$23
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003R38
Product descriptionrel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%
Packaging10g
Price$41
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003R38
Product descriptionrel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%
Packaging25g
Price$77
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003R38
Product descriptionrel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one ≥98%
Packaging100g
Price$270
Updated2026-05-28
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ManufacturerAccelPharmtech
Product numberAT5206
Product descriptionItraconazole 99%+
Packaging5G
Price$160
Updated2026-05-21
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ManufacturerAdipogen Life Sciences
Product numberCDX-I0072-M100
Product descriptionItraconazole ≥98%(HPLC)
Packaging100mg
Price$113
Updated2026-05-06
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ManufacturerAK Scientific
Product numberJ51853
Product descriptionItraconazole 95%
Packaging25g
Price$105
Updated2026-06-04
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ManufacturerAK Scientific
Product numberJ10270
Product descriptionItraconazole 99%(HPLC),powder
Packaging25mg
Price$67
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberH151
Product descriptionItraconazole 98%(HPLC)
Packaging5g
Price$133
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberJ10270
Product descriptionItraconazole 99%(HPLC),powder
Packaging100mg
Price$149
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberJ51853
Product descriptionItraconazole 95%
Packaging10g
Price$51
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberJ10270
Product descriptionItraconazole 99%(HPLC),powder
Packaging5mg
Price$39
Updated2026-06-04
Buy

ManufacturerAK Scientific
Product numberH151
Product descriptionItraconazole 98%(HPLC)
Packaging1g
Price$56
Updated2026-06-04
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA003R38	rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%	100mg	$4	2026-05-28	Buy
aablocks	AA003R38	rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%	250mg	$5	2026-05-28	Buy
aablocks	AA003R38	rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%	1g	$9	2026-05-28	Buy
aablocks	AA003R38	rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%	5g	$23	2026-05-28	Buy
aablocks	AA003R38	rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%	10g	$41	2026-05-28	Buy
aablocks	AA003R38	rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 98%	25g	$77	2026-05-28	Buy
aablocks	AA003R38	rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one ≥98%	100g	$270	2026-05-28	Buy
AccelPharmtech	AT5206	Itraconazole 99%+	5G	$160	2026-05-21	Buy
Adipogen Life Sciences	CDX-I0072-M100	Itraconazole ≥98%(HPLC)	100mg	$113	2026-05-06	Buy
AK Scientific	J51853	Itraconazole 95%	25g	$105	2026-06-04	Buy
AK Scientific	J10270	Itraconazole 99%(HPLC),powder	25mg	$67	2026-06-04	Buy
AK Scientific	H151	Itraconazole 98%(HPLC)	5g	$133	2026-06-04	Buy
AK Scientific	J10270	Itraconazole 99%(HPLC),powder	100mg	$149	2026-06-04	Buy
AK Scientific	J51853	Itraconazole 95%	10g	$51	2026-06-04	Buy
AK Scientific	J10270	Itraconazole 99%(HPLC),powder	5mg	$39	2026-06-04	Buy
AK Scientific	H151	Itraconazole 98%(HPLC)	1g	$56	2026-06-04	Buy

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Properties

Melting point :166°C
Boiling point :850.0±75.0 °C(Predicted)
alpha :-0.1～+0.1°(D/20℃)(c=10,CH2Cl2)
Density :1.27 g/cm3
Flash point :>110°(230°F)
storage temp. :2-8°C
solubility :chloroform: 50 mg/mL, clear, colorless
pka :3.7(at 25℃)
form :White powder
color :white
Water Solubility :Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol
Merck :14,5245
Stability :Stable. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions :ANTIMICROBIAL
InChIKey :VHVPQPYKVGDNFY-UHFFFAOYSA-N
SMILES :CCC(C)N1N=CN(C1=O)c2ccc(cc2)N3CCN(CC3)c4ccc(OCC5COC(Cn6cncn6)(O5)c7ccc(Cl)cc7Cl)cc4
CAS DataBase Reference :84625-61-6(CAS DataBase Reference)

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The Hedgehog signaling pathway is critical for embryonic growth and patterning as well as stem cell and progenitor cell tissue homeostasis. Inappropriate Hedgehog activity has been linked to tumor formation. Itraconazole is a systemic antifungal agent with a distinct antagonist effect on Hedgehog signaling. With an IC50 value of 0.8 μM in vitro, itraconazole behaves as an inverse agonist downstream of Patched (Ptch), yet upstream of Smoothened (Smo) to disrupt Hedgehog signaling. Treatment with 100 mg/kg itraconazole twice per day has been shown to suppress the growth of medulloblastomas from a Ptch+/-p53-/- mouse allograft model in as few as five days.

More related product prices

1,4-Dioxane Selenium dioxide Dichlorodiphenylsilane 149-74-6 cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl methanesulphonate 155270-99-8 188116-07-6 IXABEPILONE trans-Itraconazole 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate edoxaban Imatinib 4-([4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-CARBAMIC ACID PHENYL ESTER 4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(2,3,4,4,4-pentadeuterio-3-hydroxybutan-2-yl)-1,2,4-triazol-3-one

Suppliers and manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

$100.00
Itraconazole CAS:84625-61-6

Hebei Yanxi Chemical Co., Ltd.

Itraconazole CAS:84625-61-6

Hebei Chuanghai Biotechnology Co., Ltd

Itraconazole CAS:84625-61-6

Shandong Huisheng Import & Export Co., Ltd.

Itraconazole CAS:84625-61-6

Anhui Zhongda Biotechnology Co., Ltd

Itraconazole CAS:84625-61-6

Anhui Zhongda Biotechnology Co., Ltd

$70.00
Itraconazole CAS:84625-61-6

Anhui Ruihan Technology Co., Ltd

$30.00
Itraconazole CAS:84625-61-6

airuikechemical co., ltd.

itraconazole CAS:84625-61-6

Shaanxi TNJONE Pharmaceutical Co., Ltd

Itraconazole CAS:84625-61-6

Hebei Zhuanglai Chemical Trading Co Ltd

$60.00
Itraconazole CAS:84625-61-6

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Itraconazole

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Description

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