JASPLAKINOLIDE
|
- $169 - $9735
- Product name: JASPLAKINOLIDE
- CAS: 102396-24-7
- MF: C36H45BrN4O6
- MW: 709.67
- EINECS:
- MDL Number:MFCD00873735
- Synonyms:JASPLAKINOLIDE;JASPLAKINOLIDE, JASPIS JOHNSTONI;(3S,6R,9R,13S,15R,16E,19S)-3,5,13,15,17,19-Hexamethyl-6-[(2-bromo-1H-indole-3-yl)methyl]-9-(4-hydroxyphenyl)-12-oxa-2,5,8-triazacyclononadeca-16-ene-1,4,7,11-tetraone;[3S,6R,9R,13S,15R,19S,16E,(+)]-6-[(2-Bromo-1H-indol-3-yl)methyl]-9-(4-hydroxyphenyl)-3,5,13,15,17,19-hexamethyl-2,5,8-triaza-12-oxacyclononadecan-16-ene-1,4,7,11-tetrone;NSC 613009;Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem;Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl];GQWYWHOHRVVHAP-DHKPLNAMSA-N
31 prices
Selected condition:
Brand
- Adipogen Life Sciences
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50ug
- 50μg
- 0.1mg
- 100ug
- 100μg
- 0.25mg
- 0.5mg
- 1mg
- 2mg
- 100U
- 1 unit
- 50 μg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0037-C050
- Product descriptionJasplakinolide (high purity) ≥98%(HPLC)
- Packaging50μg
- Price$260
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0037-C100
- Product descriptionJasplakinolide(highpurity) ≥98%(HPLC)
- Packaging100μg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0037-C100
- Product descriptionJasplakinolide (high purity) ≥98%(HPLC)
- Packaging100μg
- Price$430
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7189
- Product descriptionJasplakinolide
- Packaging50ug
- Price$450
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7189
- Product descriptionJasplakinolide
- Packaging100ug
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7189
- Product descriptionJasplakinolide
- Packaging50ug
- Price$229
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-P0027
- Product descriptionJasplakinolide 99.56%
- Packaging50μg
- Price$629
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-P0027
- Product descriptionJasplakinolide 99.56%
- Packaging100μg
- Price$1007
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberCEA39624
- Product descriptionJasplakinolide
- Packaging0.25mg
- Price$1460.25
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCEA39624
- Product descriptionJasplakinolide
- Packaging0.5mg
- Price$2596
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCEA39624
- Product descriptionJasplakinolide
- Packaging1mg
- Price$5127.1
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCEA39624
- Product descriptionJasplakinolide
- Packaging2mg
- Price$9735
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberCEA39624
- Product descriptionJasplakinolide
- Packaging0.1mg
- Price$649
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number11705
- Product descriptionJasplakinolide ≥95%
- Packaging50μg
- Price$237
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number11705
- Product descriptionJasplakinolide ≥98%
- Packaging50μg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11705
- Product descriptionJasplakinolide ≥98%
- Packaging100μg
- Price$287
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0037-C050 | Jasplakinolide (high purity) ≥98%(HPLC) | 50μg | $260 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0037-C100 | Jasplakinolide(highpurity) ≥98%(HPLC) | 100μg | $280 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0037-C100 | Jasplakinolide (high purity) ≥98%(HPLC) | 100μg | $430 | 2026-05-06 | Buy |
| ApexBio Technology | B7189 | Jasplakinolide | 50ug | $450 | 2026-05-06 | Buy |
| ApexBio Technology | B7189 | Jasplakinolide | 100ug | $390 | 2021-12-16 | Buy |
| ApexBio Technology | B7189 | Jasplakinolide | 50ug | $229 | 2021-12-16 | Buy |
| Arctom | HY-P0027 | Jasplakinolide 99.56% | 50μg | $629 | 2026-05-26 | Buy |
| Arctom | HY-P0027 | Jasplakinolide 99.56% | 100μg | $1007 | 2026-05-26 | Buy |
| Biosynth | CEA39624 | Jasplakinolide | 0.25mg | $1460.25 | 2026-06-04 | Buy |
| Biosynth | CEA39624 | Jasplakinolide | 0.5mg | $2596 | 2026-06-04 | Buy |
| Biosynth | CEA39624 | Jasplakinolide | 1mg | $5127.1 | 2026-06-04 | Buy |
| Biosynth | CEA39624 | Jasplakinolide | 2mg | $9735 | 2026-06-04 | Buy |
| Biosynth | CEA39624 | Jasplakinolide | 0.1mg | $649 | 2026-06-04 | Buy |
| Cayman Chemical | 11705 | Jasplakinolide ≥95% | 50μg | $237 | 2026-04-30 | Buy |
| Cayman Chemical | 11705 | Jasplakinolide ≥98% | 50μg | $169 | 2024-03-01 | Buy |
| Cayman Chemical | 11705 | Jasplakinolide ≥98% | 100μg | $287 | 2024-03-01 | Buy |
Properties
Melting point :110℃ (decomposition)
storage temp. :-20°C
solubility :DMSO: >2mg/mL
form :Off-white solid
color :off white to beige
InChIKey :GQWYWHOHRVVHAP-DHKPLNAMSA-N
SMILES :C[C@H]1C[C@@H](C)\C=C(C)\C[C@H](C)C(=O)N[C@@H](C)C(=O)N(C)[C@H](Cc2c(Br)[nH]c3ccccc23)C(=O)N[C@H](CC(=O)O1)c4ccc(O)cc4
storage temp. :-20°C
solubility :DMSO: >2mg/mL
form :Off-white solid
color :off white to beige
InChIKey :GQWYWHOHRVVHAP-DHKPLNAMSA-N
SMILES :C[C@H]1C[C@@H](C)\C=C(C)\C[C@H](C)C(=O)N[C@@H](C)C(=O)N(C)[C@H](Cc2c(Br)[nH]c3ccccc23)C(=O)N[C@H](CC(=O)O1)c4ccc(O)cc4
Safety Information
| Symbol(GHS): | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | |||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Jasplakinolide is a natural macrocyclic peptide first isolated from a marine sponge. It potently inhibits the proliferation of PC3 prostate carcinoma cells (IC50 = 35 nM) by binding F-actin (KD = 15 nM). This binding of jasplakinolide to actin, which is competitive with phalloidin, stabilizes actin filaments in vitro but disrupts actin filaments and induces irregular polymerization of monomeric actin in vivo. This compound is used to investigate the role of actin in diverse cellular roles, such as motility, transport, and development.More related product prices
Ribonucleic acid Carboxymethyl cellulose Anthraquinone NS-398 Acrylic acid Morpholine ParaformaldehydeRelated product price
-
Ribonucleic acid
$45-3950 -
Carboxymethyl cellulose
$8-6565.02 -
Anthraquinone
$5-1348




