JERVINE
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- $15 - $1800
- Product name: JERVINE
- CAS: 469-59-0
- MF: C27H39NO3
- MW: 425.6
- EINECS:207-417-9
- MDL Number:MFCD01684066
- Synonyms:Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetraMethyl-,(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-;17,23-epoxy-3-hydroxy-,(3-beta,23-beta)-veratraman-11-on ;17,23-epoxy-3-hydroxy-,(3beta,23beta)-veratraman-11-on ;4’,5’,6,6’,6a,6b,7,7’,7’a,8,11a,11b-hexadecahydro-3-hydroxy-3’,6’,10,11b-tetra ;Iervin;(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one;jerwiny ;Spiro(9H-benzo(a)fluorene-9,2'(3'H)-furo(3,2-b)-pyridin)-11(1H)-one,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-
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Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 20mg
- 10
- 5mg
- 10mg
- 0.025g
- 25MG
- 0.05g
- 50mg
- 100MG
- 0.1g
- 0.25g
- 250MG
- 0.5g
- 500mg
- 1000mg
- 1g
- Manufactureraablocks
- Product numberAA00D9OS
- Product descriptionJervine ≥97%(HPLC)
- Packaging5mg
- Price$15
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00D9OS
- Product descriptionJervine ≥97%(HPLC)
- Packaging10mg
- Price$29
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberV143149
- Product descriptionJervine 98%
- Packaging25MG
- Price$325
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV143149
- Product descriptionJervine 98%
- Packaging100MG
- Price$900
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV143149
- Product descriptionJervine 98%
- Packaging250MG
- Price$1800
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberX0086
- Product descriptionJervine
- Packaging50mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX0086
- Product descriptionJervine
- Packaging5mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8656
- Product descriptionJervine
- Packaging5mg
- Price$109
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8656
- Product descriptionJervine
- Packaging10mg
- Price$203
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8656
- Product descriptionJervine
- Packaging50mg
- Price$1319
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8656
- Product descriptionJervine
- Packaging50mg
- Price$880
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-N0836R
- Product descriptionJervine (Standard)
- Packaging25mg
- Price$883
- Updated2026-05-25
- Buy
- ManufacturerArctom
- Product numberHY-N0836R
- Product descriptionJervine (Standard)
- Packaging25mg
- Price$883
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N0836
- Product descriptionJervine 99.28%
- Packaging100mg
- Price$867
- Updated2026-05-25
- Buy
- ManufacturerArctom
- Product numberHY-N0836
- Product descriptionJervine 99.28%
- Packaging100mg
- Price$867
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N0836R
- Product descriptionJervine (Standard)
- Packaging50mg
- Price$1236
- Updated2026-05-25
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00D9OS | Jervine ≥97%(HPLC) | 5mg | $15 | 2026-05-28 | Buy |
| aablocks | AA00D9OS | Jervine ≥97%(HPLC) | 10mg | $29 | 2026-05-28 | Buy |
| ACHEMBLOCK | V143149 | Jervine 98% | 25MG | $325 | 2026-05-27 | Buy |
| ACHEMBLOCK | V143149 | Jervine 98% | 100MG | $900 | 2026-05-27 | Buy |
| ACHEMBLOCK | V143149 | Jervine 98% | 250MG | $1800 | 2026-05-27 | Buy |
| AK Scientific | X0086 | Jervine | 50mg | $410 | 2021-12-16 | Buy |
| AK Scientific | X0086 | Jervine | 5mg | $158 | 2021-12-16 | Buy |
| ApexBio Technology | A8656 | Jervine | 5mg | $109 | 2026-05-06 | Buy |
| ApexBio Technology | A8656 | Jervine | 10mg | $203 | 2026-05-06 | Buy |
| ApexBio Technology | A8656 | Jervine | 50mg | $1319 | 2021-12-16 | Buy |
| ApexBio Technology | A8656 | Jervine | 50mg | $880 | 2026-05-06 | Buy |
| Arctom | HY-N0836R | Jervine (Standard) | 25mg | $883 | 2026-05-25 | Buy |
| Arctom | HY-N0836R | Jervine (Standard) | 25mg | $883 | 2026-05-26 | Buy |
| Arctom | HY-N0836 | Jervine 99.28% | 100mg | $867 | 2026-05-25 | Buy |
| Arctom | HY-N0836 | Jervine 99.28% | 100mg | $867 | 2026-05-26 | Buy |
| Arctom | HY-N0836R | Jervine (Standard) | 50mg | $1236 | 2026-05-25 | Buy |
Properties
Melting point :242- 244°C
alpha :D20 -150° (ethanol) (Saito); D20 -167.6° (chloroform) (Poethke)
Boiling point :541.31°C (rough estimate)
Density :1.18±0.1 g/cm3 (20 ºC 760 Torr)
refractive index :1.6400 (estimate)
storage temp. :−20°C
solubility :methanol: >2 mg/mL
form :solid
pka :14.98±0.70(Predicted)
color :White
λmax :250nm(lit.)
Merck :14,5264
Stability :Store in Freezer at - 20°C
InChIKey :CLEXYFLHGFJONT-DNMILWOZSA-N
SMILES :[H][C@@]12C[C@H](C)CN[C@@]1([H])[C@@H](C)[C@@]3(CC[C@]4([H])C(=C3C)C(=O)[C@@]5([H])[C@@]4([H])CC=C6C[C@@H](O)CC[C@]56C)O2
alpha :D20 -150° (ethanol) (Saito); D20 -167.6° (chloroform) (Poethke)
Boiling point :541.31°C (rough estimate)
Density :1.18±0.1 g/cm3 (20 ºC 760 Torr)
refractive index :1.6400 (estimate)
storage temp. :−20°C
solubility :methanol: >2 mg/mL
form :solid
pka :14.98±0.70(Predicted)
color :White
λmax :250nm(lit.)
Merck :14,5264
Stability :Store in Freezer at - 20°C
InChIKey :CLEXYFLHGFJONT-DNMILWOZSA-N
SMILES :[H][C@@]12C[C@H](C)CN[C@@]1([H])[C@@H](C)[C@@]3(CC[C@]4([H])C(=C3C)C(=O)[C@@]5([H])[C@@]4([H])CC=C6C[C@@H](O)CC[C@]56C)O2
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||
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Description
Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog signaling. This is derived from the Veratrum plant species. It is a close structural analog of cyclopamine which specifically inhibits the hedgehog (Hh) pathway by interaction with the hedgehog signaling protein Smo. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Jervine is an inhibitor of Smo.More related product prices
329196-48-7 LDE-225 Diphosphate Smoothened Agonist, HCl PROTOVERATRINE A VERATRIDINE veratramine 35158-25-9 DL-IsoleucineRelated product price
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329196-48-7
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Suppliers and manufacturers
Shanghai Standard Technology Co., Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Neostar United (Changzhou) Industrial Co., Ltd.
Wuhan ChemNorm Biotech Co.,Ltd.
Hubei Ipure Biology Co., Ltd
Jervine
CAS:469-59-0
