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ChemicalBook >> CAS DataBase List >> NSC 23766 (hydrochloride)

NSC 23766 (hydrochloride)

NSC 23766 (hydrochloride) price.
  • $19 - $1900
  • Product name: NSC 23766 (hydrochloride)
  • CAS: 1177865-17-6
  • MF: C24H35N7
  • MW: 421.5816
  • EINECS:
  • MDL Number:MFCD08703096
  • Synonyms:NSC 23766 (hydrochloride);NSC 23766 (trihydrochloride);NSC23766 trihydrochloride;NSC-23766 trihydrochloride;N6-[2-(4-Diethylamino-1-methyl-butylamino)-6-methyl-pyrimidin-4-yl]-2-methyl-quinoline-4,6-diamine trihydrochloride;NSC-23766 HCl;NSC 23766, >=98%;Rac1 Inhibitor
63 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM(in1mLDMSO)
  • 10mM(in 1mL DMSO)
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA008SPE
  • Product descriptionN6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride
  • Packaging5mg
  • Price$63
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008SPE
  • Product descriptionN6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride
  • Packaging10mg
  • Price$88
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008SPE
  • Product descriptionN6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride
  • Packaging25mg
  • Price$145
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008SPE
  • Product descriptionN6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride
  • Packaging100mg
  • Price$359
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008SPE
  • Product descriptionN6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride
  • Packaging50mg
  • Price$252
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008SPE
  • Product descriptionN6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride ≥98%
  • Packaging1mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230562
  • Product descriptionNSC 23766 trihydrochloride 98%
  • Packaging25MG
  • Price$185
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230562
  • Product descriptionNSC 23766 trihydrochloride 98%
  • Packaging100MG
  • Price$505
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number7350BB
  • Product descriptionNSC23766 trihydrochloride
  • Packaging25mg
  • Price$363
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001309
  • Product descriptionN6-[2-[[4-(DIETHYLAMINO)-1-METHYLBUTYL]AMINO]-6-METHYL-4-PYRIMIDINYL]-2-METHYL-4,6-QUINOLINEDIAMINE TRIHYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$497.05
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1952
  • Product descriptionNSC23766 trihydrochloride
  • Packaging100mg
  • Price$528
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1952
  • Product descriptionNSC 23766
  • Packaging100mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1952
  • Product descriptionNSC 23766
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1952
  • Product descriptionNSC23766 trihydrochloride
  • Packaging25mg
  • Price$220
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1952
  • Product descriptionNSC23766 trihydrochloride
  • Packaging5mg
  • Price$55
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1952
  • Product descriptionNSC 23766
  • Packaging10mM(in 1mL DMSO)
  • Price$98
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008SPE N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride 5mg $63 2026-05-28 Buy
aablocks AA008SPE N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride 10mg $88 2026-05-28 Buy
aablocks AA008SPE N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride 25mg $145 2026-05-28 Buy
aablocks AA008SPE N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride 100mg $359 2026-05-28 Buy
aablocks AA008SPE N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride 50mg $252 2026-05-28 Buy
aablocks AA008SPE N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine trihydrochloride ≥98% 1mg $19 2026-05-28 Buy
ACHEMBLOCK Y230562 NSC 23766 trihydrochloride 98% 25MG $185 2026-05-27 Buy
ACHEMBLOCK Y230562 NSC 23766 trihydrochloride 98% 100MG $505 2026-05-27 Buy
AK Scientific 7350BB NSC23766 trihydrochloride 25mg $363 2021-12-16 Buy
American Custom Chemicals Corporation INB0001309 N6-[2-[[4-(DIETHYLAMINO)-1-METHYLBUTYL]AMINO]-6-METHYL-4-PYRIMIDINYL]-2-METHYL-4,6-QUINOLINEDIAMINE TRIHYDROCHLORIDE 95.00% 5MG $497.05 2021-12-16 Buy
ApexBio Technology A1952 NSC23766 trihydrochloride 100mg $528 2026-05-06 Buy
ApexBio Technology A1952 NSC 23766 100mg $480 2021-12-16 Buy
ApexBio Technology A1952 NSC 23766 25mg $200 2021-12-16 Buy
ApexBio Technology A1952 NSC23766 trihydrochloride 25mg $220 2026-05-06 Buy
ApexBio Technology A1952 NSC23766 trihydrochloride 5mg $55 2026-05-06 Buy
ApexBio Technology A1952 NSC 23766 10mM(in 1mL DMSO) $98 2021-12-16 Buy

Properties

Melting point :>225°C (dec.)
storage temp. :-20°C
solubility :H2O: soluble10mg/mL, clear
form :powder
color :white to beige
Water Solubility :water: 5mg/mL
InChIKey :CPUHORIUXPQCHW-UHFFFAOYSA-N
SMILES :Cl.Cl.Cl.N(CCCC(Nc1nc(cc(n1)C)Nc2cc3c(nc(cc3N)C)cc2)C)(CC)CC

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Rac1 is a GTPase that is involved in the regulation of the cell cycle, cell-cell adhesion, motility, and differentiation. Rac1 is activated by its interaction with specific guanine nucleotide exchange factors (GEFs). NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 μM). It has no effect on the closely related GTPases, Cdc42 and RhoA. NSC23766 has been used to investigate the role of Rac1 in such diverse cellular functions as stem cell mobilization, epithelial cell migration, angiogenesis, leukemia cell migration and growth, and gene expression.

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