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ChemicalBook >> CAS DataBase List >> PAXILLINE

PAXILLINE

PAXILLINE price.
  • $45 - $5076
  • Product name: PAXILLINE
  • CAS: 57186-25-1
  • MF: C27H33NO4
  • MW: 435.56
  • EINECS:637-206-0
  • MDL Number:MFCD00083464
  • Synonyms:(2R)-5,6,6aα,7,12,12b,12c,13,14,14aβ-Decahydro-4bβ-hydroxy-2-(1-hydroxy-1-methylethyl)-12bβ,12cα-dimethyl-2H-1-benzopyrano[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one;2h-1-benzopyrano(5’,6’:6,7)indeno(1,2-b)indol-3(4bh)-one,5,6,6a,7,12,12b,12c,1 ;4b-beta,6a-alpha,12b-beta,12c-alpha,14a-beta)-2-alph ;paxilline from penicillium paxilli;PAXILINE;Paxicillin;(2R,4bS,6aS,12bS,12cR,14aS)-4b-Hydroxy-2-(1-hydroxy-1-methylethyl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5′,6′:6,7]indeno[1,2-b]indol-3(4bH)-one solution;Paxilline solution
55 prices
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Brand
  • aablocks
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Thermo Scientific Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 0.01g
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  • 50mg
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  • Manufactureraablocks
  • Product numberAA00E9IW
  • Product description(2R,4bS,6aS,12bS,12cR,14aS)-4b-Hydroxy-2-(2-hydroxypropan-2-yl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one ≥98%
  • Packaging1mg
  • Price$50
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00E9IW
  • Product description(2R,4bS,6aS,12bS,12cR,14aS)-4b-Hydroxy-2-(2-hydroxypropan-2-yl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one ≥98%
  • Packaging5mg
  • Price$134
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00E9IW
  • Product description(2R,4bS,6aS,12bS,12cR,14aS)-4b-Hydroxy-2-(2-hydroxypropan-2-yl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one ≥98%
  • Packaging10mg
  • Price$242
  • Updated2026-05-28
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0167-M001
  • Product descriptionPaxilline ≥95%(HPLC)
  • Packaging1mg
  • Price$45
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0167-M005
  • Product descriptionPaxilline ≥95%(HPLC)
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0167-M005
  • Product descriptionPaxilline ≥95%(HPLC)
  • Packaging5mg
  • Price$120
  • Updated2026-05-06
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  • ManufacturerAHH
  • Product numberMT-57661
  • Product descriptionPaxilline 98%
  • Packaging0.01g
  • Price$230
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-57661
  • Product descriptionPaxilline 97%
  • Packaging0.01g
  • Price$230
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-57661
  • Product descriptionPaxilline 97%
  • Packaging0.01g
  • Price$230
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product number8972AJ
  • Product descriptionPaxilline
  • Packaging5mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6920
  • Product descriptionPaxilline
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6920
  • Product descriptionPaxilline
  • Packaging5mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6920
  • Product descriptionPaxilline
  • Packaging5mg
  • Price$183
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6920
  • Product descriptionPaxilline
  • Packaging10mg
  • Price$333
  • Updated2026-05-06
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIP1004
  • Product descriptionPaxilline from Penicillium paxilli
  • Packaging10mg
  • Price$330
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIP1004
  • Product descriptionPaxilline from Penicillium paxilli
  • Packaging5mg
  • Price$184
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00E9IW (2R,4bS,6aS,12bS,12cR,14aS)-4b-Hydroxy-2-(2-hydroxypropan-2-yl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one ≥98% 1mg $50 2026-05-28 Buy
aablocks AA00E9IW (2R,4bS,6aS,12bS,12cR,14aS)-4b-Hydroxy-2-(2-hydroxypropan-2-yl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one ≥98% 5mg $134 2026-05-28 Buy
aablocks AA00E9IW (2R,4bS,6aS,12bS,12cR,14aS)-4b-Hydroxy-2-(2-hydroxypropan-2-yl)-12b,12c-dimethyl-5,6,6a,7,12,12b,12c,13,14,14a-decahydro-2H-chromeno[5',6':6,7]indeno[1,2-b]indol-3(4bH)-one ≥98% 10mg $242 2026-05-28 Buy
Adipogen Life Sciences AG-CN2-0167-M001 Paxilline ≥95%(HPLC) 1mg $45 2026-05-06 Buy
Adipogen Life Sciences AG-CN2-0167-M005 Paxilline ≥95%(HPLC) 5mg $120 2021-12-16 Buy
Adipogen Life Sciences AG-CN2-0167-M005 Paxilline ≥95%(HPLC) 5mg $120 2026-05-06 Buy
AHH MT-57661 Paxilline 98% 0.01g $230 2021-12-16 Buy
AHH MT-57661 Paxilline 97% 0.01g $230 2026-05-25 Buy
AHH MT-57661 Paxilline 97% 0.01g $230 2026-05-26 Buy
AK Scientific 8972AJ Paxilline 5mg $233 2021-12-16 Buy
ApexBio Technology B6920 Paxilline 10mg $250 2021-12-16 Buy
ApexBio Technology B6920 Paxilline 5mg $138 2021-12-16 Buy
ApexBio Technology B6920 Paxilline 5mg $183 2026-05-06 Buy
ApexBio Technology B6920 Paxilline 10mg $333 2026-05-06 Buy
Apolloscientific BIP1004 Paxilline from Penicillium paxilli 10mg $330 2026-06-04 Buy
Apolloscientific BIP1004 Paxilline from Penicillium paxilli 5mg $184 2026-06-04 Buy

Properties

Flash point :2℃
storage temp. :2-8°C
solubility :Soluble in DMSO, acetone or chloroform.
form :powder
color :faint yellow
Major Application :cleaning products
cosmetics
food and beverages
personal care InChIKey :ACNHBCIZLNNLRS-UBGQALKQSA-N
SMILES :N1C2=C(C=CC=C2)C2C[C@@]3([H])[C@](C)(C1=2)[C@@]1(C)CC[C@]2([H])O[C@H](C(O)(C)C)C(=O)C=C2[C@]1(O)CC3

Safety Information

Symbol(GHS): Corrosion (GHS05)Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Paxilline is an indole diterpene from fungi which potently and reversibly inhibits large conductance Ca2+-activated K+ (BKCa) channels, as shown in patch clamp (Ki = 1.9 nM) and whole smooth muscle cell studies (Ki = 35.7 nM). It also enhances the binding of charybdotoxin, a peptidyl neurotoxin, to BKCa channels. Paxilline is currently used to evaluate the role of BKCa channels in various cell processes and responses.

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