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ChemicalBook >> CAS DataBase List >> PF-4708671

PF-4708671

PF-4708671 price.
  • $15 - $2841
  • Product name: PF-4708671
  • CAS: 1255517-76-0
  • MF: C19H21F3N6
  • MW: 390.41
  • EINECS:
  • MDL Number:MFCD18086922
  • Synonyms:2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole;PF 4708671;PF4708671/PF-4708671;2-[[4-(5-ethyl-4-pyriMidinyl)-1-piperazinyl]Methyl]-6-(trifluoroMethyl)-1H-benziMidazole;PF-04708671;1H-Benzimidazole, 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-;2-[[4-(5-Ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole PF-4708671;2-[[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-6-(trifluoromethyl)-1H-benzimidazole
85 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • 10mM(1mLinDMSO)
  • 0.1g
  • 5
  • 25
  • 1000mg
  • 10mM*1mLinDMSO
  • 10mM(in1mLDMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1G
  • Manufactureraablocks
  • Product numberAA009CBD
  • Product descriptionPF-4708671 98%
  • Packaging25mg
  • Price$79
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CBD
  • Product descriptionPF-4708671 98%
  • Packaging50mg
  • Price$108
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CBD
  • Product descriptionPF-4708671 98%
  • Packaging100mg
  • Price$198
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CBD
  • Product descriptionPF-4708671 98%
  • Packaging5mg
  • Price$31
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CBD
  • Product descriptionPF-4708671 98%
  • Packaging1mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CBD
  • Product descriptionPF-4708671 98%
  • Packaging10mg
  • Price$48
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70185
  • Product descriptionPF 4708671 98%
  • Packaging100MG
  • Price$440
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70185
  • Product descriptionPF 4708671 98%
  • Packaging100MG
  • Price$440
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70185
  • Product descriptionPF 4708671 98%
  • Packaging1G
  • Price$2200
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ70185
  • Product descriptionPF 4708671 98%
  • Packaging1G
  • Price$2200
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2644AH
  • Product description2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-6-(trifluoromethyl)-1H-benzo[d]imidazole
  • Packaging5mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging1mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging5mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging250mg
  • Price$318
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130606
  • Product descriptionPF-4708671 98+%
  • Packaging100mg
  • Price$212
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009CBD PF-4708671 98% 25mg $79 2026-05-28 Buy
aablocks AA009CBD PF-4708671 98% 50mg $108 2026-05-28 Buy
aablocks AA009CBD PF-4708671 98% 100mg $198 2026-05-28 Buy
aablocks AA009CBD PF-4708671 98% 5mg $31 2026-05-28 Buy
aablocks AA009CBD PF-4708671 98% 1mg $16 2026-05-28 Buy
aablocks AA009CBD PF-4708671 98% 10mg $48 2026-05-28 Buy
ACHEMBLOCK Q70185 PF 4708671 98% 100MG $440 2026-05-25 Buy
ACHEMBLOCK Q70185 PF 4708671 98% 100MG $440 2026-05-27 Buy
ACHEMBLOCK Q70185 PF 4708671 98% 1G $2200 2026-05-25 Buy
ACHEMBLOCK Q70185 PF 4708671 98% 1G $2200 2026-05-27 Buy
AK Scientific 2644AH 2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-6-(trifluoromethyl)-1H-benzo[d]imidazole 5mg $116 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 10mg $55 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 1mg $15 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 5mg $37 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 250mg $318 2021-12-16 Buy
Ambeed A130606 PF-4708671 98+% 100mg $212 2021-12-16 Buy

Properties

Boiling point :572.8±50.0 °C(Predicted)
Density :1.348±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥20mg/mL
form :powder
pka :10.20±0.10(Predicted)
color :off-white
InChI :1S/C19H21F3N6/c1-2-13-10-23-12-24-18(13)28-7-5-27(6-8-28)11-17-25-15-4-3-14(19(20,21)22)9-16(15)26-17/h3-4,9-10,12H,2,5-8,11H2,1H3,(H,25,26)
InChIKey :FBLPQCAQRNSVHB-UHFFFAOYSA-N
SMILES :CCC(C=NC=N1)=C1N2CCN(CC3=NC4=C(C=CC(C(F)(F)F)=C4)N3)CC2

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-04708671 is a specific, cell-permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, MSK, or RSK, or many other unrelated kinases, under conditions in which it inhibits S6K1 activity. It is useful in evaluating the role of S6K1 and, indirectly, mTORC1, in cell signaling.

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