PLERIXAFOR
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- $12 - $15400
- Product name: PLERIXAFOR
- CAS: 110078-46-1
- MF: C28H54N8
- MW: 502.78
- EINECS:1592732-453-0
- MDL Number:MFCD05662218
- Synonyms:1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane;1,4,8,11-Tetraazacyclotetradecane, 1,1'-(1,4-phenylenebis(methylene))bis-;Mozobil;Sdz sid 791;Unii-S915p5499n;1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane;Plerixafor(AMD3100);1-{[4-(1,4,8,11-tetraazacyclotetradecan-1-ylMethyl)phenyl]Methyl}-1,4,8,11-tetraazacyclotetradecane
83 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- TCI Chemical
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 20mg
- 10mM(in1mLEthanol)
- 25mg
- 50mg
- 100mg
- 200mg
- 10mM(in 1mL Ethanol)
- 250mg
- 250.00mg
- 500mg
- 1.00g
- 1g
- 5g
- Manufactureraablocks
- Product numberAA007VV1
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 98%
- Packaging5g
- Price$1653
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VV1
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99%
- Packaging1g
- Price$358
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VV1
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 98%
- Packaging250mg
- Price$185
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VV1
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 98%
- Packaging100mg
- Price$113
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VV1
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene ≥98%
- Packaging50mg
- Price$105
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VV1
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene ≥98%
- Packaging10mg
- Price$28
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VV1
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product number10246
- Product descriptionPlerixafor 98%
- Packaging250MG
- Price$105
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10246
- Product descriptionPlerixafor 98%
- Packaging250MG
- Price$105
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10246
- Product descriptionPlerixafor 98%
- Packaging1G
- Price$210
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10246
- Product descriptionPlerixafor 98%
- Packaging1G
- Price$210
- Updated2026-05-27
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging250mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging10mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging50mg
- Price$43
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging5mg
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging100mg
- Price$68
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007VV1 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 98% | 5g | $1653 | 2026-05-28 | Buy |
| aablocks | AA007VV1 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99% | 1g | $358 | 2026-05-28 | Buy |
| aablocks | AA007VV1 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 98% | 250mg | $185 | 2026-05-28 | Buy |
| aablocks | AA007VV1 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 98% | 100mg | $113 | 2026-05-28 | Buy |
| aablocks | AA007VV1 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene ≥98% | 50mg | $105 | 2026-05-28 | Buy |
| aablocks | AA007VV1 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene ≥98% | 10mg | $28 | 2026-05-28 | Buy |
| aablocks | AA007VV1 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99% | 1mg | $12 | 2026-05-28 | Buy |
| ACHEMBLOCK | 10246 | Plerixafor 98% | 250MG | $105 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10246 | Plerixafor 98% | 250MG | $105 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10246 | Plerixafor 98% | 1G | $210 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10246 | Plerixafor 98% | 1G | $210 | 2026-05-27 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 250mg | $164 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 10mg | $25 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 50mg | $43 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 5mg | $19 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 100mg | $68 | 2021-12-16 | Buy |
Properties
Melting point :122-125°C
Boiling point :657.5±55.0 °C(Predicted)
Density :0.962
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
pka :10.60±0.20(Predicted)
color :White to Pale Beige
Stability :Hygroscopic
Major Application :pharmaceutical
InChI :InChI=1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2
InChIKey :YIQPUIGJQJDJOS-UHFFFAOYSA-N
SMILES :C1(CN2CCCNCCNCCCNCC2)=CC=C(CN2CCCNCCNCCCNCC2)C=C1
CAS DataBase Reference :110078-46-1
Boiling point :657.5±55.0 °C(Predicted)
Density :0.962
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
pka :10.60±0.20(Predicted)
color :White to Pale Beige
Stability :Hygroscopic
Major Application :pharmaceutical
InChI :InChI=1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2
InChIKey :YIQPUIGJQJDJOS-UHFFFAOYSA-N
SMILES :C1(CN2CCCNCCNCCCNCC2)=CC=C(CN2CCCNCCNCCCNCC2)C=C1
CAS DataBase Reference :110078-46-1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Autologous hematopoietic stem cell (HSC) transplantation, a standard treatment for hematological malignancies, such as non-Hodgkin’s lymphoma or multiple myeloma, involves collection of HSCs from the patient, chemo- or radiotherapy of the patient to eliminate malignant cells, and retransplantation of the stored HSCs.Plerixafor is a potent antagonist of the CXCR4 chemokine receptor and a first-in-class drug for stem cell mobilization. CXCR4 is specific for stromal-derived-factor-1 (SDF-1), a molecule endowed with potent chemotactic activity forlymphocytes. Because the interaction between SDF-1 and CXCR4 plays an important role in holding HSCs in the bone marrow, drugs that block the activity of CXCR4 receptor are capable of mobilizing HSCs into the bloodstream. In vitro, plerixafor potently blocks SDF-1 binding of CXCR4 and inhibits SDF-1-induced calcium flux (IC50 = 0.01-0.13 mg/mL) and chemotaxis (IC50 = 0.13 mg/mL) in several different cell types. Plerixafor, in combination with G-CSF, is specifically indicated to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin’s lymphoma and multiple myeloma.
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Suppliers and manufacturers
Beijing Yibai Biotechnology Co., Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
BOC Sciences
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED
Plerixafor
CAS:110078-46-1