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ChemicalBook >> CAS DataBase List >> Abemaciclib mesylate (LY2835219)

Abemaciclib mesylate (LY2835219)

Abemaciclib mesylate (LY2835219) price.
  • $9 - $2250
  • Product name: Abemaciclib mesylate (LY2835219)
  • CAS: 1231930-82-7
  • MF: C28H36F2N8O3S
  • MW: 602.71
  • EINECS:
  • MDL Number:MFCD25562906
  • Synonyms:2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1);N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine methanesulfonate (1:1) LY2835219;LY2835219 mesylate;Bemaciclib(salt);N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine,methanesulfonic acid;N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate;N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methyle;LY2835219 Ms salt, Abemaciclib Ms salt
73 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 1mg
  • 200mg
  • 500mg
  • 20mg
  • 10mM*1mLinDMSO(Solution)
  • 10mg
  • 250.00mg
  • 5.00g
  • 1.00g
  • 10mM*1mLinDMSO
  • 2.5mg
  • 10mM(in1mLDMSO)
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • 5g
  • 250mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • Manufactureraablocks
  • Product numberAA000K2C
  • Product description2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98%
  • Packaging10mg
  • Price$9
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000K2C
  • Product description2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98%
  • Packaging25mg
  • Price$12
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000K2C
  • Product description2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) ≥98%
  • Packaging50mg
  • Price$17
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000K2C
  • Product description2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98%
  • Packaging100mg
  • Price$22
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000K2C
  • Product description2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98%
  • Packaging250mg
  • Price$32
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000K2C
  • Product description2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98%
  • Packaging1g
  • Price$68
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000K2C
  • Product description2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98%
  • Packaging5g
  • Price$329
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10350
  • Product descriptionLY2835219 98%
  • Packaging5G
  • Price$345
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10350
  • Product descriptionLY2835219 98%
  • Packaging5G
  • Price$345
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10350
  • Product descriptionLY2835219 98%
  • Packaging1G
  • Price$100
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10350
  • Product descriptionLY2835219 98%
  • Packaging1G
  • Price$100
  • Updated2026-05-25
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-L0303-M100
  • Product descriptionLY2835219 ≥99%
  • Packaging100mg
  • Price$198
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-L0303-M250
  • Product descriptionLY2835219 ≥99%
  • Packaging250mg
  • Price$369
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-L0303-M100
  • Product descriptionLY2835219 ≥99%
  • Packaging100mg
  • Price$176
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2528AH
  • Product descriptionBemaciclib
  • Packaging250mg
  • Price$331
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1794
  • Product descriptionLY2835219
  • Packaging25mg
  • Price$100
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000K2C 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98% 10mg $9 2026-05-25 Buy
aablocks AA000K2C 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98% 25mg $12 2026-05-25 Buy
aablocks AA000K2C 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) ≥98% 50mg $17 2026-05-25 Buy
aablocks AA000K2C 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98% 100mg $22 2026-05-25 Buy
aablocks AA000K2C 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98% 250mg $32 2026-05-25 Buy
aablocks AA000K2C 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98% 1g $68 2026-05-25 Buy
aablocks AA000K2C 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 98% 5g $329 2026-05-25 Buy
ACHEMBLOCK 10350 LY2835219 98% 5G $345 2026-05-25 Buy
ACHEMBLOCK 10350 LY2835219 98% 5G $345 2026-05-27 Buy
ACHEMBLOCK 10350 LY2835219 98% 1G $100 2026-05-27 Buy
ACHEMBLOCK 10350 LY2835219 98% 1G $100 2026-05-25 Buy
Adipogen Life Sciences CDX-L0303-M100 LY2835219 ≥99% 100mg $198 2026-05-06 Buy
Adipogen Life Sciences CDX-L0303-M250 LY2835219 ≥99% 250mg $369 2026-05-06 Buy
Adipogen Life Sciences CDX-L0303-M100 LY2835219 ≥99% 100mg $176 2021-12-16 Buy
AK Scientific 2528AH Bemaciclib 250mg $331 2021-12-16 Buy
ApexBio Technology A1794 LY2835219 25mg $100 2026-05-06 Buy

Properties

storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml).
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
CAS DataBase Reference :1231930-82-7

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 (CDK4) and CDK6 (IC50s = 2 and 10 nM, respectively). Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds.

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