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ChemicalBook >> CAS DataBase List >> Panobinostat

Panobinostat

Panobinostat price.
  • $10 - $4735.5
  • Product name: Panobinostat
  • CAS: 404950-80-7
  • MF: C21H23N3O2
  • MW: 349.43
  • EINECS:803-814-1
  • MDL Number:MFCD09833242
  • Synonyms:(E)-N-HYDROXY-3-(4-{[2-(2-METHYL-1H-INDOL-3-YL)-ETHYLAMINO]-METHYL}-PHENYL)-ACRYLAMIDE;N-Hydroxy-3-[4-[2-(2-methyl-1H-indol-3-yl)ethylaminomethyl]phenyl]-2(E)-propenamide;LBH-589/Panobinostat;LBH-589;PANOBINOSTAT;2-Propenamide, N-hydroxy-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)-, (2E)-;NVP-LBH589;Panobinostat (LBH589)
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  • aablocks
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  • Matrix Scientific
  • TCI Chemical
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Package
  • EvaluationSample
  • 1unit
  • 1mg
  • 10mM(in 1mL DMSO)
  • 5mg
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  • 25mg
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  • 10mM*1mLinDMSO
  • 10mM(in1mLDMSO)
  • 100.00mg
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  • 500MG
  • 1.00g
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  • Manufactureraablocks
  • Product numberAA0038OK
  • Product description(E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98%
  • Packaging1mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0038OK
  • Product description(E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98%
  • Packaging10mg
  • Price$22
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0038OK
  • Product description(E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98%
  • Packaging25mg
  • Price$33
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0038OK
  • Product description(E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98%
  • Packaging100mg
  • Price$72
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0038OK
  • Product description(E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98%
  • Packaging250mg
  • Price$119
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0038OK
  • Product description(E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98%
  • Packaging1g
  • Price$305
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0038OK
  • Product description(E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98%
  • Packaging5g
  • Price$1096
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberL13155
  • Product descriptionPanobinostat 98%
  • Packaging5G
  • Price$605
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL13155
  • Product descriptionPanobinostat 98%
  • Packaging1G
  • Price$200
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL13155
  • Product descriptionPanobinostat 98%
  • Packaging100MG
  • Price$45
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product numberSYN5746
  • Product descriptionLBH-589
  • Packaging10mg
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045863
  • Product descriptionLBH-589 95.00%
  • Packaging500MG
  • Price$4735.5
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat(LBH589)
  • Packaging500mg
  • Price$440
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat (LBH589)
  • Packaging200mg
  • Price$215
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat (LBH589)
  • Packaging500mg
  • Price$377
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8178
  • Product descriptionPanobinostat(LBH589)
  • Packaging200mg
  • Price$270
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0038OK (E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98% 1mg $10 2026-05-28 Buy
aablocks AA0038OK (E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98% 10mg $22 2026-05-28 Buy
aablocks AA0038OK (E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98% 25mg $33 2026-05-28 Buy
aablocks AA0038OK (E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98% 100mg $72 2026-05-28 Buy
aablocks AA0038OK (E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98% 250mg $119 2026-05-28 Buy
aablocks AA0038OK (E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98% 1g $305 2026-05-28 Buy
aablocks AA0038OK (E)-N-Hydroxy-3-(4-(((2-(2-Methyl-1H-Indol-3-Yl)Ethyl)Amino)Methyl)Phenyl)Acrylamide 98% 5g $1096 2026-05-28 Buy
ACHEMBLOCK L13155 Panobinostat 98% 5G $605 2026-05-27 Buy
ACHEMBLOCK L13155 Panobinostat 98% 1G $200 2026-05-27 Buy
ACHEMBLOCK L13155 Panobinostat 98% 100MG $45 2026-05-27 Buy
AK Scientific SYN5746 LBH-589 10mg $142 2021-12-16 Buy
American Custom Chemicals Corporation API0045863 LBH-589 95.00% 500MG $4735.5 2021-12-16 Buy
ApexBio Technology A8178 Panobinostat(LBH589) 500mg $440 2021-12-16 Buy
ApexBio Technology A8178 Panobinostat (LBH589) 200mg $215 2026-05-06 Buy
ApexBio Technology A8178 Panobinostat (LBH589) 500mg $377 2026-05-06 Buy
ApexBio Technology A8178 Panobinostat(LBH589) 200mg $270 2021-12-16 Buy

Properties

Melting point :114-117C
Density :1.241±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under Inert Atmosphere
solubility :Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
form :solid
pka :8.71±0.23(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChI :InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+
InChIKey :FPOHNWQLNRZRFC-ZHACJKMWSA-N
SMILES :C(NO)(=O)/C=C/C1=CC=C(CNCCC2C3=C(NC=2C)C=CC=C3)C=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Panobinostat is a potent inhibitor of all histone deacetylases (HDACs), with Ki values ranging from 0.6 to 31 nM for HDAC1-11. Through this action, it leads to acetylation of a range of cellular proteins, resulting in cell cycle arrest and apoptosis in cancer cells. It has potential applications in several different forms of cancer as well as in spinal muscular atrophy and HIV therapy.

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