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ChemicalBook >> CAS DataBase List >> Pioglitazone

Pioglitazone

Pioglitazone price.
  • $8 - $1963.5
  • Product name: Pioglitazone
  • CAS: 111025-46-8
  • MF: C19H20N2O3S
  • MW: 356.44
  • EINECS:601-029-7
  • MDL Number:MFCD00865504
  • Synonyms:Pioglitazone;5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione;PIOGLITAZONE HCL(5-[[4-[2-(5-ETHYLPYRIDIN-2-YL)ETHOXY]PHENYL]METHYL]THIAZOLIDINE-2,4-DIONE, HCL);PINEPOLLEN;5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl]thiazolidine-2,4-dione;Pioglitazone (Actos);2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]Methyl]-;Pioglitazone 5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
111 prices
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  • aablocks
  • AccelPharmtech
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mg
  • 10mM(in1mLDMSO)
  • 1mg
  • 5mg
  • 10mM*1mLinDMSO(Solution)
  • 1mlx10mM(inDMSO)
  • 25mg
  • 50mg
  • 100mg
  • 250mg
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  • 1g
  • 2g
  • 5g
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  • 50g
  • 100g
  • 50 mg
  • Manufactureraablocks
  • Product numberAA00HBPV
  • Product descriptionPioglitazone ≥98%
  • Packaging10mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00HBPV
  • Product descriptionPioglitazone 99%(HPLC)
  • Packaging1mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00HBPV
  • Product descriptionPioglitazone ≥98%
  • Packaging50mg
  • Price$16
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00HBPV
  • Product descriptionPioglitazone ≥98%
  • Packaging250mg
  • Price$20
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00HBPV
  • Product descriptionPioglitazone ≥98%
  • Packaging1g
  • Price$50
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00HBPV
  • Product descriptionPioglitazone 95%
  • Packaging10g
  • Price$318
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00HBPV
  • Product descriptionPioglitazone ≥98%
  • Packaging5g
  • Price$170
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00HBPV
  • Product descriptionPioglitazone 95%
  • Packaging100g
  • Price$1342
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00HBPV
  • Product descriptionPioglitazone 95%
  • Packaging25g
  • Price$540
  • Updated2026-05-28
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  • ManufacturerAccelPharmtech
  • Product numberTR00004
  • Product descriptionPioglitazone 95%
  • Packaging5g
  • Price$237
  • Updated2026-05-21
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  • ManufacturerAccelPharmtech
  • Product numberTR000045g
  • Product descriptionPioglitazone 95%
  • Packaging
  • Price$237
  • Updated2026-05-21
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  • ManufacturerAccelPharmtech
  • Product numberAT5958
  • Product descriptionPioglitazone 98%
  • Packaging1G
  • Price$50
  • Updated2021-12-16
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  • ManufacturerAccelPharmtech
  • Product numberTR00004
  • Product descriptionPioglitazone 95%
  • Packaging1g
  • Price$87
  • Updated2026-05-21
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  • ManufacturerAccelPharmtech
  • Product numberTR000041g
  • Product descriptionPioglitazone 95%
  • Packaging
  • Price$87
  • Updated2026-05-21
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  • ManufacturerAccelPharmtech
  • Product numberAT5958
  • Product descriptionPioglitazone 98%
  • Packaging5G
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0067-M025
  • Product descriptionPioglitazone ≥98%(HPLC)
  • Packaging25mg
  • Price$80
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00HBPV Pioglitazone ≥98% 10mg $10 2026-05-28 Buy
aablocks AA00HBPV Pioglitazone 99%(HPLC) 1mg $10 2026-05-28 Buy
aablocks AA00HBPV Pioglitazone ≥98% 50mg $16 2026-05-28 Buy
aablocks AA00HBPV Pioglitazone ≥98% 250mg $20 2026-05-28 Buy
aablocks AA00HBPV Pioglitazone ≥98% 1g $50 2026-05-28 Buy
aablocks AA00HBPV Pioglitazone 95% 10g $318 2026-05-28 Buy
aablocks AA00HBPV Pioglitazone ≥98% 5g $170 2026-05-28 Buy
aablocks AA00HBPV Pioglitazone 95% 100g $1342 2026-05-28 Buy
aablocks AA00HBPV Pioglitazone 95% 25g $540 2026-05-28 Buy
AccelPharmtech TR00004 Pioglitazone 95% 5g $237 2026-05-21 Buy
AccelPharmtech TR000045g Pioglitazone 95% $237 2026-05-21 Buy
AccelPharmtech AT5958 Pioglitazone 98% 1G $50 2021-12-16 Buy
AccelPharmtech TR00004 Pioglitazone 95% 1g $87 2026-05-21 Buy
AccelPharmtech TR000041g Pioglitazone 95% $87 2026-05-21 Buy
AccelPharmtech AT5958 Pioglitazone 98% 5G $180 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-0067-M025 Pioglitazone ≥98%(HPLC) 25mg $80 2026-05-06 Buy

Properties

Melting point :183-184 C
Boiling point :575.4±45.0 °C(Predicted)
Density :1.260±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly, Heated)
pka :6.35±0.50(Predicted)
form :White to off-white solid.
color :White to Off-White
Henry's Law Constant :5.8×106 mol/(m3Pa) at 25℃, HSDB (2015)
InChI :InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)
InChIKey :HYAFETHFCAUJAY-UHFFFAOYSA-N
SMILES :S1C(CC2=CC=C(OCCC3=NC=C(CC)C=C3)C=C2)C(=O)NC1=O
IARC :2A (Vol. 108) 2016

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Thiazolidinediones (TZDs) are a group of structurally related PPARγ agonists with anti-diabetic actions in vivo. Rosiglitazone (BRL49653) is a prototypical TZD and has served as a reference compound for this class of PPARγ ligands. Pioglitazone is a closely related TZD which also selectively activates PPARγ-1. Pioglitazone is about one tenth as potent as rosiglitazone, with an EC50 of about 500-600 nM for both human and mouse PPARγ. In a transactivation assay using COS-1 cells transfected with full length human PPARα and RXRα, pioglitazone and rosiglitazone exhibit low level activation of PPARα at 1 μM and 5.4- and 4.2-fold activation, respectively, at a concentration of 10 μM.

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