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ChemicalBook >> CAS DataBase List >> Ritlecitinib

Ritlecitinib

Ritlecitinib price.
  • $47 - $2500
  • Product name: Ritlecitinib
  • CAS: 1792180-81-4
  • MF: C15H19N5O
  • MW: 285.34
  • EINECS:210-077-2
  • MDL Number:MFCD31697544
  • Synonyms:1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one;1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2;PF-06651600;PF 06651600;PF06651600;1-[(2S,5R)-2-methyl-5(7H-pyrrolo[2,3-d]pyrimidine-4-ylamino)-1-piperidinly]-2-propen-1-one malonate,PF06651600;2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-;1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one;Ritlecitinib;Ritlecitinib (PF-06651600)
42 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • Alichem
  • American Custom Chemicals Corporation
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Usbiological
Package
  • 2mg
  • 10mM*1mLinDMSO
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250MG
  • 500mg
  • 1g
  • Manufactureraablocks
  • Product numberAA0026RT
  • Product descriptionRitlecitinib 95
  • Packaging2mg
  • Price$47
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0026RT
  • Product descriptionRitlecitinib 95%
  • Packaging100mg
  • Price$50
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0026RT
  • Product descriptionRitlecitinib 95%
  • Packaging1g
  • Price$467
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX193539
  • Product description1-[(2S,5R)-5-[[7H-Pyrrolo[2,3-d]-4-pyrimidinyl]amino]-2-methyl-1-piperidyl]-2-propen-1-one 95.00%
  • Packaging250MG
  • Price$120
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX193539
  • Product description1-[(2S,5R)-5-[[7H-Pyrrolo[2,3-d]-4-pyrimidinyl]amino]-2-methyl-1-piperidyl]-2-propen-1-one 95.00%
  • Packaging1G
  • Price$325
  • Updated2026-05-27
  • Buy
  • ManufacturerAlichem
  • Product number1792180814
  • Product description1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one
  • Packaging100mg
  • Price$829.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002534
  • Product descriptionPF-06651600 95.00%
  • Packaging5MG
  • Price$457.78
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberBP168506
  • Product descriptionPF 06651600
  • Packaging50mg
  • Price$571
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberBP168506
  • Product descriptionPF 06651600
  • Packaging25mg
  • Price$357
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberBP168506
  • Product descriptionPF 06651600
  • Packaging10mg
  • Price$250
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberBP168506
  • Product descriptionPF 06651600
  • Packaging2mg
  • Price$250
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberBP168506
  • Product descriptionPF 06651600
  • Packaging5mg
  • Price$250
  • Updated2026-06-04
  • Buy
  • ManufacturerCayman Chemical
  • Product number21054
  • Product descriptionPF-06651600 ≥95%
  • Packaging10mg
  • Price$91
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number21054
  • Product descriptionPF-06651600 ≥95%
  • Packaging50mg
  • Price$429
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number21054
  • Product descriptionPF-06651600 ≥95%
  • Packaging100mg
  • Price$767
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number21054
  • Product descriptionPF-06651600 ≥95%
  • Packaging250mg
  • Price$1241
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0026RT Ritlecitinib 95 2mg $47 2026-05-28 Buy
aablocks AA0026RT Ritlecitinib 95% 100mg $50 2026-05-28 Buy
aablocks AA0026RT Ritlecitinib 95% 1g $467 2026-05-28 Buy
ACHEMBLOCK X193539 1-[(2S,5R)-5-[[7H-Pyrrolo[2,3-d]-4-pyrimidinyl]amino]-2-methyl-1-piperidyl]-2-propen-1-one 95.00% 250MG $120 2026-05-27 Buy
ACHEMBLOCK X193539 1-[(2S,5R)-5-[[7H-Pyrrolo[2,3-d]-4-pyrimidinyl]amino]-2-methyl-1-piperidyl]-2-propen-1-one 95.00% 1G $325 2026-05-27 Buy
Alichem 1792180814 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one 100mg $829.25 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002534 PF-06651600 95.00% 5MG $457.78 2021-12-16 Buy
Biosynth BP168506 PF 06651600 50mg $571 2026-06-04 Buy
Biosynth BP168506 PF 06651600 25mg $357 2026-06-04 Buy
Biosynth BP168506 PF 06651600 10mg $250 2026-06-04 Buy
Biosynth BP168506 PF 06651600 2mg $250 2026-06-04 Buy
Biosynth BP168506 PF 06651600 5mg $250 2026-06-04 Buy
Cayman Chemical 21054 PF-06651600 ≥95% 10mg $91 2026-04-30 Buy
Cayman Chemical 21054 PF-06651600 ≥95% 50mg $429 2026-04-30 Buy
Cayman Chemical 21054 PF-06651600 ≥95% 100mg $767 2026-04-30 Buy
Cayman Chemical 21054 PF-06651600 ≥95% 250mg $1241 2026-04-30 Buy

Properties

Density :1.272±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO:100.0(Max Conc. mg/mL);350.4(Max Conc. mM)
H2O:5.0(Max Conc. mg/mL);17.5(Max Conc. mM) pka :13.03±0.50(Predicted)
form :powder
color :white to beige
Water Solubility :H2O: 5mg/mL, clear (warmed)
InChI :InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
InChIKey :CBRJPFGIXUFMTM-WDEREUQCSA-N
SMILES :C(N1C[C@H](NC2N=CN=C3NC=CC3=2)CC[C@@H]1C)(=O)C=C

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ritlecitinib, a dual JAK3/TEC inhibitor, was granted FDA breakthrough status for treating alopecia areata (autoimmune-induced hair loss) in September 2018. Promising phase 3 trial results in alopecia areata were reported by Pfizer in August 2021, placing it in competition with Lilly/Incyte’s Olumiant. It is also used in clinical studies to treat vitiligo, rheumatoid arthritis, Crohn’s disease, and ulcerative colitis. Ritlecitinib achieved high JAK3 selectivity via covalent interaction with a unique cysteine residue (Cys909) in the catalytic domain.

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