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ChemicalBook >> CAS DataBase List >> 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID

2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID

2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID price.
  • $8 - $2810
  • Product name: 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID
  • CAS: 321674-73-1
  • MF: C21H17NO3
  • MW: 331.36
  • EINECS:
  • MDL Number:MFCD11112195
  • Synonyms:2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID;BIBR 1532;2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoicacid;2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl]amino]benzoic acid;(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid;BIBR 1532, >=98%;BIBR 1532;BIBR-1532;CS-1061
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  • aablocks
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  • 10mM(in 1mL DMSO)
  • 5G
  • 10mM*1mLinDMSO
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA00C6C6
  • Product description(E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99%
  • Packaging50mg
  • Price$69
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6C6
  • Product description(E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99%
  • Packaging100mg
  • Price$117
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6C6
  • Product description(E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99%
  • Packaging250mg
  • Price$198
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6C6
  • Product description(E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99%
  • Packaging1g
  • Price$553
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6C6
  • Product description(E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99%
  • Packaging25mg
  • Price$42
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6C6
  • Product description(E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99%
  • Packaging10mg
  • Price$27
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6C6
  • Product description(E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99%
  • Packaging5mg
  • Price$19
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6C6
  • Product description(E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99%
  • Packaging1mg
  • Price$8
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberQ65504
  • Product description(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid 98%
  • Packaging5G
  • Price$2810
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberQ65504
  • Product description(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid 98%
  • Packaging250MG
  • Price$255
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberQ65504
  • Product description(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid 98%
  • Packaging1G
  • Price$755
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product numberX7524
  • Product description(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoicacid
  • Packaging10mg
  • Price$170
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000875
  • Product descriptionBIBR-1532 95.00%
  • Packaging10MG
  • Price$709.46
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000875
  • Product descriptionBIBR-1532 95.00%
  • Packaging1MG
  • Price$135.45
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000875
  • Product descriptionBIBR-1532 95.00%
  • Packaging50MG
  • Price$1267.33
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA1945
  • Product descriptionBIBR1532
  • Packaging10mM(in 1mL DMSO)
  • Price$99
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C6C6 (E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99% 50mg $69 2026-05-28 Buy
aablocks AA00C6C6 (E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99% 100mg $117 2026-05-28 Buy
aablocks AA00C6C6 (E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99% 250mg $198 2026-05-28 Buy
aablocks AA00C6C6 (E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99% 1g $553 2026-05-28 Buy
aablocks AA00C6C6 (E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99% 25mg $42 2026-05-28 Buy
aablocks AA00C6C6 (E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99% 10mg $27 2026-05-28 Buy
aablocks AA00C6C6 (E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99% 5mg $19 2026-05-28 Buy
aablocks AA00C6C6 (E)-2-(3-(Naphthalen-2-Yl)But-2-Enamido)Benzoic Acid 99% 1mg $8 2026-05-28 Buy
ACHEMBLOCK Q65504 (E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid 98% 5G $2810 2026-05-27 Buy
ACHEMBLOCK Q65504 (E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid 98% 250MG $255 2026-05-27 Buy
ACHEMBLOCK Q65504 (E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid 98% 1G $755 2026-05-27 Buy
AK Scientific X7524 (E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoicacid 10mg $170 2021-12-16 Buy
American Custom Chemicals Corporation INB0000875 BIBR-1532 95.00% 10MG $709.46 2021-12-16 Buy
American Custom Chemicals Corporation INB0000875 BIBR-1532 95.00% 1MG $135.45 2021-12-16 Buy
American Custom Chemicals Corporation INB0000875 BIBR-1532 95.00% 50MG $1267.33 2021-12-16 Buy
ApexBio Technology A1945 BIBR1532 10mM(in 1mL DMSO) $99 2021-12-16 Buy

Properties

Melting point :>173oC (dec.)
Boiling point :600.6±48.0 °C(Predicted)
Density :1.284
storage temp. :Store at RT
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :3.46±0.36(Predicted)
form :Solid
color :White to Off-White
InChI :InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+
InChIKey :PGFQXGLPJUCTOI-WYMLVPIESA-N
SMILES :C(O)(=O)C1=CC=CC=C1NC(=O)/C=C(/C1=CC=C2C(=C1)C=CC=C2)\C

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

BIBR 1532 is a mixed-type non-competitive inhibitor of telomerase (IC50 = 93 nM) that has little effect on several mammalian DNA and RNA polymerases, bacterial DNA helicase, or HIV-1 reverse transcriptase. It specifically targets the telomerase reverse transcriptase catalytic subunit, TERT. Through its effects on telomerase, BIBR 1532 induces senescence or apoptosis in cancer cells. Apoptosis in triple negative breast cancer cells induced by BIBR 1532 is potentiated by glucose restriction.

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