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ChemicalBook >> CAS DataBase List >> Silybin

Silybin

$5 - $1631
Product name: Silybin
CAS: 22888-70-6
MF: C25H22O10
MW: 482.44
EINECS:245-302-5
MDL Number:MFCD00872186
Synonyms:Silybin-A ,98%;Silybin (50 mg);Silybin, 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin;Silybin，Silymarin;(2R)-2α-[[(2R,3R)-2,3-Dihydro-3β-(4-hydroxy-3-methoxyphenyl)-2α-(hydroxymethyl)-1,4-benzodioxin]-6-yl]-2,3-dihydro-3β,5,7-trihydroxy-4H-1-benzopyran-4-one;(2R,3R)-2-[[(2R,3R)-2,3-Dihydro-3β-(4-hydroxy-3-methoxyphenyl)-2α-(hydroxymethyl)-1,4-benzodioxin]-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one;Flavobion;silliver

Price74 Properties Safety Information Description

74 prices

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aablocks
Adipogen Life Sciences
AHH
Ambeed
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Axon Medchem
Biorbyt Ltd
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
JR MediChem
Sigma-Aldrich
TRC
Usbiological

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5mg
10mg
20mg
50mg
500mg
1000mg
5000mg
5g
10000mg
50000mg
50g
1mg
25mg
100mg
1g
2g
10mM(in1mLDMSO)
10g
500g
25g
100g
10mM(in 1mL DMSO)

Manufactureraablocks
Product numberAA00I4FF
Product description(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%
Packaging5g
Price$46
Updated2026-05-29
Buy

Manufactureraablocks
Product numberAA00I4FF
Product description(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%
Packaging10g
Price$87
Updated2026-05-29
Buy

Manufactureraablocks
Product numberAA00I4FF
Product description(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%
Packaging1g
Price$18
Updated2026-05-29
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Manufactureraablocks
Product numberAA00I4FF
Product description(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%
Packaging1mg
Price$8
Updated2026-05-29
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ManufacturerAdipogen Life Sciences
Product numberCDX-S0276-G100
Product descriptionSilibinin ≥98%(HPLC)
Packaging100g
Price$579
Updated2026-05-06
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ManufacturerAdipogen Life Sciences
Product numberCDX-S0276-G010
Product descriptionSilibinin ≥98%(HPLC)
Packaging10g
Price$73
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberCDX-S0276-G010
Product descriptionSilibinin ≥98%(HPLC)
Packaging10g
Price$65
Updated2021-12-16
Buy

ManufacturerAHH
Product numberAPI-1488
Product descriptionSilybin 98%
Packaging500g
Price$700
Updated2021-12-16
Buy

ManufacturerAHH
Product numberAPI-1488
Product descriptionSilybin 97%
Packaging500g
Price$700
Updated2026-05-26
Buy

ManufacturerAmbeed
Product numberA177518
Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
Packaging25g
Price$275
Updated2021-12-16
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ManufacturerAmbeed
Product numberA177518
Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
Packaging5g
Price$66
Updated2021-12-16
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ManufacturerAmbeed
Product numberA177518
Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
Packaging10g
Price$76
Updated2021-12-16
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ManufacturerAmbeed
Product numberA177518
Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
Packaging25mg
Price$5
Updated2021-12-16
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ManufacturerAmbeed
Product numberA177518
Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
Packaging100mg
Price$6
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA177518
Product description(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%
Packaging1g
Price$12
Updated2021-12-16
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ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0026191
Product descriptionSILYBIN 95.00%
Packaging5G
Price$827.1
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00I4FF	(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%	5g	$46	2026-05-29	Buy
aablocks	AA00I4FF	(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%	10g	$87	2026-05-29	Buy
aablocks	AA00I4FF	(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%	1g	$18	2026-05-29	Buy
aablocks	AA00I4FF	(2R,3R)-2-[(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one 98%	1mg	$8	2026-05-29	Buy
Adipogen Life Sciences	CDX-S0276-G100	Silibinin ≥98%(HPLC)	100g	$579	2026-05-06	Buy
Adipogen Life Sciences	CDX-S0276-G010	Silibinin ≥98%(HPLC)	10g	$73	2026-05-06	Buy
Adipogen Life Sciences	CDX-S0276-G010	Silibinin ≥98%(HPLC)	10g	$65	2021-12-16	Buy
AHH	API-1488	Silybin 98%	500g	$700	2021-12-16	Buy
AHH	API-1488	Silybin 97%	500g	$700	2026-05-26	Buy
Ambeed	A177518	(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%	25g	$275	2021-12-16	Buy
Ambeed	A177518	(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%	5g	$66	2021-12-16	Buy
Ambeed	A177518	(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%	10g	$76	2021-12-16	Buy
Ambeed	A177518	(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%	25mg	$5	2021-12-16	Buy
Ambeed	A177518	(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%	100mg	$6	2021-12-16	Buy
Ambeed	A177518	(2R,3R)-3,5,7-Trihydroxy-2-((2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)chroman-4-one 98%	1g	$12	2021-12-16	Buy
American Custom Chemicals Corporation	API0026191	SILYBIN 95.00%	5G	$827.1	2021-12-16	Buy

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Properties

Melting point :164-174°C
Boiling point :793.0±60.0 °C(Predicted)
alpha :D20 +11° (c = 0.25 in acetone + alcohol)
Density :1.527±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Acetone (Sparingly), DMSO, Methano (Sparingly)
form :Solid
pka :pKa 6.42±0.04 (Uncertain)
color :Pale Yellow
Water Solubility :54mg/L(24.99 ºC)
Merck :13,8607
Stability :Stable. Incompatible with strong oxidizing agents, strong bases.
Cosmetics Ingredients Functions :SKIN CONDITIONING
InChIKey :SEBFKMXJBCUCAI-HKTJVKLFSA-N
SMILES :C([C@H]1OC2=CC=C([C@@H]3[C@H](C(C4=C(C=C(C=C4O3)O)O)=O)O)C=C2O[C@@H]1C1C=CC(=C(C=1)OC)O)O
LogP :4.232 (est)
CAS DataBase Reference :22888-70-6(CAS DataBase Reference)

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501

Precautionary statements:

P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501	Dispose of contents/container to..…

Description

Silybin is an inhibitor of a wide variety of proteins, many of which are heavily involved in xenobiotic efflux and metabolism. Silybin is an inhibitor of P-glycoprotein-mediated cellular efflux and also inhibits xenobiotic oxidation by the CYP (cytochrome P450) superfamily of enzymes. This helps to contribute the apoptotic activity of this compound, which has been shown to be effective against a wide variety of cancer cell lines. Silybin is an inhibitor of 5-LO.

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Suppliers and manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

$1.00
Silibinin CAS:22888-70-6

Wuhan Fortuna Chemical Co., Ltd

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ZhenYiBio Technology Inc

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Henan Fengda Chemical Co., Ltd

$2.00
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Shaanxi Xianhe Biotech Co., Ltd

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Aurora Industry Co., Ltd.

$10.00
Milk Thistle Extract CAS:22888-70-6

Hebei Zhuanglai Chemical Trading Co Ltd

$150.00
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Henan Tianfu Chemical Co.,Ltd.

Nanjing Finetech Chemical Co., Ltd.

Shanghai Zheyan Biotech Co., Ltd.

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Silybin

Properties

Safety Information

Description

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