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ChemicalBook >> CAS DataBase List >> TAK-733

TAK-733

TAK-733 price.
  • $21 - $4171.86
  • Product name: TAK-733
  • CAS: 1035555-63-5
  • MF: C17H15F2IN4O4
  • MW: 504.23
  • EINECS:
  • MDL Number:MFCD24386349
  • Synonyms:TAK-733;TAK-733/TAK733;(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione;(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione TAK 733;(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrim;CS-547;3-[(2r)-2,3-dihydroxypropyl]-6-fluoro-5-(2-fluoro-4-iodoanilino)-8-methylpyrido[2,3-d]pyrimidine-4,7-dione;Pyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione, 3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methyl-
59 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
Package
  • 2mg
  • 10mM(1mLinDMSO)
  • 500μg
  • 50.00mg
  • 250mg
  • 1000mg
  • 10mM*1mLinDMSO
  • 1g
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 200MG
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA008TH1
  • Product description(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione ≥96%
  • Packaging1mg
  • Price$21
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TH1
  • Product description(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione 98%
  • Packaging10mg
  • Price$119
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TH1
  • Product description(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione ≥96%
  • Packaging5mg
  • Price$76
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TH1
  • Product description(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione 98%
  • Packaging25mg
  • Price$178
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA008TH1
  • Product description(R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione ≥96%
  • Packaging50mg
  • Price$349
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230559
  • Product descriptionTAK-733 98%
  • Packaging25MG
  • Price$285
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY230559
  • Product descriptionTAK-733 98%
  • Packaging100MG
  • Price$830
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010228
  • Product descriptionTAK-733 95.00%
  • Packaging200MG
  • Price$4171.86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010228
  • Product descriptionTAK-733 95.00%
  • Packaging5MG
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1621
  • Product descriptionTAK-733
  • Packaging50mg
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1621
  • Product descriptionTAK-733
  • Packaging50mg
  • Price$680
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1621
  • Product descriptionTAK-733
  • Packaging10mg
  • Price$225
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1621
  • Product descriptionTAK-733
  • Packaging5mg
  • Price$120
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1621
  • Product descriptionTAK-733
  • Packaging10mM(in1mLDMSO)
  • Price$125
  • Updated2026-05-06
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0162
  • Product descriptionTAK-733
  • Packaging2mg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0162
  • Product descriptionTAK-733
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008TH1 (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione ≥96% 1mg $21 2026-05-28 Buy
aablocks AA008TH1 (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione 98% 10mg $119 2026-05-28 Buy
aablocks AA008TH1 (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione ≥96% 5mg $76 2026-05-28 Buy
aablocks AA008TH1 (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione 98% 25mg $178 2026-05-28 Buy
aablocks AA008TH1 (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-((2-fluoro-4-iodophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione ≥96% 50mg $349 2026-05-28 Buy
ACHEMBLOCK Y230559 TAK-733 98% 25MG $285 2026-05-27 Buy
ACHEMBLOCK Y230559 TAK-733 98% 100MG $830 2026-05-27 Buy
American Custom Chemicals Corporation API0010228 TAK-733 95.00% 200MG $4171.86 2021-12-16 Buy
American Custom Chemicals Corporation API0010228 TAK-733 95.00% 5MG $330 2021-12-16 Buy
ApexBio Technology B1621 TAK-733 50mg $680 2021-12-16 Buy
ApexBio Technology B1621 TAK-733 50mg $680 2026-05-06 Buy
ApexBio Technology B1621 TAK-733 10mg $225 2026-05-06 Buy
ApexBio Technology B1621 TAK-733 5mg $120 2026-05-06 Buy
ApexBio Technology B1621 TAK-733 10mM(in1mLDMSO) $125 2026-05-06 Buy
Apolloscientific BISN0162 TAK-733 2mg $102 2021-12-16 Buy
Apolloscientific BISN0162 TAK-733 5mg $160 2021-12-16 Buy

Properties

Boiling point :530.5±60.0 °C(Predicted)
Density :1.91±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥25.2 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :13.72±0.20(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. Phase 1.

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