Tucatinib
|
- $9 - $2500
- Product name: Tucatinib
- CAS: 937263-43-9
- MF: C26H24N8O2
- MW: 480.52
- EINECS:200-001-8
- MDL Number:MFCD22380467
- Synonyms:ONT-380);N4-(4-([1;N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine;Irbinitinib(ARRY380);(R)-N6-(4-Methyl-4;5-dihydrooxazol-2-yl)-N4-(3-Methyl-4-(thiazol-2-ylMethoxy)phenyl)quinazoline-4;6-diaMine;4-diMethyl-4
44 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- AvaChem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
- Usbiological
Package
- 2.5mg
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100.00mg
- 100mg
- 250.00mg
- 250mg
- 500mg
- 1.00g
- 1g
- 5g
- 10g
- Manufactureraablocks
- Product numberAA00GTX3
- Product description4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98%
- Packaging1mg
- Price$9
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTX3
- Product description4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98%
- Packaging10mg
- Price$18
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTX3
- Product description4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98%
- Packaging25mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTX3
- Product description4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98%
- Packaging100mg
- Price$63
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTX3
- Product description4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98%
- Packaging5g
- Price$998
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTX3
- Product description4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98%
- Packaging1g
- Price$286
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GTX3
- Product description4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98%
- Packaging250mg
- Price$106
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22591
- Product descriptionIrbinitinib 98%
- Packaging1G
- Price$320
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22591
- Product descriptionIrbinitinib 98%
- Packaging5G
- Price$1050
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22591
- Product descriptionIrbinitinib 98%
- Packaging100MG
- Price$70
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number8979DH
- Product descriptionTucatinib
- Packaging25mg
- Price$590
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number5201
- Product descriptionTucatinib; Irbinitinib 99%
- Packaging10mg
- Price$85
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number5201
- Product descriptionTucatinib; Irbinitinib 99%
- Packaging5mg
- Price$55
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number5201
- Product descriptionTucatinib; Irbinitinib 99%
- Packaging25mg
- Price$145
- Updated2026-05-22
- Buy
- ManufacturerBiosynth
- Product numberBT177688
- Product descriptionTucatinib
- Packaging100mg
- Price$1125
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberBT177688
- Product descriptionTucatinib
- Packaging25mg
- Price$375
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GTX3 | 4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98% | 1mg | $9 | 2026-05-28 | Buy |
| aablocks | AA00GTX3 | 4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98% | 10mg | $18 | 2026-05-28 | Buy |
| aablocks | AA00GTX3 | 4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98% | 25mg | $27 | 2026-05-28 | Buy |
| aablocks | AA00GTX3 | 4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98% | 100mg | $63 | 2026-05-28 | Buy |
| aablocks | AA00GTX3 | 4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98% | 5g | $998 | 2026-05-28 | Buy |
| aablocks | AA00GTX3 | 4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98% | 1g | $286 | 2026-05-28 | Buy |
| aablocks | AA00GTX3 | 4,6-Quinazolinediamine, N6-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]- 98% | 250mg | $106 | 2026-05-28 | Buy |
| ACHEMBLOCK | M22591 | Irbinitinib 98% | 1G | $320 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22591 | Irbinitinib 98% | 5G | $1050 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22591 | Irbinitinib 98% | 100MG | $70 | 2026-05-27 | Buy |
| AK Scientific | 8979DH | Tucatinib | 25mg | $590 | 2021-12-16 | Buy |
| AvaChem | 5201 | Tucatinib; Irbinitinib 99% | 10mg | $85 | 2026-05-22 | Buy |
| AvaChem | 5201 | Tucatinib; Irbinitinib 99% | 5mg | $55 | 2026-05-22 | Buy |
| AvaChem | 5201 | Tucatinib; Irbinitinib 99% | 25mg | $145 | 2026-05-22 | Buy |
| Biosynth | BT177688 | Tucatinib | 100mg | $1125 | 2026-06-04 | Buy |
| Biosynth | BT177688 | Tucatinib | 25mg | $375 | 2026-06-04 | Buy |
Properties
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:1.0(Max Conc. mg/mL);2.08(Max Conc. mM)
DMSO:49.0(Max Conc. mg/mL);101.97(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.69(Max Conc. mM) form :A crystalline solid
pka :6.61±0.70(Predicted)
color :White to yellow
InChIKey :SDEAXTCZPQIFQM-UHFFFAOYSA-N
SMILES :N1=C2C(C=C(NC3=NC(C)(C)CO3)C=C2)=C(NC2=CC=C(OC3C=CN4N=CN=C4C=3)C(C)=C2)N=C1
storage temp. :Store at -20°C
solubility :DMF:1.0(Max Conc. mg/mL);2.08(Max Conc. mM)
DMSO:49.0(Max Conc. mg/mL);101.97(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.69(Max Conc. mM) form :A crystalline solid
pka :6.61±0.70(Predicted)
color :White to yellow
InChIKey :SDEAXTCZPQIFQM-UHFFFAOYSA-N
SMILES :N1=C2C(C=C(NC3=NC(C)(C)CO3)C=C2)=C(NC2=CC=C(OC3C=CN4N=CN=C4C=3)C(C)=C2)N=C1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Tucatinib is also known as ARRY-380 or Irbinitinib. ARRY-380 is an orally inhibitor of human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. It selectively binds to and inhibits the phosphorylation of ErbB-2, which may prevent the activation of ErbB-2 signal transduction pathways, resulting in growth inhibition and death of ErbB-2-expressing tumor cells. ErbB-2 is overexpressed in a variety of cancers and plays an important role in cellular proliferation and differentiation. Therefore, ARRY-380 may be an alternative treatmentmethod for the treatment of HER2+ cancers.More related product prices
AZD-9291 Dacomitinib (PF299804) CO-1686 Poziotinib (HM781-36B) Neratinib EGF816 OSI-420 AG 1478 HYDROCHLORIDE AZD 3759 Genistein Olmutinib Everolimus Anastrozole XL-647 TroxerutinRelated product price
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AZD-9291
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Dacomitinib (PF299804)
$10-1703 -
CO-1686
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Suppliers and manufacturers
HangZhou RunYan Pharma Technology Co.,LTD.
Tucatinib
CAS:937263-43-9
Zhengzhou Anbu Chem Co.,Ltd
Irbinitinib
CAS:937263-43-9
Hangzhou Hyper Chemicals Limited
Zhengzhou Anhuida Chemical Co., Ltd
Suzhou ARTK Medchem Co., Ltd.
Henan Tianfu Chemical Co.,Ltd.
Nanjing Finetech Chemical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
TianYuan Pharmaceutical CO.,LTD
Shenzhen Nexconn Pharmatechs Ltd
Tucatinib
CAS:937263-43-9