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ChemicalBook >> CAS DataBase List >> Poziotinib (HM781-36B)

Poziotinib (HM781-36B)

$9 - $2841
Product name: Poziotinib (HM781-36B)
CAS: 1092364-38-9
MF: C23H21Cl2FN4O3
MW: 491.34
EINECS:
MDL Number:MFCD28044290
Synonyms:1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one;UNII-OEI6OOU6IK;1-(4-((4-((3,4-dichloro-2-fluorophenyl)aMino)-7- Methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one;1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one;poziotinib(HM-78136B);1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one Poziotinib;HM781-36B);Poziotinib(NOV120101

Price66 Properties Safety Information Description

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aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
Axon Medchem
Biosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
TRC

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10mM(1mLinDMSO)
1mg
2mg
5mg
10mg
25mg
50mg
100mg
10mM*1mLinDMSO
250mg
1g
5g

Manufactureraablocks
Product numberAA0039IJ
Product description1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%
Packaging1mg
Price$9
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0039IJ
Product description1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one ≥97%
Packaging5mg
Price$11
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0039IJ
Product description1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%
Packaging10mg
Price$19
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0039IJ
Product description1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one ≥97%
Packaging25mg
Price$41
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0039IJ
Product description1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%
Packaging100mg
Price$76
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0039IJ
Product description1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%
Packaging250mg
Price$119
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0039IJ
Product description1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%
Packaging1g
Price$396
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0039IJ
Product description1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%
Packaging5g
Price$1342
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberQ65680
Product description1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%
Packaging5G
Price$895
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberQ65680
Product description1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%
Packaging5G
Price$895
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ65680
Product description1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%
Packaging1G
Price$330
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberQ65680
Product description1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%
Packaging1G
Price$330
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ65680
Product description1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%
Packaging100MG
Price$95
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberQ65680
Product description1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%
Packaging100MG
Price$95
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberQ65680
Product description1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%
Packaging25MG
Price$40
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberQ65680
Product description1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%
Packaging25MG
Price$40
Updated2026-05-27
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA0039IJ	1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%	1mg	$9	2026-05-28	Buy
aablocks	AA0039IJ	1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one ≥97%	5mg	$11	2026-05-28	Buy
aablocks	AA0039IJ	1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%	10mg	$19	2026-05-28	Buy
aablocks	AA0039IJ	1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one ≥97%	25mg	$41	2026-05-28	Buy
aablocks	AA0039IJ	1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%	100mg	$76	2026-05-28	Buy
aablocks	AA0039IJ	1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%	250mg	$119	2026-05-28	Buy
aablocks	AA0039IJ	1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%	1g	$396	2026-05-28	Buy
aablocks	AA0039IJ	1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one 98%	5g	$1342	2026-05-28	Buy
ACHEMBLOCK	Q65680	1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%	5G	$895	2026-05-25	Buy
ACHEMBLOCK	Q65680	1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%	5G	$895	2026-05-27	Buy
ACHEMBLOCK	Q65680	1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%	1G	$330	2026-05-25	Buy
ACHEMBLOCK	Q65680	1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%	1G	$330	2026-05-27	Buy
ACHEMBLOCK	Q65680	1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%	100MG	$95	2026-05-25	Buy
ACHEMBLOCK	Q65680	1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%	100MG	$95	2026-05-27	Buy
ACHEMBLOCK	Q65680	1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%	25MG	$40	2026-05-25	Buy
ACHEMBLOCK	Q65680	1-(4-((4-((3,4-dichloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one 98%	25MG	$40	2026-05-27	Buy

Next Last

Properties

Melting point :187 - 190° C
Boiling point :629.7±55.0 °C(Predicted)
Density :1.409±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly, Sonicated)
pka :5.35±0.30(Predicted)
form :Solid
color :White to Pale Beige
InChIKey :LPFWVDIFUFFKJU-UHFFFAOYSA-N
SMILES :C(N1CCC(OC2C(OC)=CC3C(C=2)=C(NC2=CC=C(Cl)C(Cl)=C2F)N=CN=3)CC1)(=O)C=C
CAS DataBase Reference :1092364-38-9

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

Poziotinib (HM781-36B) is an irreversible pan-HER inhibitor with IC50 of 3.2 nM, 5.3 nM and 23.5 nM for HER1, HER2, and HER4, respectively. Phase 2.

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Suppliers and manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Poziotinib (HM781-36B) CAS:1092364-38-9

career henan chemical co

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TargetMol Chemicals Inc.

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TianYuan Pharmaceutical CO.,LTD

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Jurong Coupling Biotechnology Co., Ltd.

Hubei Ipure Biology Co., Ltd

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Shanghai UCHEM Inc.

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Poziotinib (HM781-36B)

Properties

Safety Information

Description

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