VUF 5574
|
- $36 - $1829.1
- Product name: VUF 5574
- CAS: 280570-45-8
- MF: C21H17N5O2
- MW: 371.39
- EINECS:
- MDL Number:MFCD06691423
- Synonyms:VUF 5574;N-(2-METHOXYPHENYL)-N-[2-(3-PYRIDINYL)-4-QUINAZOLINYL]-UREA;N-(2-METHOXYPHENYL)-N'-[2-(3-PYRINDINYL)-4-QUINAZOLINYL]-UREA;1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-quinazolin-4-yl)-urea;Urea, N-(2-methoxyphenyl)-N'-[2-(3-pyridinyl)-4-quinazolinyl]-;3-(2-methoxyphenyl)-1-(2-pyridin-3-ylquinazolin-4-yl)urea
23 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Tocris
- TRC
- Usbiological
Package
- 50
- 5mg
- 25mg
- 1mg
- 10MG
- 10
- 50MG
- 100MG
- 250MG
- 1G
- Manufactureraablocks
- Product numberAA00BDOI
- Product descriptionVUF 5574 99%
- Packaging25mg
- Price$88
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BDOI
- Product descriptionVUF 5574 ≥98%
- Packaging1mg
- Price$36
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227438
- Product descriptionVUF 5574 97.00%
- Packaging250MG
- Price$810
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227438
- Product descriptionVUF 5574 97.00%
- Packaging100MG
- Price$405
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1365CM
- Product description1-(2-Methoxyphenyl)-3-(2-(pyridin-3-yl)quinazolin-4-yl)urea
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001018
- Product descriptionVUF 5574 95.00%
- Packaging50MG
- Price$1138.78
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001018
- Product descriptionVUF 5574 95.00%
- Packaging1G
- Price$1829.1
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001018
- Product descriptionVUF 5574 95.00%
- Packaging10MG
- Price$685.21
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6703
- Product descriptionVUF 5574
- Packaging50mg
- Price$1032
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6703
- Product descriptionVUF 5574
- Packaging5mg
- Price$160
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6703
- Product descriptionVUF 5574
- Packaging1mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB6703
- Product descriptionVUF 5574
- Packaging10mg
- Price$210
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number27676
- Product descriptionVUF 5574 ≥98%
- Packaging1mg
- Price$36
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number27676
- Product descriptionVUF 5574 ≥98%
- Packaging5mg
- Price$128
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number27676
- Product descriptionVUF 5574 ≥98%
- Packaging10mg
- Price$169
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0025280
- Product descriptionVUF-5574 99.0%
- Packaging10mg
- Price$200
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BDOI | VUF 5574 99% | 25mg | $88 | 2026-05-28 | Buy |
| aablocks | AA00BDOI | VUF 5574 ≥98% | 1mg | $36 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227438 | VUF 5574 97.00% | 250MG | $810 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227438 | VUF 5574 97.00% | 100MG | $405 | 2026-05-27 | Buy |
| AK Scientific | 1365CM | 1-(2-Methoxyphenyl)-3-(2-(pyridin-3-yl)quinazolin-4-yl)urea | 1mg | $133 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001018 | VUF 5574 95.00% | 50MG | $1138.78 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001018 | VUF 5574 95.00% | 1G | $1829.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0001018 | VUF 5574 95.00% | 10MG | $685.21 | 2021-12-16 | Buy |
| ApexBio Technology | B6703 | VUF 5574 | 50mg | $1032 | 2026-05-06 | Buy |
| ApexBio Technology | B6703 | VUF 5574 | 5mg | $160 | 2026-05-06 | Buy |
| ApexBio Technology | B6703 | VUF 5574 | 1mg | $50 | 2026-05-06 | Buy |
| ApexBio Technology | B6703 | VUF 5574 | 10mg | $210 | 2026-05-06 | Buy |
| Cayman Chemical | 27676 | VUF 5574 ≥98% | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 27676 | VUF 5574 ≥98% | 5mg | $128 | 2026-04-30 | Buy |
| Cayman Chemical | 27676 | VUF 5574 ≥98% | 10mg | $169 | 2026-04-30 | Buy |
| ChemScene | CS-0025280 | VUF-5574 99.0% | 10mg | $200 | 2026-06-04 | Buy |
Properties
Melting point :257-258 °C
Boiling point :444.8±45.0 °C(Predicted)
Density :1.360±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: 1.5 mg/mL, soluble
form :solid
pka :-2.06±0.43(Predicted)
color :white
InChI :1S/C21H17N5O2/c1-28-18-11-5-4-10-17(18)24-21(27)26-20-15-8-2-3-9-16(15)23-19(25-20)14-7-6-12-22-13-14/h2-13H,1H3,(H2,23,24,25,26,27)
InChIKey :YRAFEJSZTVWUMD-UHFFFAOYSA-N
SMILES :COc1ccccc1NC(=O)Nc2nc(nc3ccccc23)-c4cccnc4
Boiling point :444.8±45.0 °C(Predicted)
Density :1.360±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: 1.5 mg/mL, soluble
form :solid
pka :-2.06±0.43(Predicted)
color :white
InChI :1S/C21H17N5O2/c1-28-18-11-5-4-10-17(18)24-21(27)26-20-15-8-2-3-9-16(15)23-19(25-20)14-7-6-12-22-13-14/h2-13H,1H3,(H2,23,24,25,26,27)
InChIKey :YRAFEJSZTVWUMD-UHFFFAOYSA-N
SMILES :COc1ccccc1NC(=O)Nc2nc(nc3ccccc23)-c4cccnc4
Safety Information
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Description
VUF 5574 is an antagonist of the adenosine A3 receptor (Ki = 4.03 nM for the recombinant human receptor). It is greater than 2,500-fold selective for adenosine A3 over A1 and A2A receptors. VUF 5574 (100 nM) decreases phosphorylation of ERK1/2 induced by adenosine in isolated porcine coronary artery smooth muscle cells. It increases oxygen-glucose deprivation-induced reductions in the amplitude of field excitatory postsynaptic potentials (EPSPs) in a rat hippocampal slice model of ischemia when used at a concentration of 100 nM. VUF 5574 (2 μg, intracisternal) reduces sodium nitroprusside-induced heart rate increases in rats.More related product prices
Conivaptan impurity 2,3-Dihydroxybenzoic acid 2,5-Dihydroxybenzoic acid Conivaptan hydrochlorideRelated product price
-
VUF 5574
$36-1829.1 -
2-PYRIDIN-3-YL-QUINAZOLIN-4-YLAMINE
$83-8100 -
Conivaptan impurity
$214-753
Suppliers and manufacturers
Shaanxi Dideu New Materials Co. Ltd
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
HANGZHOU LEAP CHEM CO., LTD.
Aladdin Scientific
3B Pharmachem (Wuhan) International Co.,Ltd.
Nanjing Chemlin Chemical Co., Ltd
Guangzhou Isun Pharmaceutical Co., Ltd
EMMX Biotechnology LLC
Shanghai YuanYe Biotechnology Co., Ltd.
VUF 5574
CAS:280570-45-8