Valspodar
|
- $29 - $4305
- Product name: Valspodar
- CAS: 121584-18-7
- MF: C63H111N11O12
- MW: 1214.62
- EINECS:1312995-182-4
- MDL Number:MFCD00907207
- Synonyms:Valspodar;3'-Keto-bmt(1)-Val(2)-cyclosporin a;Cyclosporin A, 6-((R-(E))-6,7-didehydro-N,4-dimethyl-3-oxo-L-2-aminooctanoic acid)-7-L-valine-;Sdz psc 833;Sdz-psc-833;Cyclo[[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoyl]-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl];6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoicacid]-7-L-valine-cyclosporinA;Valspodar(PSC-833,AMdray)
65 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500μg
- 2mg
- 5 mg
- 10 mg
- 1
- 100mg
- 250mg
- 10mM*1mLinDMSO(Solution)
- 500ug
- 1mg
- 5mg
- 10mg
- 25MG
- 50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA00158V
- Product descriptionValspodar ≥95%
- Packaging1mg
- Price$74
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00158V
- Product descriptionValspodar ≥95%
- Packaging5mg
- Price$213
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00158V
- Product descriptionValspodar ≥95%
- Packaging10mg
- Price$385
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203303
- Product descriptionPSC-833 98.00%
- Packaging5MG
- Price$765
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203303
- Product descriptionPSC-833 98.00%
- Packaging5MG
- Price$765
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203303
- Product descriptionPSC-833 98.00%
- Packaging25MG
- Price$2295
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203303
- Product descriptionPSC-833 98.00%
- Packaging25MG
- Price$2295
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203303
- Product descriptionPSC-833 98.00%
- Packaging1MG
- Price$295
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX203303
- Product descriptionPSC-833 98.00%
- Packaging1MG
- Price$295
- Updated2026-05-25
- Buy
- ManufacturerAK Scientific
- Product numberX5944
- Product descriptionValspodar
- Packaging5mg
- Price$320
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3905
- Product descriptionValspodar
- Packaging10mg
- Price$239
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3905
- Product descriptionValspodar
- Packaging5mg
- Price$258
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3905
- Product descriptionValspodar
- Packaging10mg
- Price$472
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3905
- Product descriptionValspodar
- Packaging1mg
- Price$77
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3905
- Product descriptionValspodar
- Packaging500ug
- Price$42
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA3905
- Product descriptionValspodar
- Packaging5mg
- Price$133
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00158V | Valspodar ≥95% | 1mg | $74 | 2026-05-28 | Buy |
| aablocks | AA00158V | Valspodar ≥95% | 5mg | $213 | 2026-05-28 | Buy |
| aablocks | AA00158V | Valspodar ≥95% | 10mg | $385 | 2026-05-28 | Buy |
| ACHEMBLOCK | X203303 | PSC-833 98.00% | 5MG | $765 | 2026-05-25 | Buy |
| ACHEMBLOCK | X203303 | PSC-833 98.00% | 5MG | $765 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203303 | PSC-833 98.00% | 25MG | $2295 | 2026-05-25 | Buy |
| ACHEMBLOCK | X203303 | PSC-833 98.00% | 25MG | $2295 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203303 | PSC-833 98.00% | 1MG | $295 | 2026-05-27 | Buy |
| ACHEMBLOCK | X203303 | PSC-833 98.00% | 1MG | $295 | 2026-05-25 | Buy |
| AK Scientific | X5944 | Valspodar | 5mg | $320 | 2021-12-16 | Buy |
| ApexBio Technology | A3905 | Valspodar | 10mg | $239 | 2021-12-16 | Buy |
| ApexBio Technology | A3905 | Valspodar | 5mg | $258 | 2026-05-06 | Buy |
| ApexBio Technology | A3905 | Valspodar | 10mg | $472 | 2026-05-06 | Buy |
| ApexBio Technology | A3905 | Valspodar | 1mg | $77 | 2026-05-06 | Buy |
| ApexBio Technology | A3905 | Valspodar | 500ug | $42 | 2026-05-06 | Buy |
| ApexBio Technology | A3905 | Valspodar | 5mg | $133 | 2021-12-16 | Buy |
Properties
Melting point :143-145°C
alpha :D20 -255.1° (c = 0.5 in CHCl3)
Boiling point :1290.1±65.0 °C(Predicted)
Density :1.015±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :12.45±0.70(Predicted)
form :powder
color :white to beige
InChIKey :YJDYDFNKCBANTM-QCWCSKBGSA-N
alpha :D20 -255.1° (c = 0.5 in CHCl3)
Boiling point :1290.1±65.0 °C(Predicted)
Density :1.015±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
pka :12.45±0.70(Predicted)
form :powder
color :white to beige
InChIKey :YJDYDFNKCBANTM-QCWCSKBGSA-N
Safety Information
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Description
PSC 833 is a non-immunosuppressant derivative of cyclosporine and potent multidrug-resistance (MDR) modulator. It restores sensitivity of MDR-P388 murine leukemia cells to cytostatic agents when used at concentrations of 70, 33, 45, 34, and 26 nM in combination with colchicine, vincristine , daunorubicin , doxorubicin , and etoposide , respectively. PSC 833 inhibits basal-to-apical transport and increases apical-to-basal transport of [14C]docetaxel in LLC-GA5-COLO150 cells that overexpress human P-glycoprotein (P-gp). In vivo, PSC 833 increases survival time in MDR-P388 tumor-bearing mice and in an MDR-L1210 leukemia mouse xenograft model when administered in combination with doxorubicin. PSC 833 also prolongs the anti-hyperalgesic effects of intraperitoneally administered pregabalin in a mouse model of cold stress-induced central pain.More related product prices
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