YM 26734
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- $36 - $2821
- Product name: YM 26734
- CAS: 144337-18-8
- MF: C45H62O8
- MW: 730.97
- EINECS:
- MDL Number:MFCD00918068
- Synonyms:YM 26734;1-Dodecanone, 1,1'-(5-(3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxy-1,3-phenylene)bis-;4-(3,5-Didodecanoyl-2,4,6-trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman;1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-1-dodecanone;1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one;1-{3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]phenyl}dodecan-1-one
37 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA001JAC
- Product descriptionYM-26734 ≥95%(mixtureofdiastereomers)
- Packaging1mg
- Price$40
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001JAC
- Product descriptionYM-26734 ≥95%(mixtureofdiastereomers)
- Packaging5mg
- Price$143
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001JAC
- Product descriptionYM-26734 ≥95%(mixtureofdiastereomers)
- Packaging10mg
- Price$263
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127660
- Product description1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis[1-dodecanone] 98%
- Packaging5MG
- Price$360
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127660
- Product description1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis[1-dodecanone] 98%
- Packaging25MG
- Price$1080
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberAMTA047
- Product descriptionYM-26734 97%
- Packaging50mg
- Price$792
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberAMTA047
- Product descriptionYM-26734 97%
- Packaging25mg
- Price$403
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberSYN5086
- Product descriptionYM-26734
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberAMTA047
- Product descriptionYM-26734 97%
- Packaging5mg
- Price$101
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberAMTA047
- Product descriptionYM-26734 97%
- Packaging10mg
- Price$200
- Updated2026-06-04
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001214
- Product descriptionYM 26734 95.00%
- Packaging10MG
- Price$265.65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7091
- Product descriptionYM 26734
- Packaging10mg
- Price$430
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberUFA33718
- Product descriptionYM 26734
- Packaging25mg
- Price$1267.5
- Updated2026-06-05
- Buy
- ManufacturerBiosynth
- Product numberUFA33718
- Product descriptionYM 26734
- Packaging50mg
- Price$1763.5
- Updated2026-06-05
- Buy
- ManufacturerBiosynth
- Product numberUFA33718
- Product descriptionYM 26734
- Packaging100mg
- Price$2821
- Updated2026-06-05
- Buy
- ManufacturerCayman Chemical
- Product number17631
- Product descriptionYM-26734 ≥95%
- Packaging25mg
- Price$553
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001JAC | YM-26734 ≥95%(mixtureofdiastereomers) | 1mg | $40 | 2026-05-28 | Buy |
| aablocks | AA001JAC | YM-26734 ≥95%(mixtureofdiastereomers) | 5mg | $143 | 2026-05-28 | Buy |
| aablocks | AA001JAC | YM-26734 ≥95%(mixtureofdiastereomers) | 10mg | $263 | 2026-05-28 | Buy |
| ACHEMBLOCK | U127660 | 1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis[1-dodecanone] 98% | 5MG | $360 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127660 | 1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis[1-dodecanone] 98% | 25MG | $1080 | 2026-05-27 | Buy |
| AK Scientific | AMTA047 | YM-26734 97% | 50mg | $792 | 2026-06-04 | Buy |
| AK Scientific | AMTA047 | YM-26734 97% | 25mg | $403 | 2026-06-04 | Buy |
| AK Scientific | SYN5086 | YM-26734 | 10mg | $150 | 2021-12-16 | Buy |
| AK Scientific | AMTA047 | YM-26734 97% | 5mg | $101 | 2026-06-04 | Buy |
| AK Scientific | AMTA047 | YM-26734 97% | 10mg | $200 | 2026-06-04 | Buy |
| American Custom Chemicals Corporation | INB0001214 | YM 26734 95.00% | 10MG | $265.65 | 2021-12-16 | Buy |
| ApexBio Technology | B7091 | YM 26734 | 10mg | $430 | 2026-05-06 | Buy |
| Biosynth | UFA33718 | YM 26734 | 25mg | $1267.5 | 2026-06-05 | Buy |
| Biosynth | UFA33718 | YM 26734 | 50mg | $1763.5 | 2026-06-05 | Buy |
| Biosynth | UFA33718 | YM 26734 | 100mg | $2821 | 2026-06-05 | Buy |
| Cayman Chemical | 17631 | YM-26734 ≥95% | 25mg | $553 | 2024-03-01 | Buy |
Properties
storage temp. :Store at -20°C
solubility :Soluble to 100 mM in DMSO and to 100 mM in ethanol
form :Powder
color :white to beige
InChIKey :CEJAYJCUSZHYDS-UHFFFAOYSA-N
SMILES :OC1=C(C2CC(C3=CC=C(O)C=C3)OC4=C2C=CC(O)=C4)C(O)=C(C(CCCCCCCCCCC)=O)C(O)=C1C(CCCCCCCCCCC)=O
solubility :Soluble to 100 mM in DMSO and to 100 mM in ethanol
form :Powder
color :white to beige
InChIKey :CEJAYJCUSZHYDS-UHFFFAOYSA-N
SMILES :OC1=C(C2CC(C3=CC=C(O)C=C3)OC4=C2C=CC(O)=C4)C(O)=C(C(CCCCCCCCCCC)=O)C(O)=C1C(CCCCCCCCCCC)=O
Safety Information
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Description
Secreted phospholipases A2 (sPLA2s) are a diverse family of low molecular weight PLA2s with tissue-specific expression patterns and actions. The group IIA sPLA2 (sPLA2-IIA) was originally purified from platelets and exudates from patients with rheumatoid arthritis. Its expression can be induced by inflammatory mediators, and mouse studies suggest that it may play roles in colorectal polyposis, atherosclerosis, and bacterial infections. YM-26734 is a derivative of a compound isolated from the fruit of H. amygdaline that competitively inhibits rabbit platelet sPLA2 with an IC50 value of 85 nM. It inhibits sPLA2-hGIIA, -mGIIA, -rGIIA, -hGV, -mGV, -hGX, and -mGX with IC50 values of 80, 30, 120, 110, 520, >1600, and >1600 nM, respectively. YM-26734 displays minimal activity at cytosolic PLA2, COX and lipoxygenase. At 45 μg/ear or 11 mg/kg i.v., YM-26734 has been used to ameliorate local inflammatory responses in TPA-induced mouse ear edema.More related product prices
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