cis-4-Hydroxy-L-proline
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- $4 - $3787
- Product name: cis-4-Hydroxy-L-proline
- CAS: 618-27-9
- MF: C5H9NO3
- MW: 131.13
- EINECS:210-542-1
- MDL Number:MFCD00064319
- Synonyms:(S)-Allo-hydroxyproline;cis-4-Hydroxy-L-proline collagen synthesis inhibitor;L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLIC ACID;L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLLIC ACID;L-ALLO-HYDROXYPROLINE;CIS-4-HYDROXY-L-PROLINE;CIS-L-4-HYDROXYPROLINE;CHYP
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Brand
- aablocks
- ACHEMBLOCK
- Activate Scientific
- AHH
- AK Scientific
- Alichem
- Ambeed
- American Custom Chemicals Corporation
- Apolloscientific
- AstaTech
- Chemenu
- Chem-Impex
- ChemPep
- ChemScene
- Crysdot
- Iris Biotech GmbH
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 10mg
- 50MG
- 100MG
- 100.00mg
- 250mg
- 500.00mg
- 1g
- 2g
- 2.50g
- 5g
- 10g
- 25g
- 100g
- 500G
- 1000g
- Manufactureraablocks
- Product numberAA0036ZL
- Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98%
- Packaging250mg
- Price$4
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036ZL
- Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 97%
- Packaging1g
- Price$6
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036ZL
- Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98%
- Packaging5g
- Price$13
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036ZL
- Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98%
- Packaging25g
- Price$42
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036ZL
- Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98%
- Packaging10g
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0036ZL
- Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98%
- Packaging100g
- Price$156
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO30697
- Product description(2S,4S)-4-hydroxypyrrolidine-2-carboxylicacid 95%
- Packaging5G
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberO30697
- Product description(2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid 95%
- Packaging100G
- Price$230
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO30697
- Product description(2S,4S)-4-hydroxypyrrolidine-2-carboxylicacid 95%
- Packaging25G
- Price$285
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS3728-A
- Product descriptionCis-4-Hydroxy-L-proline 98+%
- Packaging1g
- Price$42
- Updated2021-12-16
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- ManufacturerAHH
- Product numberMT-15523
- Product descriptioncis-4-Hydroxy-L-proline 98%
- Packaging10g
- Price$635
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-15523
- Product descriptioncis-4-Hydroxy-L-proline 97%
- Packaging10g
- Price$635
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-15523
- Product descriptioncis-4-Hydroxy-L-proline 97%
- Packaging10g
- Price$635
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberJ93503
- Product descriptioncis-4-Hydroxy-L-proline
- Packaging100g
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ93503
- Product descriptioncis-4-Hydroxy-L-proline
- Packaging1g
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number618279
- Product description(2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid
- Packaging25g
- Price$551.2
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0036ZL | (2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98% | 250mg | $4 | 2026-05-28 | Buy |
| aablocks | AA0036ZL | (2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 97% | 1g | $6 | 2026-05-28 | Buy |
| aablocks | AA0036ZL | (2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98% | 5g | $13 | 2026-05-28 | Buy |
| aablocks | AA0036ZL | (2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98% | 25g | $42 | 2026-05-28 | Buy |
| aablocks | AA0036ZL | (2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98% | 10g | $19 | 2026-05-28 | Buy |
| aablocks | AA0036ZL | (2S,4S)-4-Hydroxypyrrolidine-2-carboxylic acid 98% | 100g | $156 | 2026-05-28 | Buy |
| ACHEMBLOCK | O30697 | (2S,4S)-4-hydroxypyrrolidine-2-carboxylicacid 95% | 5G | $95 | 2021-12-16 | Buy |
| ACHEMBLOCK | O30697 | (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid 95% | 100G | $230 | 2026-05-27 | Buy |
| ACHEMBLOCK | O30697 | (2S,4S)-4-hydroxypyrrolidine-2-carboxylicacid 95% | 25G | $285 | 2021-12-16 | Buy |
| Activate Scientific | AS3728-A | Cis-4-Hydroxy-L-proline 98+% | 1g | $42 | 2021-12-16 | Buy |
| AHH | MT-15523 | cis-4-Hydroxy-L-proline 98% | 10g | $635 | 2021-12-16 | Buy |
| AHH | MT-15523 | cis-4-Hydroxy-L-proline 97% | 10g | $635 | 2026-05-25 | Buy |
| AHH | MT-15523 | cis-4-Hydroxy-L-proline 97% | 10g | $635 | 2026-05-26 | Buy |
| AK Scientific | J93503 | cis-4-Hydroxy-L-proline | 100g | $650 | 2021-12-16 | Buy |
| AK Scientific | J93503 | cis-4-Hydroxy-L-proline | 1g | $25 | 2021-12-16 | Buy |
| Alichem | 618279 | (2S,4S)-4-Hydroxypyrrolidine-2-carboxylicacid | 25g | $551.2 | 2021-12-16 | Buy |
Properties
Melting point :257 °C (dec.) (lit.)
alpha :-59 º (c=2, H2O)
Boiling point :242.42°C (rough estimate)
Density :1.3121 (rough estimate)
refractive index :-59 ° (C=2, H2O)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :soluble
form :Powder
pka :2.14±0.40(Predicted)
color :White to beige
Water Solubility :soluble
Merck :14,4840
BRN :81440
Major Application :peptide synthesis
InChI :1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
InChIKey :PMMYEEVYMWASQN-IMJSIDKUSA-N
SMILES :O[C@@H]1CN[C@@H](C1)C(O)=O
CAS DataBase Reference :618-27-9(CAS DataBase Reference)
EPA Substance Registry System :L-Proline, 4-hydroxy-, (4S)- (618-27-9)
alpha :-59 º (c=2, H2O)
Boiling point :242.42°C (rough estimate)
Density :1.3121 (rough estimate)
refractive index :-59 ° (C=2, H2O)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :soluble
form :Powder
pka :2.14±0.40(Predicted)
color :White to beige
Water Solubility :soluble
Merck :14,4840
BRN :81440
Major Application :peptide synthesis
InChI :1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
InChIKey :PMMYEEVYMWASQN-IMJSIDKUSA-N
SMILES :O[C@@H]1CN[C@@H](C1)C(O)=O
CAS DataBase Reference :618-27-9(CAS DataBase Reference)
EPA Substance Registry System :L-Proline, 4-hydroxy-, (4S)- (618-27-9)
Safety Information
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Description
cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.More related product prices
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