AURANTIO-OBTUSIN
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- CAS-Nr.
- 67979-25-3
- Englisch Name:
- AURANTIO-OBTUSIN
- Synonyma:
- URANTIO-OBTUSIN;AURANTIO-OBTUSIN;Aurantio-obtusifolin;67979-25-3 AURANTIO-OBTUSIN;Aurantio-obtusin (Standard);Aurantio-obtusin, 10 mM in DMSO;Aurantioobtusin, 98%, from Catsia tora Linn;1,3,7-Trihydroxy-2,8-dimethoxy-6-methylanthracene-9,10-dione;1,3,7-Trihydroxy-2,8-diMethoxy-6-Methyl-9,10-anthracenedione;9,10-Anthracenedione, 1,3,7-trihydroxy-2,8-dimethoxy-6-methyl-
- CBNumber:
- CB61414271
- Summenformel:
- C17H14O7
- Molgewicht:
- 330.29
- MOL-Datei:
- 67979-25-3.mol
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AURANTIO-OBTUSIN Eigenschaften
- Schmelzpunkt:
- 265-266 °C
- Siedepunkt:
- 594.6±50.0 °C(Predicted)
- Dichte
- 1.510±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- Soluble in chloroform, DMSO and methan
- Aggregatzustand
- powder
- pka
- 6.32±0.20(Predicted)
- Farbe
- Orange
- Major Application
- food and beverages
- InChI
- InChI=1S/C17H14O7/c1-6-4-7-11(17(24-3)12(6)19)14(21)10-8(13(7)20)5-9(18)16(23-2)15(10)22/h4-5,18-19,22H,1-3H3
- InChIKey
- RNXZPKOEJUFJON-UHFFFAOYSA-N
- SMILES
- C1(O)=C2C(C(=O)C3=C(C2=O)C(OC)=C(O)C(C)=C3)=CC(O)=C1OC
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| WGK Germany |
WGK 3 |
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| HS Code |
29389090 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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AURANTIO-OBTUSIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Aurantioobtusin is an anthraquinone originally isolated from
Cassia seeds with diverse biological activities. It inhibits rat lens aldose reductase (RLAR)
in vitro (IC
50 = 13.6 μM). Aurantioobtusin (10 and 100 μM) activates the aryl hydrocarbon receptor (AhR) in a concentration-dependent manner. It inhibits rat platelet aggregation induced by arachidonic acid (Item Nos.
90010 |
90010.1 |
10006607), ADP, and collagen. Aurantioobtusin induces vasorelaxation in isolated precontracted rat mesenteric artery rings, an effect that is inhibited by the PI3K inhibitor LY290042 or inhibition of endothelial nitric oxide synthase (eNOS). It is larvicidal against
A. gambiae mosquitoes (LD
50 = 10 ppm).
Verwenden
A compound found in herbal remedies, believed to have an effect on blood platelet aggregation and lower blood lipid count
Definition
ChEBI: A trihydroxyanthraquinone that is 1,3,7-trihydroxy-9,10-anthraquinone which is by methoxy groups at positions 2 and 8, and by a methyl group at position 6.
AURANTIO-OBTUSIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
AURANTIO-OBTUSIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 250)Lieferanten
67979-25-3()Verwandte Suche:
- 1,3,7-Trihydroxy-2,8-diMethoxy-6-Methyl-9,10-anthracenedione
- Aurantio-obtusifolin
- AURANTIO-OBTUSIN
- 1,3,7-Trihydroxy-2,8-dimethoxy-6-methylanthracene-9,10-dione
- URANTIO-OBTUSIN
- Aurantioobtusin, 98%, from Catsia tora Linn
- 9,10-Anthracenedione, 1,3,7-trihydroxy-2,8-dimethoxy-6-methyl-
- 67979-25-3 AURANTIO-OBTUSIN
- Aurantio-obtusin, 10 mM in DMSO
- Aurantio-obtusin (Standard)
- 67979-25-3
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Intermediates & Fine Chemicals
- Pharmaceuticals
- chemical reagent
