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Nucleoside drugs

Many of the purine pyrimidine nucleoside analogues, which are promising antiviral compounds, are antiviral in tissue culture and in vivo. The compounds with selective inhibition of the virus, low toxicity, and effective in animals develop into nuclei Glycosides antiviral drugs. Currently, nucleoside drugs that are effective in clinical applications, have commodities, and have been recognized include iodine glycosides, trifluorothymidine, cyclosine, a sugar adenosine, acyclovir and so on. Nucleoside drugs that have a certain effect in clinical trials, have goods in some countries, yet to be recognized include ribavirin, arabinosyl adenosine monophosphate, bromide uridine and so on. Clinical trials are under way to observe the effect include fluoro-iodine cytosine. The new anti-viral nucleoside compounds have been reported is still in research and development. Nucleoside analogs are nucleic acid antimetabolites that are structurally analogous to nucleic acid precursors, competing for nucleic acid synthase enzyme systems, replacing normal nucleic acid precursors, or inhibiting nucleic acid synthetases, blocking viral or cellular nucleic acid synthesis, selectively inhibiting viral nucleic acids , while have little effect on the synthesis of nucleic acid.
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Structure Chemical Name CAS MF
Inosine-5'-monophosphate Disodium Salt octahydrate Inosine-5'-monophosphate Disodium Salt octahydrate 20813-76-7 C10H16N4NaO9P
5μ-Inosinic acid hydrate disodium salt, I-5μ-P, IMP, Inosinic Acid 5μ-Inosinic acid hydrate disodium salt, I-5μ-P, IMP, Inosinic Acid 352195-40-5 C10H16N4NaO9P
N4-Acetyl-2'-Fluoro-2'-deoxycytidine N4-Acetyl-2'-Fluoro-2'-deoxycytidine 159414-97-8 C11H14FN3O5
7-DEAZA-2'-DEOXYGUANOSINE 7-DEAZA-2'-DEOXYGUANOSINE 86392-75-8 C11H14N4O4
2'-Deoxyuridine-5'-triphosphate trisodium salt 2'-Deoxyuridine-5'-triphosphate trisodium salt 102814-08-4 C9H16N2NaO14P3
7-DEAZA-2'-DEOXYADENOSINE 7-DEAZA-2'-DEOXYADENOSINE 60129-59-1 C11H14N4O3
N6,N6-DIMETHYLADENOSINE N6,N6-DIMETHYLADENOSINE 2620-62-4 C12H17N5O4
2-THIOCYTIDINE 2-THIOCYTIDINE 13239-97-9 C9H13N3O4S
7-DEAZA-7-IODO-2'-DEOXYGUANOSINE 7-DEAZA-7-IODO-2'-DEOXYGUANOSINE 172163-62-1 C11H13IN4O4
Uridine 5'-monophosphate Uridine 5'-monophosphate 58-97-9 C9H13N2O9P
UDP SODIUM SALT UDP SODIUM SALT 19817-91-5 C9H15N2NaO12P2
5'-O-TRITYLURIDINE 5'-O-TRITYLURIDINE 6554-10-5 C28H26N2O6
6-AMINO-2-HYDROXYPURINE 6-AMINO-2-HYDROXYPURINE 49722-90-9 C10H12N10O6S
7,9-DIMETHYLGUANINE 7,9-DIMETHYLGUANINE 524-35-6 C7H9N5O
N4-AMINOCYTIDINE N4-AMINOCYTIDINE 57294-74-3 C9H14N4O5
2,3,5-Tri-O-benzoyl-beta-D-ribofuranosyl cyanide 2,3,5-Tri-O-benzoyl-beta-D-ribofuranosyl cyanide 23316-67-8 C27H21NO7
TUBERCIDIN TUBERCIDIN 69-33-0 C11H14N4O4
5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine 5'-O-(Dimethoxytrityl)-5-iodo-2'-deoxyuridine 104375-88-4 C30H29IN2O7
URACIL-5-CARBOXYLIC ACID MONOHYDRATE URACIL-5-CARBOXYLIC ACID MONOHYDRATE 69727-34-0 C5H6N2O5
2'-DEOXYGUANOSINE 3'-MONOPHOSPHATE SODIUM SALT 2'-DEOXYGUANOSINE 3'-MONOPHOSPHATE SODIUM SALT 102814-03-9 C10H13N5NaO7P
3'-AZIDO-2',3'-DIDEOXYURIDINE 3'-AZIDO-2',3'-DIDEOXYURIDINE 84472-85-5 C9H11N5O4
2-Chloroadenosine hemidydrate 2-Chloroadenosine hemidydrate 81012-94-4 C10H14ClN5O5
DMT-dC(ac) Phosphoramidite DMT-dC(ac) Phosphoramidite 154110-40-4 C41H50N5O8P
2'-(O-METHYL)-5-METHYLCYTIDINE 2'-(O-METHYL)-5-METHYLCYTIDINE 113886-70-7 C11H17N3O5
8-BROMO-2'-DEOXYADENOSINE 8-BROMO-2'-DEOXYADENOSINE 14985-44-5 C10H12BrN5O3
6-THIOGUANOSINE 6-THIOGUANOSINE 85-31-4 C10H13N5O4S
Adenosine-5'-diphosphate trilithium salt Adenosine-5'-diphosphate trilithium salt 31008-64-7 C10H16LiN5O10P2
DMT-dG(dmf) Phosphoramidite DMT-dG(dmf) Phosphoramidite 330628-04-1 C43H53N8O7P
Bucladesine Bucladesine 362-74-3 C18H24N5O8P
N6-BENZYLADENOSINE N6-BENZYLADENOSINE 4294-16-0 C17H19N5O4
6-CYANOPURINE 6-CYANOPURINE 2036-13-7 C6H3N5
5'-DMT-RIBO ADENOSINE (N-BZ) 5'-DMT-RIBO ADENOSINE (N-BZ) 81246-82-4 C38H35N5O7
ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT ADENOSINE-2':3'-CYCLIC MONOPHOSPHATE, SODIUM SALT 37063-35-7 C10H13N5NaO6P
5'-CHLORO-5'-DEOXYADENOSINE 5'-CHLORO-5'-DEOXYADENOSINE 892-48-8 C10H12ClN5O3
3'-Azido-2',3'-dideoxyadenosine 3'-Azido-2',3'-dideoxyadenosine 66323-44-2 C10H12N8O2
8-BROMOGUANINE 8-BROMOGUANINE 3066-84-0 C5H4BrN5O
8-Chloroadenosine 8-Chloroadenosine 34408-14-5 C10H12ClN5O4
2'-(O-METHYL)-INOSINE 2'-(O-METHYL)-INOSINE 3881-21-8 C11H14N4O5
951-77-9 951-77-9 951-77-9 C9H13N3O4
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT 40732-48-7 C10H13N5NaO7P
8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT 76939-46-3 C10H12BrN5NaO6P
9-ETHYLGUANINE 9-ETHYLGUANINE 879-08-3 C7H9N5O
2-(DIMETHYLAMINO)GUANOSINE 2-(DIMETHYLAMINO)GUANOSINE 2140-67-2 C12H17N5O5
2'-Amino-2'-deoxyadenosine 2'-Amino-2'-deoxyadenosine 10414-81-0 C10H14N6O3
ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE ADENOSINE 2' -& 3'-MONOPHOSPHATE FREE 130-49-4 C10H14N5O7P
2',3',5'-Triacetylinosine 2',3',5'-Triacetylinosine 38972-84-8 C16H18N4O5
2'-C-Methylcytidine 2'-C-Methylcytidine 20724-73-6 C10H15N3O5
Deoxyribonucleic acid sodium salt Deoxyribonucleic acid sodium salt 68938-01-2 C17H15BrFNO3
N2-Phenylacetyl guanosine N2-Phenylacetyl guanosine 132628-16-1 C18H19N5O6
dmf-dG-CE-Phophoramidite dmf-dG-CE-Phophoramidite
DMT-dA(bz) Phosphoramidite DMT-dA(bz) Phosphoramidite 98796-53-3 C47H52N7O7P
2'-C-Methyluridine 2'-C-Methyluridine 31448-54-1 C10H14N2O6
6-MERCAPTOPURINE RIBOSIDE 6-MERCAPTOPURINE RIBOSIDE 574-25-4 C10H12N4O4S
7-METHYLGUANINE 7-METHYLGUANINE 578-76-7 C6H7N5O
2(1H)-Pyrimidinone, 4-(methylamino)- (9CI) 2(1H)-Pyrimidinone, 4-(methylamino)- (9CI) 6220-47-9 C5H7N3O
8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE 23583-48-4 C10H11BrN5O6P
5-CHLORO-2'-DEOXYURIDINE 5-CHLORO-2'-DEOXYURIDINE 50-90-8 C9H11ClN2O5
2'-Fluoro-2,6-diaminopurine-2'-deoxyriboside 2'-Fluoro-2,6-diaminopurine-2'-deoxyriboside
8-AMINOGUANOSINE 8-AMINOGUANOSINE 3868-32-4 C10H14N6O5
N2-PHENOXYACETYL-2'-DEOXYGUANOSINE N2-PHENOXYACETYL-2'-DEOXYGUANOSINE 115389-03-2 C18H19N5O6
N2-Benzoyl-D-guanosine N2-Benzoyl-D-guanosine 3676-72-0 C17H17N5O6
5-IODO-2',3'-DIDEOXYURIDINE 5-IODO-2',3'-DIDEOXYURIDINE 105784-83-6 C9H11IN2O4
3'-DEOXYURIDINE 3'-DEOXYURIDINE 7057-27-4 C9H12N2O5
Xanthine sodium salt Xanthine sodium salt 1196-43-6 C5H5N4NaO2
L-Adenosine L-Adenosine 3080-29-3 C10H13N5O4
8-NITROGUANINE 8-NITROGUANINE 168701-80-2 C5H4N6O3
DI-TERT-BUTYLCHLOROSILANE DI-TERT-BUTYLCHLOROSILANE 56310-18-0 C8H19ClSi
URIC ACID SODIUM SALT URIC ACID SODIUM SALT 1198-77-2 C5H5N4NaO3
1,N6-ETHENOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT 1,N6-ETHENOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT 103213-51-0 C12H11N5NaO6P
Deoxynucleotide Deoxynucleotide
Capecitabine Capecitabine 158798-73-3 C15H22FN3O6
6-CARBOXY-2,4-DIHYDROXYPYRIMIDINE MONOSODIUM SALT 6-CARBOXY-2,4-DIHYDROXYPYRIMIDINE MONOSODIUM SALT 154-85-8 C5H5N2NaO4
2'-C-Methyladenosine 2'-C-Methyladenosine 15397-12-3 C11H15N5O4
5'-Deoxy-5-fluoro-2',3'-O-isopropylidene-D-cytidine 5'-Deoxy-5-fluoro-2',3'-O-isopropylidene-D-cytidine 66335-37-3 C12H16FN3O4
(E)-5-(2-CARBOMETHOXYVINYL)-2'-DEOXYURIDINE (E)-5-(2-CARBOMETHOXYVINYL)-2'-DEOXYURIDINE 86163-17-9 C13H16N2O7
7,8-Dihydro-7-methylguanosine 7,8-Dihydro-7-methylguanosine 15313-37-8 C11H17N5O5
8-CHLOROGUANINE 8-CHLOROGUANINE 22052-03-5 C5H4ClN5O
5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE 3031-94-5 C9H15N4O8P
2'-AMINO-D-CYTIDINE 2'-AMINO-D-CYTIDINE 26889-42-9 C9H14N4O4
2-Amino-2'-deoxy-2'-fluoro-D-adenosine 2-Amino-2'-deoxy-2'-fluoro-D-adenosine 134444-47-6 C10H13FN6O3
ISOCAFFEINE ISOCAFFEINE 519-32-4 C8H10N4O2
SULPHOSUCCINIMIDYL-6-(BIOTINAMIDO)HEXANOATE SULPHOSUCCINIMIDYL-6-(BIOTINAMIDO)HEXANOATE 127062-22-0 C20H31N4NaO9S2
5'-AMINOADENOSINE 5'-AMINOADENOSINE 14365-44-7 C10H14N6O3
2-PHENYLAMINOADENOSINE 2-PHENYLAMINOADENOSINE 53296-10-9 C16H18N6O4
3'-DEOXYGUANOSINE 3'-DEOXYGUANOSINE 3608-58-0 C10H13N5O4
6-METHYLMERCAPTOPURINE RIBOSIDE 6-METHYLMERCAPTOPURINE RIBOSIDE 342-69-8 C11H14N4O4S
6-Thioguanosine hydrate 6-Thioguanosine hydrate 345909-25-3 C10H13N5O4S
L-Cytidine L-Cytidine 26524-60-7 C9H13N3O5
3'-UMP NA 3'-UMP NA 35170-03-7 C9H14N2NaO9P
1-METHYLURIC ACID 1-METHYLURIC ACID 708-79-2 C6H6N4O3
2'-C-Methylguanosine 2'-C-Methylguanosine 374750-30-8 C11H15N5O5
L-Guanosine L-Guanosine 26578-09-6 C10H13N5O5
8-AZAXANTHIN 8-AZAXANTHIN 1468-26-4 C4H3N5O2
6-AZAURACIL 6-AZAURACIL 18802-37-4 C3H5N3O2
2'-O-Methyl-5'-O-DMT-Uridine 2'-O-Methyl-5'-O-DMT-Uridine
8-OXO-2'-DEOXYGUANOSINE 8-OXO-2'-DEOXYGUANOSINE 88847-89-6 C10H13N5O5
3'-Deoxycytidine 3'-Deoxycytidine 7057-33-2 C9H13N3O4
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE 7665-99-8 C10H12N5O7P
7-METHYLGUANOSINE 7-METHYLGUANOSINE 20244-86-4 C11H15N5O5
6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL 6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL 6632-68-4 C6H8N4O3
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