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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
N-DESMETHYLCITALOPRAM HYDROCHLORIDE N-DESMETHYLCITALOPRAM HYDROCHLORIDE 144025-14-9 C19H19FN2O
NAPHTHALENE-13C10 NAPHTHALENE-13C10 219526-41-7 C10H8
DIBENZ[A,I]ACRIDINE DIBENZ[A,I]ACRIDINE 226-92-6 C21H13N
ETHYL FORMATE-D1 ETHYL FORMATE-D1 35976-76-2 C3H6O2
METHYL TRIBROMOACETATE, 99 METHYL TRIBROMOACETATE, 99 3222-05-7 C3H3Br3O2
SODIUM O-IODOHIPPURATE SODIUM O-IODOHIPPURATE 133-17-5 C9H7INNaO3
METFORMIN-D6, HYDROCHLORIDE METFORMIN-D6, HYDROCHLORIDE 1185166-01-1 C4H6ClD6N5
1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea dihydrochloride 1,3-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea dihydrochloride 5318-76-3 C19H22Cl2N6O
1-tert-butylamino-3-(o-cyclopentylphenoxy)propan-2-ol hydrochloride 1-tert-butylamino-3-(o-cyclopentylphenoxy)propan-2-ol hydrochloride 28163-36-2 C18H30ClNO2
2-(4-chloro-3-sulphamoylbenzoyl)benzoic acid 2-(4-chloro-3-sulphamoylbenzoyl)benzoic acid 5270-74-6 C14H10ClNO5S
5H-dibenzo[a,d]cycloheptene 5H-dibenzo[a,d]cycloheptene 256-81-5 C15H12
PENFLUORON PENFLUORON 35367-31-8 C15H9F5N2O2
CIS-MEVINPHOS CIS-MEVINPHOS 338-45-4 C7H13O6P
DESMETHYLDOXEPIN DESMETHYLDOXEPIN 1225-56-5 C18H19NO
CHLORPYRIFOS-METHYL-OXON CHLORPYRIFOS-METHYL-OXON 5598-52-7 C7H7Cl3NO4P
APOLIPOPROTEIN A-I, HUMAN APOLIPOPROTEIN A-I, HUMAN 1426185-50-3
PYRIDATE METABOLITE PYRIDATE METABOLITE 40020-01-7 C10H7ClN2O
7-AMINONITRAZEPAM 7-AMINONITRAZEPAM 4928-02-3 C15H13N3O
ETOBENZANID ETOBENZANID 79540-50-4 C16H15Cl2NO3
TIZANIDINE RELATED COMPOUND C (50 MG) (1-ACETYLIMIDAZOLIDINE-2-THIONE) TIZANIDINE RELATED COMPOUND C (50 MG) (1-ACETYLIMIDAZOLIDINE-2-THIONE) 5391-52-6 C5H8N2OS
HALOPERIDOL METABOLITE II HALOPERIDOL METABOLITE II 34104-67-1 C21H25ClFNO2
CROTONYLBETAINE(CARNITINE IMPURITY)(RG) CROTONYLBETAINE(CARNITINE IMPURITY)(RG) 927-89-9 C16H30N2O6
BISPHENOL F DIGLYCIDYL ETHER BISPHENOL F DIGLYCIDYL ETHER 2095-03-6 C19H20O4
19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE 82209-74-3 C20H30O3
6H-BENZO[CD]PYREN-6-ONE 6H-BENZO[CD]PYREN-6-ONE 3074-00-8 C19H10O
9(Z),11(E)-OCTADECADIENOIC ACID 9(Z),11(E)-OCTADECADIENOIC ACID 2540-56-9 C18H32O2
4-CHLOROBENZYLIDENE PHTHALIDE 4-CHLOROBENZYLIDENE PHTHALIDE 20526-97-0 C15H9ClO2
1,5-dihydro-4H-imidazo[4,5-d]-1,2,3-triazin-4-one 1,5-dihydro-4H-imidazo[4,5-d]-1,2,3-triazin-4-one 4656-86-4 C4H3N5O
3-amino-5-(aminosulphonyl)-4-phenoxybenzoic acid 3-amino-5-(aminosulphonyl)-4-phenoxybenzoic acid 28328-54-3 C13H12N2O5S
2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one 152-93-2 C10H16N4O7
Thiacloprid-Amid, Pestanal Thiacloprid-Amid, Pestanal 676228-91-4 C10H11ClN4OS
Flufenacet OA, Pestanal Flufenacet OA, Pestanal 201668-31-7 C11H12FNO3
Tralopyril Tralopyril 122454-29-9 C12H5BrClF3N2
Flucycloxuron Flucycloxuron 113036-88-7 C25H20ClF2N3O3
BISPHENOL F BIS(2,3-DIHYDROXYPROPYL) ETHER BISPHENOL F BIS(2,3-DIHYDROXYPROPYL) ETHER 72406-26-9 C19H24O6
uttronin A uttronin A 39941-51-0 C50H82O22
Bisphenol TMC Bisphenol TMC 129188-99-4 C21H26O2
2-[2-METHYL-D3-3-(TRIFLUOROMETHYL)PHENYLAMINO]NICOTINIC ACID 2-[2-METHYL-D3-3-(TRIFLUOROMETHYL)PHENYLAMINO]NICOTINIC ACID 1015856-60-6 C14H8D3F3N2O2
SUDAN IV-D6 SUDAN IV-D6 1014689-18-9 C24H20N4O
PN 203-831 PN 203-831 116169-18-7 C19H19N3O5
N-(KETOCAPROYL)-D,L-HOMOSERINE LACTONE N-(KETOCAPROYL)-D,L-HOMOSERINE LACTONE 76924-95-3 C10H15NO4
SILTHIOFAM SILTHIOFAM 175217-20-6 C13H21NOSSi
METAM-SODIUM DIHYDRATE METAM-SODIUM DIHYDRATE 6734-80-1 C2H10NNaO3S2
DIBENZO(A,C)ACRIDINE DIBENZO(A,C)ACRIDINE 215-62-3 C21H13N
ATRATON-DESISOPROPYL ATRATON-DESISOPROPYL 30360-56-6 C6H11N5O
BROMBUTEROL BROMBUTEROL 41937-02-4 C12H18Br2N2O
Pramipexole Impurity 16 Pramipexole Impurity 16 104632-27-1 C10H18ClN3S
(+/-)-11-NOR-9-CARBOXY-DELTA9-THC (+/-)-11-NOR-9-CARBOXY-DELTA9-THC 104874-50-2 C21H28O4
cis-Glimepiride cis-Glimepiride 684286-46-2 C24H34N4O5S
ent-Voriconazole ent-Voriconazole 137234-63-0 C16H14F3N5O
ethyl 5-(forMylaMino)-1H-pyrazole-4-carboxylate ethyl 5-(forMylaMino)-1H-pyrazole-4-carboxylate 31055-19-3 C7H9N3O3
2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl 2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl 932033-57-3 C34H42O2
Orlistat Related Compound D Orlistat Related Compound D 130793-27-0 C29H53NO5
4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE HCL 4-BROMO-2,5-DIMETHOXYPHENETHYLAMINE HCL 56281-37-9 C10H15BrClNO2
(R,S)-N-NITROSOANABASINE (R,S)-N-NITROSOANABASINE 1133-64-8 C10H13N3O
CLADRIBINE  RELATED  COMPOUND A  (20 MG)  (2-METHOXY-2'-DEOXYADENOSINE) CLADRIBINE RELATED COMPOUND A (20 MG) (2-METHOXY-2'-DEOXYADENOSINE) 24757-70-8 C11H15N5O4
COAGULATION FACTOR VIIA, HUMAN COAGULATION FACTOR VIIA, HUMAN 102786-61-8
BROMFENVINPHOS-METHYL BROMFENVINPHOS-METHYL 13104-21-7 C10H10BrCl2O4P
DL-AMPHETAMINE (D5) DL-AMPHETAMINE (D5) 65538-33-2 C9H13N
2,3',4,4',6-PENTABROMODIPHENYL ETHER 2,3',4,4',6-PENTABROMODIPHENYL ETHER 189084-66-0 C12H5Br5O
MECOPROP-2-OCTYL ESTER MECOPROP-2-OCTYL ESTER 28473-03-2 C18H27ClO3
7-METHOXY-2,2-DIMETHYL-3-CHROMENE 7-METHOXY-2,2-DIMETHYL-3-CHROMENE 17598-02-6 C12H14O2
PRIMULAVERIN PRIMULAVERIN 154-61-0 C20H28O13
2,2',4,4',5-PENTABROMODIPHENYL ETHER 2,2',4,4',5-PENTABROMODIPHENYL ETHER 60348-60-9 C12H5Br5O
Citalopram hydrochloride Citalopram hydrochloride 85118-27-0 C20H22ClFN2O
2-ethylhexyl (4-chloro-2-methylphenoxy)acetate 2-ethylhexyl (4-chloro-2-methylphenoxy)acetate 29450-45-1 C17H25ClO3
INTERFERON ALFA-2B INTERFERON ALFA-2B 99210-65-8
ISO-MALATHION ISO-MALATHION 3344-12-5 C10H19O6PS2
Benalaxyl-M Benalaxyl-M 98243-83-5 C20H23NO3
Orysastrobin Orysastrobin 248593-16-0 C18H25N5O5
ATRAZINE-DESISOPROPYL-2-HYDROXY ATRAZINE-DESISOPROPYL-2-HYDROXY 7313-54-4 C5H9N5O
D-gamma-Tocotrienol D-gamma-Tocotrienol 14101-61-2 C28H42O2
1-(3,4-Methylenedioxyphenyl)-2-butanamine 1-(3,4-Methylenedioxyphenyl)-2-butanamine 42542-07-4 C11H15NO2
LY 267108 LY 267108 105882-69-7 C37H65NO12
(+/-)-2-(METHYLAMINO)PROPIOPHENONE HYDROCHLORIDE (+/-)-2-(METHYLAMINO)PROPIOPHENONE HYDROCHLORIDE 49656-78-2 C10H14ClNO
NITRAZEPAM-D5 NITRAZEPAM-D5 136765-45-2 C15H6D5N3O3
ACETATE ACETATE 13867-82-8 C23H31Cl3O4
(Z)-METOMINOSTROBIN (Z)-METOMINOSTROBIN 133408-51-2 C16H16N2O3
CHLOROFORM (13C) CHLOROFORM (13C) 31717-44-9 CHCl3
1,3-DINONADECANOIN 1,3-DINONADECANOIN 372490-74-9 C41H80O5
BACOPASAPONIN C BACOPASAPONIN C 178064-13-6 C46H74O17
4-fluoro-α-methylbenzeneethanamine  hydrochloride 4-fluoro-α-methylbenzeneethanamine hydrochloride 64609-06-9 C9H13ClFN
Tetramisole-d5 Hydrochloride Tetramisole-d5 Hydrochloride 1173021-85-6 C11H13ClN2S
alpha-[2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol alpha-[2-Fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl]-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol 871550-15-1 C15H14FN9O
1-(3-Chlorophenyl)-5-isopropylbiguanide Hydrochloride 1-(3-Chlorophenyl)-5-isopropylbiguanide Hydrochloride 1071546-52-5 C11H17Cl2N5
ChlorproMazine-d6 Hydrochloride ChlorproMazine-d6 Hydrochloride 1228182-46-4 C17H20Cl2N2S
Methyl [[2-chloro-5-[(1E)-1-[[(6-Methyl-2-pyridinyl)Methoxy]iMino]ethyl]phenyl]Methyl]carbaMate Methyl [[2-chloro-5-[(1E)-1-[[(6-Methyl-2-pyridinyl)Methoxy]iMino]ethyl]phenyl]Methyl]carbaMate 799247-52-2 C18H20ClN3O3
MICROCYSTIN YR MICROCYSTIN YR 101064-48-6 C52H72N10O13
PICOLINAFEN PICOLINAFEN 137641-05-5 C19H12F4N2O2
(1S,2S)-(+)-PSEUDOEPHEDRINE-D3 HCL (N-METHYL-D3) (1S,2S)-(+)-PSEUDOEPHEDRINE-D3 HCL (N-METHYL-D3) 284665-25-4 C10H16ClNO
METICRANE METICRANE 1084-65-7 C10H13NO4S2
6-ACETYLMORPHINE 6-ACETYLMORPHINE 2784-73-8 C19H21NO4
CCMP SODIUM SALT CCMP SODIUM SALT 54925-33-6 C9H11N3NaO7P
BEFLUBUTAMID BEFLUBUTAMID 113614-08-7 C18H17F4NO2
2,3,5,6-TETRACHLOROANISOLE 2,3,5,6-TETRACHLOROANISOLE 6936-40-9 C7H4Cl4O
FAMPROFAZONE FAMPROFAZONE 22881-35-2 C24H31N3O
LINALYL ANTHRANILATE LINALYL ANTHRANILATE 7149-26-0 C17H23NO2
NEOSOLANIOL NEOSOLANIOL 36519-25-2 C19H26O8
DI-N-PENTYL PHTHALATE-D4 DI-N-PENTYL PHTHALATE-D4 358730-89-9 C18H22D4O4
2,2',4,4',6-PENTABROMODIPHENYL ETHER 2,2',4,4',6-PENTABROMODIPHENYL ETHER 189084-64-8 C12H5Br5O
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