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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
BENZO(B)NAPHTHO(1,2-D)THIOPHENE BENZO(B)NAPHTHO(1,2-D)THIOPHENE 205-43-6 C16H10S
METHOXYPHENONE METHOXYPHENONE 41295-28-7 C16H16O2
5-METHYLCHRYSENE 5-METHYLCHRYSENE 3697-24-3 C19H14
4-CYANO-TEMPO 4-CYANO-TEMPO 38078-71-6 C10H17N2O*
DCU DCU 116-52-9 C5H6Cl6N2O3
NALBUPHINE HYDROCHLORIDE NALBUPHINE HYDROCHLORIDE 23277-43-2 C21H28ClNO4
ISOSORBIDE 2-MONONITRATE ISOSORBIDE 2-MONONITRATE 16106-20-0 C6H9NO6
AROCLOR 1016, 1X5ML, TRANSFORMER OIL 50M G/KG AROCLOR 1016, 1X5ML, TRANSFORMER OIL 50M G/KG 12674-11-2 C12H7Cl3
2,2',4,4'-TETRABROMODIPHENYL ETHER 2,2',4,4'-TETRABROMODIPHENYL ETHER 5436-43-1 C12H6Br4O
MEPHOSFOLAN MEPHOSFOLAN 950-10-7 C8H16NO3PS2
N-DesMethyl DiphenhydraMine Hydrochloride N-DesMethyl DiphenhydraMine Hydrochloride 53499-40-4 C16H20ClNO
Ipratropium bromide monohydrate Ipratropium bromide monohydrate 66985-17-9 C20H30NO3.Br.H2O
(3S,4S)-3-HEXYL-4-[(R)-2-(HYDROXYTRIDECYL)]OXETAN-2-ONE (3S,4S)-3-HEXYL-4-[(R)-2-(HYDROXYTRIDECYL)]OXETAN-2-ONE 104872-06-2 C22H42O3
cucurbitacins cucurbitacins 60137-06-6 C30H42O6
4-(4-Chlorophenyl)-2-pyrrolidinone 4-(4-Chlorophenyl)-2-pyrrolidinone 22518-27-0 C10H10ClNO
Halofuginone hydrobromide Halofuginone hydrobromide 64924-67-0 C16H17BrClN3O3.HBr
2-ALLYL-4-PENTENOIC ACID 2-ALLYL-4-PENTENOIC ACID 99-67-2 C8H12O2
Mandipropamid Mandipropamid 374726-62-2 C23H22ClNO4
Mabuterolhydrochloride Mabuterolhydrochloride 54240-36-7 C13H18ClF3N2O.HCl
BUTOCARBOXIM BUTOCARBOXIM 34681-10-2 C7H14N2O2S
11[6H]-[3-(METHYLAMINO)PROPYLIDENE]DIBENZ[B,E]OXEPINE HYDROCHLORIDE 11[6H]-[3-(METHYLAMINO)PROPYLIDENE]DIBENZ[B,E]OXEPINE HYDROCHLORIDE 2887-91-4 C18H20ClNO
METHYL HEXACOSANOATE METHYL HEXACOSANOATE 5802-82-4 C27H54O2
DODECANOIC-D23 ACID DODECANOIC-D23 ACID 59154-43-7 C12HD23O2
IPROVALICARB IPROVALICARB 140923-17-7 C18H28N2O3
ORBENCARB ORBENCARB 34622-58-7 C12H16ClNOS
4-[2-(DIMETHYLAMINO)ETHYLAMINOSULFONYL]-7-CHLORO-2,1,3-BENZOXADIAZOLE 4-[2-(DIMETHYLAMINO)ETHYLAMINOSULFONYL]-7-CHLORO-2,1,3-BENZOXADIAZOLE 664985-43-7 C10H13ClN4O3S
BROMODICHLOROACETIC ACID BROMODICHLOROACETIC ACID 71133-14-7 C2HBrCl2O2
2,3,4,5-TETRACHLOROANILINE 2,3,4,5-TETRACHLOROANILINE 634-83-3 C6H3Cl4N
HT-2 TOXIN HT-2 TOXIN 26934-87-2 C22H32O8
COCAINE COCAINE 50-36-2 C17H21NO4
AROCLOR 1260, 1X1ML, ISO, 1000UG/ML AROCLOR 1260, 1X1ML, ISO, 1000UG/ML 11096-82-5 C12H4Cl6
Prothioconazole Prothioconazole 178928-70-6 C14H15Cl2N3OS
BACOSIDE A3(P) BACOSIDE A3(P) 157408-08-7 C47H76O18
METHYL DIBROMOACETATE, 50MG, NEAT METHYL DIBROMOACETATE, 50MG, NEAT 6482-26-4 C3H4Br2O2
2-NP-AHD 2-NP-AHD 623145-57-3 C10H8N4O4
(+/-)-GEOSMIN (+/-)-GEOSMIN 16423-19-1 C12H22O
EC 2.3.2.2 EC 2.3.2.2 9046-27-9
2,4,5-T-METHYL ESTER 2,4,5-T-METHYL ESTER 1928-37-6 C9H7Cl3O3
DIOFENOLAN DIOFENOLAN 63837-33-2 C18H20O4
PROPYLENE GLYCOL DILAURATE PROPYLENE GLYCOL DILAURATE 22788-19-8 C27H52O4
ALODAN ALODAN 2550-75-6 C9H6Cl8
KETOPROFEN-D3 KETOPROFEN-D3 159490-55-8 C16H14O3
2,4,5-T-1-OCTYL ESTER 2,4,5-T-1-OCTYL ESTER 2630-15-1 C16H21Cl3O3
4-(METHYL-D3-NITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL 4-(METHYL-D3-NITROSAMINO)-1-(3-PYRIDYL)-1-BUTANOL 1020719-61-2 C10H12D3N3O2
COAGULATION FACTOR VII, HUMAN COAGULATION FACTOR VII, HUMAN 9001-25-6
4-METHYLCHRYSENE 4-METHYLCHRYSENE 3351-30-2 C19H14
EDDP PERCHLORATE EDDP PERCHLORATE 66729-78-0 C20H24ClNO4
N-DESMETHYLFLUNITRAZEPAM N-DESMETHYLFLUNITRAZEPAM 2558-30-7 C15H10FN3O3
AROCHLOR 1232 AROCHLOR 1232 11100-14-4
PENTANOCHLOR PENTANOCHLOR 2307-68-8 C13H18ClNO
Bethoxazin Bethoxazin 163269-30-5 C11H9NO2S2
1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol 1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol 5196-20-3 C8H9NO2
metomidate metomidate 5377-20-8 C13H14N2O2
4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidyl decanoate 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidyl decanoate 74050-97-8 C31H41ClFNO3
CHLORDIAZEPOXIDE-D5 CHLORDIAZEPOXIDE-D5 65891-81-8 C16H14ClN3O
GLYBURIDE   RELATED   COMPOUND   B   (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS) GLYBURIDE RELATED COMPOUND B (25 MG) (METHYL-[[4-[2-[(5-CHLORO-2-METHOXYBENZOYL)-AMINO]ETHYL]PHENYL]SULFONYL]CARBAMATE) (AS) 21165-77-5 C18H19ClN2O6S
Chitosan Hydrochloride Chitosan Hydrochloride 70694-72-3
Calcipotriol Monohydrate Calcipotriol Monohydrate 147657-22-5 C27H42O4
Endo-3-amine-9-methyl-9-azabicyclo[3,3,1]nonane Endo-3-amine-9-methyl-9-azabicyclo[3,3,1]nonane 107007-95-4 C17 H22 N4 O
4-THUJANOL 4-THUJANOL 546-79-2 C10H18O
FLUOROIMIDE FLUOROIMIDE 41205-21-4 C10H4Cl2FNO2
3-(2-CHLORO-4-METHYLBENZOYL)-4-PHENYLTHIOBICYCLO[3,2,1]OCT-2-EN-4-ONE 3-(2-CHLORO-4-METHYLBENZOYL)-4-PHENYLTHIOBICYCLO[3,2,1]OCT-2-EN-4-ONE 156963-66-5 C22H19ClO4S2
Methasulfocarb Methasulfocarb 66952-49-6 C9H11NO4S2
6-aminocarbovir 6-aminocarbovir 124752-25-6 C11H14N6O
dihydromevinolin dihydromevinolin 77517-29-4 C24H38O5
1,2-DIPHENYL-3-METHYL-4-[METHYLAMINO]-2-BUTYL PROPIONATE MALEATE SALT 1,2-DIPHENYL-3-METHYL-4-[METHYLAMINO]-2-BUTYL PROPIONATE MALEATE SALT 38910-73-5 C25H31NO6
PACLITAXEL C PACLITAXEL C 153415-45-3 C46H57NO14
2,4-Diamino-6-phenyl-7-pteridinol 2,4-Diamino-6-phenyl-7-pteridinol 19152-93-3 C12H10N6O
1-HYDROXYCLOBUT-1-ENE-3,4-DIONE SODIUM SALT 1-HYDROXYCLOBUT-1-ENE-3,4-DIONE SODIUM SALT 71376-34-6 C4H3NaO3
2-(Carbamoyloxymethyl)-1-methyl-d3-5-nitro-imidazole 2-(Carbamoyloxymethyl)-1-methyl-d3-5-nitro-imidazole 1015855-87-4 C6D3H5N4O4
Dimethenamid-d3 Dimethenamid-d3 1246816-31-8 C12H18ClNO2S
SEBUTHYLAZINE-DESETHYL SEBUTHYLAZINE-DESETHYL 37019-18-4 C7H12ClN5
SPIROTETRAMAT SPIROTETRAMAT 203313-25-1 C21H27NO5
Tapentadol O-β-D-Glucuronide Tapentadol O-β-D-Glucuronide 1300037-86-8 C20H31NO7
2,4,5-T-2-ETHYLHEXYL ESTER 2,4,5-T-2-ETHYLHEXYL ESTER 1928-47-8 C16H21Cl3O3
2,5-DiMethyl Celecoxib 2,5-DiMethyl Celecoxib 457639-26-8 C18H16F3N3O2S
2-(MethylaMino)-3',4'-(Methylenedioxy)valerophenone Hydrochloride 2-(MethylaMino)-3',4'-(Methylenedioxy)valerophenone Hydrochloride 17763-01-8 C13H18ClNO3
FaMotidine AMide IMpurity FaMotidine AMide IMpurity 76824-16-3 C8H13N5OS2
Tapentadol O-Sulfate Tapentadol O-Sulfate 1300037-87-9 C14H23NO4S
1-[3-(DIMETHYLAMINO)PROPYL]-1-(4-FLUOROPHENYL)-1,3-DIHYDRO-5-ISOBENZOFURANCARBOXAMIDE 1-[3-(DIMETHYLAMINO)PROPYL]-1-(4-FLUOROPHENYL)-1,3-DIHYDRO-5-ISOBENZOFURANCARBOXAMIDE 64372-56-1 C20H23FN2O2
Trimethoprim Related Compound A (25 mg) (4-amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-2-ol) (AS) Trimethoprim Related Compound A (25 mg) (4-amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-2-ol) (AS) 60729-91-1 C14H17N3O4
BMS 564929 BMS 564929 627530-84-1 C14H12ClN3O3
BENZO(C)CHRYSENE BENZO(C)CHRYSENE 194-69-4 C22H14
DIBENZO(A,J)ANTHRACENE DIBENZO(A,J)ANTHRACENE 224-41-9 C22H14
DELPHINIDIN-3-GALACTOSIDE DELPHINIDIN-3-GALACTOSIDE 28500-00-7 C21H21O12.Cl
DMST DMST 66840-71-9 C9H14N2O2S
CHLORTHION CHLORTHION 500-28-7 C8H9ClNO5PS
HEXATETRACONTANE HEXATETRACONTANE 7098-24-0 C46H94
4-(BUTYLAMINO)-1-ETHYL-6-METHYL 1H-PYRAZOLO[3,4B]PYRIDINE-5-ETHYLCARBOXYLATE HYDROCHLORIDE 4-(BUTYLAMINO)-1-ETHYL-6-METHYL 1H-PYRAZOLO[3,4B]PYRIDINE-5-ETHYLCARBOXYLATE HYDROCHLORIDE 41094-88-6 C16H24N4O2
SENKIRKIN SENKIRKIN 2318-18-5 C19H27NO6
2-DIETHYLAMINOETHYL 2-PHENYLBUTYRATE CITRATE SALT 2-DIETHYLAMINOETHYL 2-PHENYLBUTYRATE CITRATE SALT 13900-12-4 C22H33NO9
HENTETRACONTANE HENTETRACONTANE 7194-87-8 C41H84
HYDROCODONE BITARTRATE HYDROCODONE BITARTRATE 143-71-5 C22H27NO9
DELTA-8-THC DELTA-8-THC 5957-75-5 C21H30O2
13-CIS-ACITRETIN 13-CIS-ACITRETIN 69427-46-9 C21H26O3
YTTERBIUM(III) IONOPHORE I YTTERBIUM(III) IONOPHORE I 125110-14-7 C16H17N5O8S2
SQ-NHS* SQ-NHS* 154161-81-6 C34H32ClN3O6
CITALOPRAM  RELATED  COMPOUND  F  (200 MG) (DIMETHYL-(1-METHYL-3,3-DIPHENYL-ALLYL)-AMINE HYDROCHLORIDE) CITALOPRAM RELATED COMPOUND F (200 MG) (DIMETHYL-(1-METHYL-3,3-DIPHENYL-ALLYL)-AMINE HYDROCHLORIDE) 55011-89-7 C18H22ClN
DIHEPTYLTIN DICHLORIDE DIHEPTYLTIN DICHLORIDE 74340-12-8 C14H30Cl2Sn
2,4,4'-TRIBROMODIPHENYL ETHER 2,4,4'-TRIBROMODIPHENYL ETHER 41318-75-6 C12H7Br3O
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