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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
LEVOCARNITINE RELATED COMPOUND A (100 MG) (3-CARBOXY-N,N,N-TRIMETHYL-2-PROPEN-1-AMINIUM CHLORIDE) LEVOCARNITINE RELATED COMPOUND A (100 MG) (3-CARBOXY-N,N,N-TRIMETHYL-2-PROPEN-1-AMINIUM CHLORIDE) 6538-82-5 C7H13ClNO2
T-2 TRIOL T-2 TRIOL 34114-98-2 C20H30O7
4-BENZYLOXY-ALPHA-CYANOCINNAMIC ACID 4-BENZYLOXY-ALPHA-CYANOCINNAMIC ACID 162882-36-2 C17H13NO3
4 FUEL OIL 4 FUEL OIL 68476-31-3
6-ACETYLMORPHINE-D6 6-ACETYLMORPHINE-D6 152477-90-2 C19H15D6NO4
NONANAL (DNPH DERIVATIVE) NONANAL (DNPH DERIVATIVE) 2348-19-8 C15H22N4O4
PENTOBARBITAL-D5 PENTOBARBITAL-D5 52944-66-8 C11H18N2O3
DIBENZ[C,H]ACRIDINE DIBENZ[C,H]ACRIDINE 224-53-3 C21H13N
2-PENTYL BUTYRATE 2-PENTYL BUTYRATE 60415-61-4 C9H18O2
1-HYDROXY-2,2,5,5-TETRAMETHYL-3-IMIDAZOLINE-4-CARBOXAL-DEHYDE HYDRAZONE-3-OXIDE 1-HYDROXY-2,2,5,5-TETRAMETHYL-3-IMIDAZOLINE-4-CARBOXAL-DEHYDE HYDRAZONE-3-OXIDE 51973-32-1 C8H16N4O2
PROPACHLOR ESA SODIUM SALT PROPACHLOR ESA SODIUM SALT 947601-88-9 C11H14NNaO4S
DINOTERB-BIS(2-HYDROXY ETHYL) AMMONIUM DINOTERB-BIS(2-HYDROXY ETHYL) AMMONIUM C14H23N3O7
Fuels, diesel, no. 2 Fuels, diesel, no. 2 68476-34-6
Levomepromazine hydrochloride Levomepromazine hydrochloride 1236-99-3 C19H24N2OS.ClH
octahydro-2-nitrosocyclopenta[c]pyrrole octahydro-2-nitrosocyclopenta[c]pyrrole 54786-86-6 C7H12N2O
N-(2-ETHYL-6-METHYLPHENYL)-2-HYDROXYACETAMIDE N-(2-ETHYL-6-METHYLPHENYL)-2-HYDROXYACETAMIDE 97055-05-5 C11H15NO2
Clazuril Clazuril 101831-36-1 C17H10Cl2N4O2
Citalopram Related Compound E Citalopram Related Compound E
(9S,13S,14S)-3-METHOXYMORPHINAN HYDROCHLORIDE (9S,13S,14S)-3-METHOXYMORPHINAN HYDROCHLORIDE 1087-69-0 C17H24ClNO
NORMEPERIDINE-D4 NORMEPERIDINE-D4 160227-47-4 C14H15D4NO2
1-Cyano-3-isopropylguanidine1-Cyano-3-isopropylguanidine 44830-55-9 C5H10N4
4,8,12-Trimethyl-1-(1-methylethyl)-3,7,11-cyclotetradecatrien-1-ol 4,8,12-Trimethyl-1-(1-methylethyl)-3,7,11-cyclotetradecatrien-1-ol 67814-27-1 C20H34O
LevetiracetaM IMpurity B LevetiracetaM IMpurity B 358629-47-7 C8H12N2O2
Acetamiprid D3 Acetamiprid D3 1353869-35-8 C10H11ClN4
(±)-Metanephrine-D3 HCl (±)-Metanephrine-D3 HCl
Tioconazole Related Compound A (25 mg) (1-[2,4-Dichloro-beta-[(3-thenyl)-oxy]phenethyl]imidazole hydrochloride) Tioconazole Related Compound A (25 mg) (1-[2,4-Dichloro-beta-[(3-thenyl)-oxy]phenethyl]imidazole hydrochloride) 61709-33-9 C16H15Cl3N2OS
Loratadine EP IMpurity F Loratadine EP IMpurity F 125743-80-8 C22H24ClFN2O2
(S)-(-)-Nicotine-d4 (S)-(-)-Nicotine-d4 284685-07-0 C10H14N2
N-Acetyl Retigabine N-Acetyl Retigabine 229970-68-7 C15H16FN3O
IsopyrazaM IsopyrazaM 881685-58-1 C20H23F2N3O
3,4-DICHLOROPHENYL DIPROPIONAMIDE 3,4-DICHLOROPHENYL DIPROPIONAMIDE 954-24-5 C12H13Cl2NO2
SULFUR-34 SULFUR-34 13965-97-4 S
2,2-BIS[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]PROPANE 2,2-BIS[4-(3-CHLORO-2-HYDROXYPROPOXY)PHENYL]PROPANE 4809-35-2 C21H26Cl2O4
PEONIDIN 3-ARABINOSIDE PEONIDIN 3-ARABINOSIDE 27214-74-0 C21H21ClO10
17ALPHA(H),21ALPHA(H)-HOPANE 17ALPHA(H),21ALPHA(H)-HOPANE 13849-96-2 C30H52
POTASSIUM THIOCYANATE-15N POTASSIUM THIOCYANATE-15N 160350-71-0 CKNS
MORPHINE SULFATE NARCOTIC ANALGESIC MORPHINE SULFATE NARCOTIC ANALGESIC 64-31-3 C18H25NO8S
THROMBOPLASTIN FROM RABBIT BRAIN, 1 X 40  MG THROMBOPLASTIN FROM RABBIT BRAIN, 1 X 40 MG 72162-96-0
S(+)-3 4-MDMA HCL S(+)-3 4-MDMA HCL 64057-70-1 C11H16ClNO2
N,N'-(METHYLENEDIPHENYLENE)BIS(4-(2-PYRIDINYL)-1-PIPERAZINECARBOXAMIDE),1X1ML N,N'-(METHYLENEDIPHENYLENE)BIS(4-(2-PYRIDINYL)-1-PIPERAZINECARBOXAMIDE),1X1ML 72375-27-0 C26H38N8O2
GLIMEPIRIDE   RELATED  COMPOUND  C  (20 MG) (GLIMEPIRIDE URETHANE) GLIMEPIRIDE RELATED COMPOUND C (20 MG) (GLIMEPIRIDE URETHANE) 119018-30-3 C18H23N3O6S
INSULIN LISPRO (5.97 MG) INSULIN LISPRO (5.97 MG) 133107-64-9 C257H383N65O77S6
TRAMADOL IMPURITY E TRAMADOL IMPURITY E C16H25NO2
FLUCONAZOLE IMPURITY B FLUCONAZOLE IMPURITY B C13H12F2N6O
DDGTP SODIUM SALT DDGTP SODIUM SALT 1135689-76-7 C10H15N5NaO12P3
BROMOMETHANE-D3 BROMOMETHANE-D3 1111-88-2 CBrD3
8-CHLORO-2,3,4,5-TETRAHYDRO-5-PHENYL-1H-3-BENZAZEPIN-7-OL-(5R) 8-CHLORO-2,3,4,5-TETRAHYDRO-5-PHENYL-1H-3-BENZAZEPIN-7-OL-(5R) 106648-57-1 C16H16ClNO
2,6-DIMETHYL-6-HEPTEN-2-OL 2,6-DIMETHYL-6-HEPTEN-2-OL 32779-58-1 C9H18O
2-methyl-5-nitro-1H-imidazole-1-propanol monohydrochloride 2-methyl-5-nitro-1H-imidazole-1-propanol monohydrochloride 70028-95-4 C7H12ClN3O3
rac Metoprolol-d7 rac Metoprolol-d7 959787-96-3 C15H25NO3
ChlorproMazine Sulfoxide ChlorproMazine Sulfoxide 969-99-3 C17H19ClN2OS
HYDRANAL-METHANOL DRY HYDRANAL-METHANOL DRY
[(3E)-3-[[4-[(Z)-[7,7-dimethyl-3-oxo-4-(sulfomethyl)norbornan-2-yliden e]methyl]phenyl]methylidene]-7,7-dimethyl-2-oxo-norbornan-1-yl]methane sulfonic acid [(3E)-3-[[4-[(Z)-[7,7-dimethyl-3-oxo-4-(sulfomethyl)norbornan-2-yliden e]methyl]phenyl]methylidene]-7,7-dimethyl-2-oxo-norbornan-1-yl]methane sulfonic acid 92761-26-7 C28H34O8S2
Fosinopril Related Compound B Fosinopril Related Compound B
all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6 all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6 25182-74-5 C22H34O2
trans,trans-9,11-Octadecadienoicacid trans,trans-9,11-Octadecadienoicacid 544-71-8 C18H32O2
BROMOCHLOROBUTEROL HYDROCHLORIDE BROMOCHLOROBUTEROL HYDROCHLORIDE 78982-84-0 C12H19BrCl2N2O
Promethazine-d6 Hydrochloride Salt Promethazine-d6 Hydrochloride Salt 1189947-02-1 C17H21ClN2S
Naproxen-d3 Naproxen-d3 958293-79-3 C14H14O3
4-Nitro-2-phenoxyaniline 4-Nitro-2-phenoxyaniline 5422-92-4 C12H10N2O3
MEPERIDINE (D4) MEPERIDINE (D4) 53484-73-4 C15H17D4NO2
2-{2-[4-(3’,6’-Dimethyl-3’-heptyl)phenoxy]ethoxy}ethanol 2-{2-[4-(3’,6’-Dimethyl-3’-heptyl)phenoxy]ethoxy}ethanol 1119449-38-5 C19H32O3
Shatavarin IV Shatavarin IV 84633-34-1 C45H74O17
SulfaMethoxazole N4-glucoside SulfaMethoxazole N4-glucoside 119691-75-7 C16H21N3O8S
Trimethoprim Related Compound B (25 mg) (2,4-diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanone) (AS) Trimethoprim Related Compound B (25 mg) (2,4-diaminopyrimidin-5-yl)(3,4,5-trimethoxyphenyl)methanone) (AS) 30806-86-1 C14H16N4O4
4-Hydroxy-tetraMisole 4-Hydroxy-tetraMisole 6649-26-9 C11H12N2OS
Oxibendazole-aMine-D7 Oxibendazole-aMine-D7 1448346-35-7 C10H13N3O
5-(4-Morpholinylmethyl-d<sub>2</sub>)-3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinone-4,4,5-d<sub>3</sub> 5-(4-Morpholinylmethyl-d2)-3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinone-4,4,5-d3 1015855-64-7 C13H16N4O6
HYDRANAL-LIPOSOLVER CM HYDRANAL-LIPOSOLVER CM
C2-C6 OLEFINS C2-C6 OLEFINS
HYDRANAL(R)-SOLVENT HYDRANAL(R)-SOLVENT
CARBON DISULFIDE (13C) CARBON DISULFIDE (13C) 30860-31-2 CS2
FISKE-SUBBAROW REDUCER FISKE-SUBBAROW REDUCER
DOCOSANOIC ACID TRYPTAMIDE DOCOSANOIC ACID TRYPTAMIDE 7367-79-5 C32H54N2O
Delta9-Tetrahydrocannabinolic acid A solution Delta9-Tetrahydrocannabinolic acid A solution 23978-85-0 C22H30O4
DIFLUFENZOPYR SODIUM SALT DIFLUFENZOPYR SODIUM SALT 109293-98-3 C15H11F2N4O3.Na
CHLORBENSID SULFOXIDE PESTANAL  100 MG CHLORBENSID SULFOXIDE PESTANAL 100 MG 7047-28-1 C13H10Cl2OS
6 FUEL OIL 6 FUEL OIL 68553-00-4
(+/-)-BUTACLAMOL HCL (+/-)-BUTACLAMOL HCL 36504-94-6 C25H31NO.ClH
CYLINDROSPERMOPSIN CYLINDROSPERMOPSIN 143545-90-8 C15H21N5O7S
S(-)-CATHINONE HYDROCHLORIDE S(-)-CATHINONE HYDROCHLORIDE 71031-15-7 C9H11NO
OLEIC-13C18 ACID OLEIC-13C18 ACID 287100-82-7 C18H34O2
(-)-DELTA-9-THC (D3) (-)-DELTA-9-THC (D3) 81586-39-2 C21H30O2
bis(8-methylnonyl) phthalate bis(8-methylnonyl) phthalate 89-16-7 C28H46O4
4'-(pyrimidin-2-ylsulphamoyl)acetanilide 4'-(pyrimidin-2-ylsulphamoyl)acetanilide 127-74-2 C12H12N4O3S
PROFOXYDIM LITHIUM SALT, PESTANAL PROFOXYDIM LITHIUM SALT, PESTANAL 281664-76-4 C24H33ClLiNO4S
KAFFEESA URE-1,1-DIMETHYLALLYLESTER >95% (HPLC) KAFFEESA URE-1,1-DIMETHYLALLYLESTER >95% (HPLC) 118971-61-2 C14H16O4
2,5-DIMETHOXY-4-(PROPYLTHIO)BENZENEETHANAMINE, YDROCHLORIDE 2,5-DIMETHOXY-4-(PROPYLTHIO)BENZENEETHANAMINE, YDROCHLORIDE 850140-15-7 C13H22ClNO2S
GLYPHOSATE-(PHOSPHONOMETHYL-2-14C) SODIUM SALT GLYPHOSATE-(PHOSPHONOMETHYL-2-14C) SODIUM SALT 130538-98-6 C3H8NO5P
1,3-Palmitin-2-Linolein 1,3-Palmitin-2-Linolein 2442-56-0 C53H98O6
Fosinopril Related Compound D Fosinopril Related Compound D 1356353-41-7 C30H47NNaO7P
1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI) 1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI) 4531-54-8 C4H6N4O2
3-Isopropyl-d7-1H-2,1,3-benzothiadiazin-4(3H)-one  2,2-dioxide 3-Isopropyl-d7-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide 131842-77-8 C10D7H5N2O3S
(+/-)-2,5-DIMETHOXY-4-BROMO-AMPHETAMINE HYDROBROMIDE (+/-)-2,5-DIMETHOXY-4-BROMO-AMPHETAMINE HYDROBROMIDE 53581-53-6 C11H17Br2NO2
2alpha,19alpha,23-Trihydroxyoleanolic acid 2alpha,19alpha,23-Trihydroxyoleanolic acid 58880-25-4 C30H48O6
rac-3,4-DiMethyl Methcathinone Hydrochloride rac-3,4-DiMethyl Methcathinone Hydrochloride 1081772-06-6 C12H18ClNO
Thiencarbazone-methyl Thiencarbazone-methyl 317815-83-1 C12H14N4O7S2
Proguanil Related Compound C (25 mg) (1,5-bis(4-chlorophenyl)biguanide hydrochloride) Proguanil Related Compound C (25 mg) (1,5-bis(4-chlorophenyl)biguanide hydrochloride) 13590-98-2 C14H14Cl3N5
[2S-[1[R*(R*)],2α,3aβ,6aβ]]-1-[2-[[3-Cyclohexyl-1-(ethoxycarbonyl)propyl]aMino]-1-oxoprop [2S-[1[R*(R*)],2α,3aβ,6aβ]]-1-[2-[[3-Cyclohexyl-1-(ethoxycarbonyl)propyl]aMino]-1-oxoprop 99742-35-5 C23H38N2O5
1-[(2S)-3-BroMo-2-Methyl-1-oxopropyl]-L-proline 1-[(2S)-3-BroMo-2-Methyl-1-oxopropyl]-L-proline 80629-35-2 C9H14BrNO3
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