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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
25-HYDROXYVITAMIN D2 25-HYDROXYVITAMIN D2 21343-40-8 C28H44O2
3-(4-METHYLBENZYLIDENE)CAMPHOR 3-(4-METHYLBENZYLIDENE)CAMPHOR 36861-47-9 C18H22O
(+/-)-alpha-Lipoamide (+/-)-alpha-Lipoamide 940-69-2 C8H15NOS2
Cellulose acetate phthalate Cellulose acetate phthalate 9004-38-0 C116H116O64
PHENTERMINE HYDROCHLORIDE PHENTERMINE HYDROCHLORIDE 1197-21-3 C10H16ClN
Valencene Valencene 4630-07-3 C15H24
Terconazole Terconazole 67915-31-5 C26H31Cl2N5O3
Benoxacor Benoxacor 98730-04-2 C11H11Cl2NO2
Cymiazole Cymiazole 61676-87-7 C12H14N2S
ANTAZOLINE PHOSPHATE ANTAZOLINE PHOSPHATE 154-68-7 C17H22N3O4P
N-NITROSOPYRROLIDINE N-NITROSOPYRROLIDINE 930-55-2 C4H8N2O
PONCEAU SX PONCEAU SX 4548-53-2 C18H17N2NaO7S2
Nandrolone 17-propionate Nandrolone 17-propionate 7207-92-3 C21H30O3
N-NITROSODIETHANOLAMINE N-NITROSODIETHANOLAMINE 1116-54-7 C4H10N2O3
2-CHLORO-4-NITROBENZAMIDE 2-CHLORO-4-NITROBENZAMIDE 3011-89-0 C7H5ClN2O3
2,2,2-TRIFLUORO-N-PHENYLACETAMIDE 2,2,2-TRIFLUORO-N-PHENYLACETAMIDE 404-24-0 C8H6F3NO
CHLORDIAZEPOXIDE HYDROCHLORIDE CHLORDIAZEPOXIDE HYDROCHLORIDE 438-41-5 C16H15Cl2N3O
PTEROIC ACID PTEROIC ACID 119-24-4 C14H12N6O3
Quinine bisulfate Quinine bisulfate 549-56-4 C40H50N4O8S
Parbendazole Parbendazole 14255-87-9 C13H17N3O2
Prednicarbate Prednicarbate 73771-04-7 C27H36O8
3-Carboxy-2,2,5,5-tetraMethylpyrrolidine 1-Oxyl Free Radical 3-Carboxy-2,2,5,5-tetraMethylpyrrolidine 1-Oxyl Free Radical 2154-68-9 C9H16NO3*
Methyl 4-acetamido-2-methoxybenzoate Methyl 4-acetamido-2-methoxybenzoate 4093-29-2 C11H13NO4
D-Ephedrine hydrochloride D-Ephedrine hydrochloride 24221-86-1 C10H16ClNO
PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER PHTHALIC ACID MONO-2-ETHYLHEXYL ESTER 4376-20-9 C16H22O4
5-METHOXYTRYPTOPHOL 5-METHOXYTRYPTOPHOL 712-09-4 C11H13NO2
Diflorasone diacetate Diflorasone diacetate 33564-31-7 C26H32F2O7
Hexamidine diisethionate Hexamidine diisethionate 659-40-5 C22H32N4O6S
DIELDRIN DIELDRIN 60-57-1 C12H8Cl6O
Dihydroergotoxine mesylate Dihydroergotoxine mesylate 8067-24-1 C20H29N3O5S
DL-TROPIC ACID DL-TROPIC ACID 552-63-6 C9H10O3
2,4,6-Tris(trifluoromethyl)-1,3,5-triazine 2,4,6-Tris(trifluoromethyl)-1,3,5-triazine 368-66-1 C6F9N3
CYCLOPENTOLATE HYDROCHLORIDE CYCLOPENTOLATE HYDROCHLORIDE 5870-29-1 C17H26ClNO3
4-Isopropylthioxanthone 4-Isopropylthioxanthone 83846-86-0 C16H14OS
(-)-COTININE (-)-COTININE 486-56-6 C10H12N2O
17-BETA-ESTRADIOL 3,17-DIPROPIONATE 17-BETA-ESTRADIOL 3,17-DIPROPIONATE 113-38-2 C24H32O4
Benperidol Benperidol 2062-84-2 C22H24FN3O2
ISOXADIFEN-ETHYL ISOXADIFEN-ETHYL 163520-33-0 C18H17NO3
ISOBARBITURIC ACID ISOBARBITURIC ACID 496-76-4 C4H4N2O3
1,7-Dimethylxanthine 1,7-Dimethylxanthine 611-59-6 C7H8N4O2
3-MERCAPTOISOBUTYRIC ACID 3-MERCAPTOISOBUTYRIC ACID 26473-47-2 C4H8O2S
BENZO[E]PYRENE BENZO[E]PYRENE 192-97-2 C20H12
Cybutryne Cybutryne 28159-98-0 C11H19N5S
Sodium m-arsenite Sodium m-arsenite 7784-46-5 AsO2.Na
1-Pentyl-3-(1-naphthoyl)indole 1-Pentyl-3-(1-naphthoyl)indole 209414-07-3 C24H23NO
Tapentadol Hydrochloride Tapentadol Hydrochloride 175591-09-0 C14H24ClNO
MONOBUTYL PHTHALATE MONOBUTYL PHTHALATE 131-70-4 C12H14O4
PENTACOSANOIC ACID PENTACOSANOIC ACID 506-38-7 C25H50O2
N-NITROSODI-N-PROPYLAMINE N-NITROSODI-N-PROPYLAMINE 621-64-7 C6H14N2O
4-Deoxypyridoxine hydrochloride 4-Deoxypyridoxine hydrochloride 148-51-6 C8H12ClNO2
1-Methyl-5-nitro-1H-imidazole-2-methanol 1-Methyl-5-nitro-1H-imidazole-2-methanol 936-05-0 C5H7N3O3
Chlorflurenol-methyl Chlorflurenol-methyl 2536-31-4 C15H11ClO3
Pemetrexed Disodium Heptahydrate Pemetrexed Disodium Heptahydrate 357166-29-1 C20H24N5NaO7
AMMELINE AMMELINE 645-92-1 C3H5N5O
CORTICOSTERONE 21-ACETATE CORTICOSTERONE 21-ACETATE 1173-26-8 C23H32O5
METHYL MELISSATE METHYL MELISSATE 629-83-4 C31H62O2
Safflower oil Safflower oil 8001-23-8 NULL
2-(1-NAPHTHYL)-5-PHENYLOXAZOLE 2-(1-NAPHTHYL)-5-PHENYLOXAZOLE 846-63-9 C19H13NO
DICYCLOMINE HYDROCHLORIDE DICYCLOMINE HYDROCHLORIDE 67-92-5 C19H36ClNO2
2,9-DIMETHYL-1,10-PHENANTHROLINE HEMIHYDRATE 2,9-DIMETHYL-1,10-PHENANTHROLINE HEMIHYDRATE 34302-69-7 C14H14N2O
7-(2-HYDROXYETHYL)THEOPHYLLINE 7-(2-HYDROXYETHYL)THEOPHYLLINE 519-37-9 C9H12N4O3
TERPIN MONOHYDRATE TERPIN MONOHYDRATE 2451-01-6 C10H22O3
DISPERSE ORANGE 3 DISPERSE ORANGE 3 730-40-5 C12H10N4O2
PARAOXON PARAOXON 311-45-5 C10H14NO6P
2,3,4-TRICHLOROPHENOL 2,3,4-TRICHLOROPHENOL 15950-66-0 C6H3Cl3O
GLIOTOXIN GLIOTOXIN 67-99-2 C13H14N2O4S2
(1R,2R,5R)-(+)-2-Hydroxy-3-pinanone (1R,2R,5R)-(+)-2-Hydroxy-3-pinanone 24047-72-1 C10H16O2
10E,12Z-octadecadienoic acid 10E,12Z-octadecadienoic acid 2420-56-6 C18H32O2
N-(2-Ethylhexyl)-5-norbornene-2,3-dicarboximide N-(2-Ethylhexyl)-5-norbornene-2,3-dicarboximide 113-48-4 C17H25NO2
GLOBULINS, CAT GAMMA GLOBULINS, CAT GAMMA 9007-83-4
N-NITROSOMORPHOLINE N-NITROSOMORPHOLINE 59-89-2 C4H8N2O2
Chlortalidone Chlortalidone 77-36-1 C14H11ClN2O4S
Novaluron Novaluron 116714-46-6 C17H9ClF8N2O4
AFLATOXIN G2 AFLATOXIN G2 7241-98-7 C17H14O7
4-AMINO-2,6-DINITROTOLUENE 4-AMINO-2,6-DINITROTOLUENE 19406-51-0 C7H7N3O4
2-TERT-BUTYL-4-HYDROXYANISOLE 2-TERT-BUTYL-4-HYDROXYANISOLE 88-32-4 C11H16O2
2-BUTYL-2-ETHYL-1,3-PROPANEDIOL 2-BUTYL-2-ETHYL-1,3-PROPANEDIOL 115-84-4 C9H20O2
2,3-Dichloropropionic acid 2,3-Dichloropropionic acid 565-64-0 C3H4Cl2O2
ASTAXANTHIN ASTAXANTHIN 7542-45-2 C40H52O4
N-BUTYL METHANESULPHONATE N-BUTYL METHANESULPHONATE 1912-32-9 C5H12O3S
3-BROMO-2-METHYLPROPIONIC ACID 3-BROMO-2-METHYLPROPIONIC ACID 56970-78-6 C4H7BrO2
2-(4-BIPHENYLYL)-5-PHENYL-1,3,4-OXADIAZOLE 2-(4-BIPHENYLYL)-5-PHENYL-1,3,4-OXADIAZOLE 852-38-0 C20H14N2O
ENDRIN ENDRIN 72-20-8 C12H8Cl6O
VIOLURIC ACID MONOHYDRATE VIOLURIC ACID MONOHYDRATE 26351-19-9 C4H5N3O5
Dibromofluoromethane Dibromofluoromethane 1868-53-7 CHBr2F
TRILINOLEIN TRILINOLEIN 537-40-6 C57H98O6
2,4,5-TRIMETHYLANILINE 2,4,5-TRIMETHYLANILINE 137-17-7 C9H13N
1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE 36507-30-9 C15H12N2O2
SESAMOLIN SESAMOLIN 526-07-8 C20H18O7
3,3'-DIMETHYLNAPHTHIDINE 3,3'-DIMETHYLNAPHTHIDINE 13138-48-2 C22H20N2
Chloropyramine hydrochloride Chloropyramine hydrochloride 6170-42-9 C16H21Cl2N3
AFLATOXIN G1 AFLATOXIN G1 1165-39-5 C17H12O7
1,3-Diethyl-1,3-diphenylurea 1,3-Diethyl-1,3-diphenylurea 85-98-3 C17H20N2O
Flumethasone 21-pivalate Flumethasone 21-pivalate 2002-29-1 C27H36F2O6
Amodiaquin dihydrochloride dihydrate Amodiaquin dihydrochloride dihydrate 6398-98-7 C20H25Cl2N3O2
2-chloro-1,3-butadiene 2-chloro-1,3-butadiene 126-99-8 C4H5Cl
ISOXSUPRINE HYDROCHLORIDE ISOXSUPRINE HYDROCHLORIDE 579-56-6 C18H24ClNO3
Thifensulfuron Thifensulfuron 79277-67-1 C11H11N5O6S2
2,3,5,6-TETRACHLOROPHENOL 2,3,5,6-TETRACHLOROPHENOL 935-95-5 C6H2Cl4O
Nandrolone laurate Nandrolone laurate 26490-31-3 C30H48O3
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