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Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
ETIZOLAM ETIZOLAM 40054-69-1 C17H15ClN4S
3-Pyridyl dimethylcarbamate 3-Pyridyl dimethylcarbamate 51581-32-9 C8H10N2O2
Etifenin Etifenin 63245-28-3 C16H22N2O5
Prednisolone succinate Prednisolone succinate 2920-86-7 C25H32O8
CARAZOLOL HCL CARAZOLOL HCL 57775-29-8 C18H22N2O2
PONCEAU 3R PONCEAU 3R 3564-09-8 C19H19N2NaO7S2
INDENO(1,2,3-C,D)PYRENE INDENO(1,2,3-C,D)PYRENE 193-39-5 C22H12
N-(4-AMINOBUTYL)-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE N-(4-AMINOBUTYL)-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE 89108-46-3 C14H19ClN2O2S
2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide 2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide 33288-71-0 C14H16N4O3S
Clobetasone butyrate Clobetasone butyrate 25122-57-0 C26H32ClFO5
Clopamide Clopamide 636-54-4 C14H20ClN3O3S
3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE 3-CARBAMYL-1-METHYLPYRIDINIUM CHLORIDE 1005-24-9 C7H9ClN2O
7-Amino-3-(1,2,3-triazol-4-ylthio)methyl cephalosporanic acid 7-Amino-3-(1,2,3-triazol-4-ylthio)methyl cephalosporanic acid 37539-03-0 C10H11N5O3S2
1-(2-THIAZOLYLAZO)-2-NAPHTHOL 1-(2-THIAZOLYLAZO)-2-NAPHTHOL 1147-56-4 C13H9N3OS
Nitrosobenzene Nitrosobenzene 586-96-9 C6H5NO
METHYL RICINOLEATE METHYL RICINOLEATE 141-24-2 C19H36O3
FENCHOL FENCHOL 1632-73-1 C10H18O
DEOXYNIVALENOL DEOXYNIVALENOL 51481-10-8 C15H20O6
PHTHALIC ACID MONOBENZYL ESTER PHTHALIC ACID MONOBENZYL ESTER 2528-16-7 C15H12O4
KANAMYCIN ACID SULFATE KANAMYCIN ACID SULFATE 64013-70-3 C18H40N4O19S2
4,4'-Dihydroxytetraphenylmethane 4,4'-Dihydroxytetraphenylmethane 1844-01-5 C25H20O2
GRAM'S IODINE GRAM'S IODINE 12298-68-9 I3K
ISOBUTYRALDEHYDE 2,4-DINITROPHENYLHYDRAZONE ISOBUTYRALDEHYDE 2,4-DINITROPHENYLHYDRAZONE 2057-82-1 C10H12N4O4
CIS-CHLORDANE CIS-CHLORDANE 5103-71-9 C10H6Cl8
AZINPHOS-METHYL AZINPHOS-METHYL 86-50-0 C10H12N3O3PS2
Formoterol fumarate dihydrate Formoterol fumarate dihydrate 183814-30-4 C23H28N2O8
7H-DIBENZO[C,G]CARBAZOLE 7H-DIBENZO[C,G]CARBAZOLE 194-59-2 C20H13N
AFLATOXIN B2 AFLATOXIN B2 7220-81-7 C17H14O6
Fluphenazine decanoate Fluphenazine decanoate 5002-47-1 C32H44F3N3O2S
1-Isobutyl-4-piperidone 1-Isobutyl-4-piperidone 72544-16-2 C9H17NO
6-HYDROXYCHLORZOXAZONE 6-HYDROXYCHLORZOXAZONE 1750-45-4 C7H4ClNO3
Oxethazaine Oxethazaine 126-27-2 C28H41N3O3
VERRUCULOGEN VERRUCULOGEN 12771-72-1 C27H33N3O7
TRANS-NONACHLOR TRANS-NONACHLOR 39765-80-5 C10H5Cl9
Heptachlor- endo- epoxide(trans-,isomer A) Heptachlor- endo- epoxide(trans-,isomer A) 28044-83-9 C10H5Cl7O
GUANERAN GUANERAN 5581-52-2 C9H8N8O2S
Chloramphenicol sodium succinate Chloramphenicol sodium succinate 982-57-0 C15H15Cl2N2O8.Na
BROMOCHLOROACETIC ACID BROMOCHLOROACETIC ACID 5589-96-8 C2H2BrClO2
4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE 4-ETHOXYMETHYLENE-2-PHENYL-2-OXAZOLIN-5-ONE 15646-46-5 C12H11NO3
DOTHIEPIN HCL DOTHIEPIN HCL 897-15-4 C19H22ClNS
TRIETHYLTIN CHLORIDE TRIETHYLTIN CHLORIDE 994-31-0 C6H15ClSn
BENZATHINE PENICILLINE G TETRAHYDRATE BENZATHINE PENICILLINE G TETRAHYDRATE 41372-02-5 C32H38N4O4S
TRANS-4,4'-DIPHENYLSTILBENE TRANS-4,4'-DIPHENYLSTILBENE 2039-68-1 C26H20
4-(4-Chloro-benzyl)-2H-phthalazin-1-one 4-(4-Chloro-benzyl)-2H-phthalazin-1-one 53242-88-9 C15H11ClN2O
2,3-DINITROTOLUENE 2,3-DINITROTOLUENE 602-01-7 C7H6N2O4
Milbemycin oxime Milbemycin oxime 129496-10-2 2C32H45NO7.2C31H43NO7
2,5-PYRIDINEDICARBOXYLIC ACID DI-N-PROPYL ESTER 2,5-PYRIDINEDICARBOXYLIC ACID DI-N-PROPYL ESTER 136-45-8 C13H17NO4
SODIUM METATUNGSTATE SODIUM METATUNGSTATE 12141-67-2 NaO40W12(-5)
O-(2,3,4,5,6-PENTAFLUOROBENZYL)FORMALDOXIME O-(2,3,4,5,6-PENTAFLUOROBENZYL)FORMALDOXIME 86356-73-2 C8H4F5NO
M-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE M-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE 2880-05-9 C14H12N4O4
3-HYDROXY-P-BUTYROPHENETIDINE 3-HYDROXY-P-BUTYROPHENETIDINE 1083-57-4 C12H17NO3
LINOELAIDIC ACID LINOELAIDIC ACID 506-21-8 C18H32O2
DIGOXIGENIN DIGOXIGENIN 1672-46-4 C23H34O5
2,6-DIMETHYL-4-NITROSOPHENOL 2,6-DIMETHYL-4-NITROSOPHENOL 14818-35-0 C12H16O2
16-DOXYL-STEARIC ACID 16-DOXYL-STEARIC ACID 53034-38-1 C22H42NO4*
Zeranol Zeranol 26538-44-3 C18H26O5
SCHRADAN SCHRADAN 152-16-9 C8H24N4O3P2
DIBENZO(A,E)PYRENE DIBENZO(A,E)PYRENE 192-65-4 C24H14
4-Hydroxytolbutamide 4-Hydroxytolbutamide 5719-85-7 C12H18N2O4S
ALPRENOLOL HYDROCHLORIDE ALPRENOLOL HYDROCHLORIDE 13707-88-5 C15H24ClNO2
Cythioate Cythioate 115-93-5 C8H12NO5PS2
THIOTHIAMINE THIOTHIAMINE 299-35-4 C12H16N4OS2
3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE 3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE 10135-38-3 C8H15NO
OXYCODONE HYDROCHLORIDE OXYCODONE HYDROCHLORIDE 124-90-3 C18H22ClNO4
Methohexital Methohexital 151-83-7 C14H18N2O3
2-Benzhydrylsulphinylacetic acid 2-Benzhydrylsulphinylacetic acid 63547-24-0 C15H14O3S
2-Methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one-hydrochloridepropan-1-one-hydrochloride 2-Methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one-hydrochloridepropan-1-one-hydrochloride 186028-80-8 C11H14ClNO3
ALBENDAZOLE SULFONE ALBENDAZOLE SULFONE 75184-71-3 C12H15N3O4S
METHYL HENEICOSANOATE METHYL HENEICOSANOATE 6064-90-0 C22H44O2
4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] 27470-51-5 C24H26N2O6
ENTEROKINASE ENTEROKINASE 9014-74-8 NULL
O,P'-DDE O,P'-DDE 3424-82-6 C14H8Cl4
(+)-ISOMENTHOL (+)-ISOMENTHOL 23283-97-8 C10H20O
4-tert-Butyl-2-chlorophenol 4-tert-Butyl-2-chlorophenol 98-28-2 C10H13ClO
PAXILLINE PAXILLINE 57186-25-1 C27H33NO4
GAMMA-LINOLENIC ACID METHYL ESTER GAMMA-LINOLENIC ACID METHYL ESTER 16326-32-2 C19H32O2
CORTISOL 17-VALERATE CORTISOL 17-VALERATE 57524-89-7 C26H38O6
HYDROXYZINE PAMOATE HYDROXYZINE PAMOATE 10246-75-0 C44H43ClN2O8
SUNFLOWER SEED OIL SUNFLOWER SEED OIL 8001-21-6 NULL
1-(2-[4-Chlorophenoxy]acetyl)-4-(3,4-methylenedioxybenzyl)piperazine 1-(2-[4-Chlorophenoxy]acetyl)-4-(3,4-methylenedioxybenzyl)piperazine 34161-24-5 C20H21ClN2O4
(-)-TERPINEN-4-OL (-)-TERPINEN-4-OL 20126-76-5 C10H18O
O-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE O-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE 1773-44-0 C14H12N4O4
BENZALDEHYDE 2,4-DINITROPHENYLHYDRAZONE BENZALDEHYDE 2,4-DINITROPHENYLHYDRAZONE 1157-84-2 C13H10N4O4
5-Ethyl-2-(4-isopropyl-4-methyl-5-oxo-1H-imidazolin-2-yl)nicotinic acid 5-Ethyl-2-(4-isopropyl-4-methyl-5-oxo-1H-imidazolin-2-yl)nicotinic acid 81385-77-5 C32H24O3S
CHONDROITIN SULFATE B SODIUM SALT CHONDROITIN SULFATE B SODIUM SALT 54328-33-5 NULL
ETHYL METHYL KETONE 2,4-DINITROPHENYLHYDRAZONE ETHYL METHYL KETONE 2,4-DINITROPHENYLHYDRAZONE 958-60-1 C10H12N4O4
DIHYDROMETHYSTICIN DIHYDROMETHYSTICIN 19902-91-1 C15H16O5
2,4,5,6-TETRACHLORO-M-XYLENE 2,4,5,6-TETRACHLORO-M-XYLENE 877-09-8 C8H6Cl4
DIBENZO[B,DEF]CHRYSENE DIBENZO[B,DEF]CHRYSENE 189-64-0 C24H14
ALPHA,ALPHA'-BIS(4-HYDROXYPHENYL)-1,4-DIISOPROPYLBENZENE ALPHA,ALPHA'-BIS(4-HYDROXYPHENYL)-1,4-DIISOPROPYLBENZENE 2167-51-3 C24H26O2
N-NITROSOPIPERIDINE N-NITROSOPIPERIDINE 100-75-4 C5H10N2O
CIS-11-OCTADECENOIC ACID METHYL ESTER CIS-11-OCTADECENOIC ACID METHYL ESTER 1937-63-9 C19H36O2
Rilmenidine phosphate Rilmenidine phosphate 85409-38-7 C10H19N2O5P
2,4,6-TRICHLOROANISOLE 2,4,6-TRICHLOROANISOLE 87-40-1 C7H5Cl3O
ETHYLHYDROCUPREINE HYDROCHLORIDE ETHYLHYDROCUPREINE HYDROCHLORIDE 3413-58-9 C21H29ClN2O2
DIBENZO(A,I)PYRENE DIBENZO(A,I)PYRENE 191-30-0 C24H14
1(ALPHA) 25-DIHYDROXYVITAMIN D2* 1(ALPHA) 25-DIHYDROXYVITAMIN D2* 60133-18-8 C28H44O3
Demethyl tetrandrine Demethyl tetrandrine 33889-68-8 C37H40N2O6
DIBUTYL CHLORENDATE DIBUTYL CHLORENDATE 1770-80-5 C17H20Cl6O4
alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid 67118-31-4 C8H13NO3
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