CP-96021 hydrochloride

CP-96021 hydrochloride Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:CP-96021 hydrochloride
CAS:167011-22-5
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:CP-96021 hydrochloride
CAS:167011-22-5
Purity:>=95% Remarks:Please reach out to us for more information about custom solutions.
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:CP-96021 hydrochloride
CAS:167011-22-5
Package:50mg;1980USD|25mg;1520USD|100mg;2500USD
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:CP-96021 hydrochloride
CAS:167011-22-5
Package:50mg;1980USD|25mg;1520USD|100mg;2500USD
Company Name: RD International Technology Co., Limited  
Tel: 18024082417
Email: market@ubiochem.com
Products Intro: Product Name:CP-96021 hydrochloride
CAS:167011-22-5

CP-96021 hydrochloride manufacturers
CP-96021 hydrochloride Basic information
Product Name:CP-96021 hydrochloride
Synonyms:CP-96021 hydrochloride;CP96021 hydrochloride,CP 96021 hydrochloride
CAS:167011-22-5
MF:C29H22ClFN4OS
MW:529.03
EINECS:
Product Categories:
Mol File:167011-22-5.mol
CP-96021 hydrochloride Structure
CP-96021 hydrochloride Chemical Properties
Safety Information
MSDS Information
CP-96021 hydrochloride Usage And Synthesis
UsesCP-96021 hydrochloride is a balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Ki values of 34 nM and 37 nM, respectively[1].
in vivo

In vivo, CP-96021 inhibits iv LTD4- and iv PAF-induced bronchoconstriction in guinea pigs with ED50s of 0.46 and 0.16 mg/kg p.o. respectively. CP-96021 effectively blocks the combined airway obstructive effects of endogenously released PAF and LTD4 stimulated by aerosolized antigen challenge in guinea pigs with an ED50s of 1.8 mg/kg p.o[1].

IC 50LTC4: 34 nM (Ki); Platelet activating factor (PAF) receptor: 37 nM (Ki)
References[1] A. Marfat, et al. The discovery of CP-96,021 and CP-96,486, balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 1995, 5 (13): 1377-1382.
CP-96021 hydrochloride Preparation Products And Raw materials
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