- 2,5-Dibromopyrazine
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- $1.10
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2025-11-18
- CAS:23229-26-7
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons
- 2,5-Dibromopyrazine
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2022-01-27
- CAS:23229-26-7
- Min. Order: 1KG
- Purity: 97.4%
- Supply Ability: 100 tons
- 2,5-Dibromopyrazine
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2020-04-29
- CAS:23229-26-7
- Min. Order: 1KG
- Purity: 99.0%+
- Supply Ability: 800 tons
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| Product Name: | 2,5-Dibromopyrazine | | Synonyms: | 2,5-DIBROMOPYRAZINE;3,6-Dibromopyrazine, 2,5-Dibromo-1,4-diazine;2,5-bisbromopyrazine;PYRAZINE,2,5-DIBROMO;2,5-Dibromopyrazine>;2,5-Dibromopyrazine ISO 9001：2015 REACH;5-Dibromopyrazine;2,5-Dibromopyrazine 95% (GC) | | CAS: | 23229-26-7 | | MF: | C4H2Br2N2 | | MW: | 237.88 | | EINECS: | 805-812-6 | | Product Categories: | Halides;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Pyrazine | | Mol File: | 23229-26-7.mol |  |
| | 2,5-Dibromopyrazine Chemical Properties |
| Melting point | 45.0 to 49.0 °C | | Boiling point | 234.0±35.0 °C(Predicted) | | density | 2.197 | | Fp | 95℃ | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | powder to crystal | | pka | -4.28±0.10(Predicted) | | color | White to Orange to Green | | InChI | InChI=1S/C4H2Br2N2/c5-3-1-7-4(6)2-8-3/h1-2H | | InChIKey | KIYKHEOWZLJZSB-UHFFFAOYSA-N | | SMILES | C1(Br)=NC=C(Br)N=C1 | | CAS DataBase Reference | 23229-26-7 |
| Hazard Codes | Xi,Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26-36/37/39 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29339900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2,5-Dibromopyrazine Usage And Synthesis |
| Application | 2,5-Dibromopyrazine is a common organic synthon that can serve as a molecular skeleton in the synthesis of bioactive molecules. | | Synthesis | 5-bromopyrazin-2-amine (3 g, 17.241 mmol) and bromine (8.2 g, 51.729 mmol) were added to aq. HBr solution at -15° C. Aq. solution of sodium nitrite (2.97 g, 43.0103 mmol) was then added to the mixture over a period of 1 h at -10° C. keeping the internal temperature below 5° C. during addition and stirred for 1 h at 0° C. Progress of reaction was monitored by TLC. After reaction completion reaction mass neutralised with 40percent NaOH solution and extracted with diethyl ether. The organic layer was dried over sodium sulphate and concentrated under reduced pressure (below 30° C.) to yield 2,5-Dibromopyrazine (1 g, 24.4percent) as brown oil. | | References | [1] Patent: US2017/291910, 2017, A1. Location in patent: Paragraph 0592-0594
[2] Journal of the American Chemical Society, 1949, vol. 71, p. 2798
[3] Chemistry - A European Journal, 2010, vol. 16, # 19, p. 5645 - 5660
[4] Patent: WO2004/56369, 2004, A1. Location in patent: Page/Page column 24-25 |
| | 2,5-Dibromopyrazine Preparation Products And Raw materials |
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