| Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
|
| Tel: |
010-60605840 15801484223; |
| Email: |
psaitong@jm-bio.com |
| Products Intro: |
Product Name:TNP-351
CAS:125991-51-7
Package:100mg;250mg;500mg Remarks: 試劑級(jí)
|
TNP 351 manufacturers
- TNP-351
-
- $8350.00
-
2026-05-11
- CAS:125991-51-7
- Purity:
- Supply Ability: 10g
|
| | TNP 351 Basic information |
| Product Name: | TNP 351 | | Synonyms: | TNP 351;N-[4-[3-(2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)propyl]benzoyl]-L-glutamic acid;L-Glutamic acid, N-[4-[3-(2,4-diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)propyl]benzoyl]- | | CAS: | 125991-51-7 | | MF: | C21H24N6O5 | | MW: | 440.45 | | EINECS: | | | Product Categories: | | | Mol File: | 125991-51-7.mol |  |
| | TNP 351 Chemical Properties |
| | TNP 351 Usage And Synthesis |
| Uses | TNP-351 is an antifolate. TNP-351, a dihydrofolate reductase (DHFR) inhibitor, has potent antitumor activity against not only leukemia cells but also solid tumor cells in vitro and in vivo[1]. | | References | [1] F Itoh ,et al. Novel pyrrolo[2,3-d]pyrimidine Antifolate TNP-351: Cytotoxic Effect on Methotrexate-Resistant CCRF-CEM Cells and Inhibition of Transformylases of De Novo Purine Biosynthesis. Cancer Chemother Pharmacol. 1994;34(4):273-9. DOI:10.1007/BF00686032 |
| | TNP 351 Preparation Products And Raw materials |
|