- Propargyl-PEG4-Br
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2026-07-24
- CAS:1308299-09-3
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Propargyl-PEG4-bromide Basic information |
| Product Name: | Propargyl-PEG4-bromide | | Synonyms: | Propargyl-PEG4-bromide;Alkyne-PEG4-Br;PROPARGYL-PEG4-BR;3,6,9,12-Tetraoxapentadec-14-yne, 1-bromo-;Propargyl-PEG4-Br/3,6,9,12-Tetraoxapentadec-14-yne, 1-bromo-;3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]prop-1-yne;Alkeyn-PEG4-Br;1-Bromo-3,6,9,12-tetraoxapentadec-14-yne | | CAS: | 1308299-09-3 | | MF: | C11H19BrO4 | | MW: | 295.17 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1308299-09-3.mol |  |
| | Propargyl-PEG4-bromide Chemical Properties |
| Boiling point | 334.3±32.0 °C(Predicted) | | density | 1.269±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | form | Liquid | | color | Light yellow to yellow |
| | Propargyl-PEG4-bromide Usage And Synthesis |
| Description | Propargyl-PEG4-bromide is a crosslinker that can be used in copper catalyzed azide-alkyne Click Chemistry to form a stable triazole linkage with azides. The bromide (Br) acts as a good leaving group for nucleophilic substitution reactions. | | Uses | Propargyl-PEG4-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG4-Br is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | Non-cleavable Linker; PEGs | | References | [1] Suzanne AKERS-RODRIGUEZ, et al. Compositions and methods for the treatment of bacterial infections. WO2019126353A2. |
| | Propargyl-PEG4-bromide Preparation Products And Raw materials |
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