(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate

(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate Suppliers list
Company Name: BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Tel: +86-18600796368
Email: sales@sjar-tech.com
Products Intro: Product Name:Talazoparib Tosylate
CAS:1373431-65-2
Purity:More Than 99% Package:1g
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:Talazoparibtosylate
CAS:1373431-65-2
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
Email: factory@coreychem.com
Products Intro: Product Name:(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate
CAS:1373431-65-2
Purity:97%-99.9% Package:1KG;1USD
Company Name: ENBRIDGE PHARMTECH CO., LTD.
Tel: +8613812269233
Email: tinayang@enbridgepharm.com
Products Intro: Product Name:Talazoparib tosylate
CAS:1373431-65-2
Package:25KG
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Talazoparib tosylate；BMN 673ts
CAS:1373431-65-2
Package:10 mg；100 mg；2 mg；200 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate manufacturers

  • Talazoparib Tosylate
  • Talazoparib Tosylate pictures
  • 2026-06-12
  • CAS:1373431-65-2
  • Min. Order: 1g
  • Purity: More Than 99%
  • Supply Ability: 100kg/Month
(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate Basic information
Product Name:(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate
Synonyms:(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate;BMN-673 ts;BMN-673;BMN673;BMN 673;CS-2862;(8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido(4,3,2-de)phthalazin-3-one MONO(4-methylbenzenesulfonate);Talazoparib tosylate (BMN 673ts);BMN673; BMN673; BMN-673; L;(8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one 4-methylbenzenesulfonate
CAS:1373431-65-2
MF:C26H22F2N6O4S
MW:552.56
EINECS:
Product Categories:
Mol File:1373431-65-2.mol
(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate Structure
(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate Chemical Properties
Melting point >281°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Acetone (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form Solid
color Off-White to Pale Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate Usage And Synthesis
UsesTalazoparib Tosylate is Quinoline derivative used for treating non-small cell lung cancer.
in vivo

Talazoparib is readily orally bioavailable, with more than 40% absolute oral bioavailability in rats when dosed in carboxylmethyl cellulose. Oral administration of Talazoparib elicits remarkable antitumor activity; xenografted tumors that carry defects in DNA repair due to BRCA mutations or PTEN deficiency are profoundly sensitive to oral Talazoparib treatment at well-tolerated doses in mice. Synergistic or additive antitumor effects are also found when Talazoparib is combined with temozolomide, SN38, or platinum drugs[1].

(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate Preparation Products And Raw materials
Tag:(8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one tosylate(1373431-65-2) Related Product Information
Talampanel