- 5-Bromo-M-Xylene
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- $5.00
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2026-05-28
- CAS:556-96-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000kg
- 5-Bromo-m-xylene
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-
2026-03-31
- CAS:556-96-7
- Min. Order: 1000g
- Purity: 99%
- Supply Ability: 20tons
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| | 5-Bromo-m-xylene Basic information |
| | 5-Bromo-m-xylene Chemical Properties |
| Melting point | -20.49°C (estimate) | | Boiling point | 202-204 °C(lit.) | | density | 1.362 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.549(lit.) | | Fp | 189 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Miscible with tetrahydrofuran. | | form | Liquid | | color | Clear colorless to light yellow | | Specific Gravity | 1.362 | | BRN | 1926375 | | InChI | InChI=1S/C8H9Br/c1-6-3-7(2)5-8(9)4-6/h3-5H,1-2H3 | | InChIKey | LMFRTSBQRLSJHC-UHFFFAOYSA-N | | SMILES | C1(Br)=CC(C)=CC(C)=C1 | | CAS DataBase Reference | 556-96-7(CAS DataBase Reference) | | NIST Chemistry Reference | Benzene, 1-bromo-3,5-dimethyl-(556-96-7) |
| | 5-Bromo-m-xylene Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | 1-Bromo-3,5-dimethylbenzene has been used in the synthesis of substituted 2,2′-bis(diphenylphosphanylmethyl)-1,1′-binaphthyl derivatives. | | Uses | 5-Bromo-m-xylene is used in the preparation of substituted 2,2'-bis(diphenylphosphanylmethyl)-1,1'-binaphthyl derivatives. It is also used to prepare o-tolyl-3,5-xylyl ether by reacting with o-cresol. Further, it is an organic building block used in the synthesis of various chemicals as well as in the preparation of tri-o-tolylphosphine. | | Uses | 5-Bromo-m-xylene has been used in the synthesis of substituted 2,2′-bis(diphenylphosphanylmethyl)-1,1′-binaphthyl derivatives. | | General Description | Palladium catalyzed carbon-oxygen coupling of 1-bromo-3,5-dimethylbenzene and o-cresol to potassium hydroxide to produce o-tolyl-3,5-xylyl ether has been reported. | | Synthesis | General procedure for the synthesis of 3,5-dimethylbromobenzene from 3,5-dimethylphenylboronic acid: KX (X = I, Br) (0.2 mmol), 3,5-dimethylphenylboronic acid (0.3 mmol), CuBr2 (4.5 mg, 10 mol%), 1,10-phenanthroline (7.2 mg, 20 mol%), and DMF (2 mL). The reaction mixture was stirred at 80 °C or 130 °C for the reaction. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was purified by rapid column chromatography on silica gel to afford the target product 3,5-dimethylbromobenzene. | | References | [1] Tetrahedron Letters, 2011, vol. 52, # 16, p. 1993 - 1995 |
| | 5-Bromo-m-xylene Preparation Products And Raw materials |
| Raw materials | 4-Bromo-2,6-dimethylaniline-->3,5-Dimethylphenylboronic acid-->o-Phenanthroline-->Oxygen-->Potassium bromide-->N,N-Dimethylformamide-->Cupric bromide | | Preparation Products | (S)-(-)-7,7'-BIS[DI(3,5-DIMETHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->2-Dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl-->TRI-M-TOLYLPHOSPHINE-->TRI-P-TOLYLPHOSPHINE-->(XYL)2P(O)H-->3,5-Dimethylbenzaldehyde-->1-Iodo-3,5-dimethylbenzene-->3-(aminomethyl)-5-bromobenzonitrile-->3,3',5,5'-TETRAMETHYLBIPHENYL-->3-Bromo-5-cyanobenzyl bromide-->METHYL 3,5-DIMETHYLBENZOATE-->BIS(3,5-DIMETHYLPHENYL)PHOSPHINE-->3-bromo-5-methylbenzoic acid-->3,5-Dimethylphenylhydrazine hydrochloride-->1-ETHYNYL-3,5-DIMETHYL-BENZENE-->2-Chloro-3',5'-dimethylbenzophenone |
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