鹽酸地托咪定
| 中文名稱 | 鹽酸地托咪定 |
|---|---|
| 中文同義詞 | 4-[(2,3-二甲基苯基)甲基]-1H-咪唑鹽酸鹽;鹽酸地托咪定;鹽酸地托咪啶;鹽酸地拖嘧啶;地托咪定鹽酸鹽;地托咪啶;地托米定鹽酸鹽;4-(2,3-二甲基芐基)-1H-咪唑 鹽酸鹽 |
| 英文名稱 | Detomidine hydrochloride |
| 英文同義詞 | 5-[(2,3-DiMethylphenyl)Methyl]-1H-iMidazole Hydrochloride;DoMosedan;DorMosedan;MPV 253AII;DetoMidine hydrochloride (DorMosedan);API017;DTMT.HCl;1H-IMidazole,5-[(2,3-diMethylphenyl)Methyl]-, hydrochloride (1:1) |
| CAS號(hào) | 90038-01-0 |
| 分子式 | C12H15ClN2 |
| 分子量 | 222.7139 |
| EINECS號(hào) | 202-303-5 |
| 相關(guān)類別 | 神經(jīng)信號(hào);小分子抑制劑，天然產(chǎn)物;醫(yī)藥原料藥;定制化學(xué)品;原料藥;醫(yī)用原料;標(biāo)準(zhǔn)品;醫(yī)藥原料;APIs;API;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors;雜質(zhì)對(duì)照品;化學(xué)試劑;日用化學(xué)品;對(duì)照品-雜質(zhì)對(duì)照品 |
| Mol文件 | 90038-01-0.mol |
| 結(jié)構(gòu)式 |  |
鹽酸地托咪定 性質(zhì)
| 熔點(diǎn) | 160°C |
|---|---|
| 儲(chǔ)存條件 | Sealed in dry,Room Temperature |
| 溶解度 | 可溶于DMSO（少許）、甲醇（少許） |
| 形態(tài) | 固體 |
| 顏色 | 白色至類白色 |
| 主要應(yīng)用 | 藥物（小分子） |
| InChI | InChI=1S/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12;/h3-5,7-8H,6H2,1-2H3,(H,13,14);1H |
| InChI | 1S/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12;/h3-5,7-8H,6H2,1-2H3,(H,13,14);1H |
| InChIKey | OIWRDXKNDCJZSM-UHFFFAOYSA-N |
| SMILES | [Cl-].[nH]1cncc1Cc2c(c(ccc2)C)C.[H+] |
| SMILES | C1(C=CC=C(C)C=1C)CC1N=CNC=1.Cl |
Detomidine HCl可產(chǎn)生鎮(zhèn)靜和鎮(zhèn)痛作用，這種作用具有劑量依賴性，通過激活α2兒茶酚胺受體來調(diào)節(jié)。
| Target | Value |
| Adrenergic Receptor |
Currently, detomidine is only licenced for use in horses. Detomidine is a sedative with analgesic properties. α2-adrenergic agonists produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action.
安全信息
| 危險(xiǎn)品運(yùn)輸編號(hào) | UN 2811 6.1 / PGIII |
|---|---|
| WGK Germany | WGK 3 |
| RTECS號(hào) | NI5160000 |
| 海關(guān)編碼 | 2933.29.4300 |
| 存儲(chǔ)類別 | 11 - 可燃固體 |
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2026/07/06 | S2092 | 鹽酸地托咪定 Detomidine HCl | 90038-01-0 | 10mg | 904.82元 |
| 2026/06/06 | D4331 | 地托咪定鹽酸鹽 Detomidine Hydrochloride | 90038-01-0 | 200mg | 470元 |