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Postion:Product Catalog >API>Specialty drugs>Dermatology drugs>8-Methoxypsoralen
8-Methoxypsoralen
  • 8-Methoxypsoralen

8-Methoxypsoralen

Price $127
Package 10g
Min. Order: 10g
Supply Ability: 100KG
Update Time: 2021-11-02

Product Details

Product Name: 8-Methoxypsoralen CAS No.: 298-81-7
Min. Order: 10g Purity: 99%
Supply Ability: 100KG Release date: 2021/11/02

Product Name: 8-Methoxypsoralen

Synonyms: 2-g)(1)benzopyran-7-one,9-methoxy-7h-furo(;2-g][1]benzopyran-7-one,9-methoxy-7h-furo[;8-Methoxy-2',3',6,7-furocoumarin;8-methoxy-2,3,6,7-furocoumarin;8-Methoxy-4',5',6,7-furocoumarin;8-Methoxy-4',5':6,7-furocoumarin;8-methoxy-4,5,6,7-furocoumarin;8-methoxy-4,5:6,7-furocoumarin

CAS: 298-81-7

MF: C12H8O4

MW: 216.19

EINECS: 206-066-9


Description

8-methoxypsoralen (also known as methoxsalen) is a naturally occurring furocoumarin compound existing in several species of plants such as Psoralea corylifolia. It is a photoactive substance that can form DNA adducts upon UVA irradiation. It is a drug used for the treatment of psoriasis, eczema, vitiligo, and some kinds of cutaneous lymphomas associated with the exposure of skin to the UVA or light from lamps or sunlight. Its mechanism of action is through inhibiting the synthesis of the deoxyribonucleic acid (DNA). After the activation, it can preferentially bind to the guanine and cytosine molecules of DNA, further leading to the cross-linking of DNA, thus inhibiting the DNA synthesis. It can further inhibit the RNA and protein synthesis at high concentration. It is extracted from Ammi majus.


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