22-(4′-py)-JA NEW
| Price | Get Latest Price | |
| Package | 5mg | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: 22-(4′-py)-JA | CAS No.: 1178895-15-2 |
| Supply Ability: 10g | Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | 22-(4′-py)-JA |
| Description | 22-(4′-py)-JA, a semisynthetic derivative of junamycin A isolated from the Thai blue sponge (Xestospongia sp.), exhibits antimetastatic properties by inhibiting the AKT/mTOR/p70S6K signaling pathway. It also impedes tumor cell invasion and angiogenesis in human umbilical vein endothelial cells (HUVEC), while suppressing the expression of metalloproteinases (MMP-2 and MMP-9), hypoxia-inducible factor 1α (HIF-1α), and vascular endothelial growth factor (VEGF). Its potent anticancer activity is particularly noted against non-small cell lung cancer (NSCLC) [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Aceglutamide | Musk ketone | L-Leucine | Stearamide | Bisphenol A | Creatine monohydrate | Hyaluronic acid | Ethyl linoleate | L-Valine | Methyl eugenol | 2,3-Butanediol | Dihydromyricetin |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $123.00 |
VIP6Y
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TargetMol Chemicals Inc.
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2026-07-27 | |
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VIP4Y
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TargetMol Chemicals Inc.
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2026-04-20 | ||
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VIP3Y
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Xian confluore Biological Technology Co., Ltd.
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2025-06-07 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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