Febuxostat
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1G |
| Supply Ability: | 100KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: Febuxostat | CAS No.: 144060-53-7 |
| Min. Order: 1G | Purity: 98% |
| Supply Ability: 100KG | Release date: 2019/07/06 |
AD68
| Febuxostat Basic information |
| Indications and Usage Mechanisms of Action |
| Product Name: | Febuxostat |
| Synonyms: | Febuxostat (Uloric);FBX;Uloric;Febuxostat (TEI-6720);Febuxostat Tablets;FEBUXOSTAT API;Febuxostat (This product is unavailable in the U.S.);Febuxostat Tabletshehe |
| CAS: | 144060-53-7 |
| MF: | C16H16N2O3S |
| MW: | 316.37 |
| EINECS: | 1308068-626-2 |
| Product Categories: | zjh;API;Febuxostat;TRILIPIX;Other APIs;eterocycles;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 144060-53-7.mol |
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| Febuxostat Chemical Properties |
| Melting point | 238-239°(dec.) |
| storage temp. | Refrigerator |
| Merck | 14,3948 |
| CAS DataBase Reference | 144060-53-7(CAS DataBase Reference) |
| Safety Information |
| RTECS | XJ3675310 |
| MSDS Information |
| Febuxostat Usage And Synthesis |
| Indications and Usage | Febuxostat is a new generation xanthine oxidase inhibitor developed by Tejin Co. (Japan,) used clinically for for long-term treatment of hyperuicemia (gout,) a new and highly effective non-purine selective inhibitor of xanthine oxidase. It is not recommended for gout patients without hyperuricemia. |
| Mechanisms of Action | The production of uric acid in the body is related to purine metabolism. In the last step of the production, hypoxanthine produces xanthine through the action of xanthine oxidoreductase (XOR), finally producing uric acid. Inhibiting the activity of this enzyme can effectively reduce the production of uric acid. Xanthine oxidase is the main enzyme promoting uric acid production. Through highly selective inhibition of oxidized and reduced xanthine oxidase, Febuxostat can reduce synthesis of uric acid, decreasing its concentration and effectively treating gout . Through liver metabolism, Xanthine oxidase does not rely on renal excretion, so patients with moderate to severe liver and kidney dysfunction do not need to reduce dosages. Febuxostat is a non-purine XOR inhibitor, so it is very safe. |
| Chemical Properties | Crystalline Solid |
| Uses | antihyperlipidemic |
| Uses | Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout. |
| Uses | Febuxostat is primarily indicated in conditions like Gout, Hyperuricemia |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Zhengzhou High tech Zone, Henan Province, China
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com