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Postion:Product Catalog >4'-N-benzoylstaurosporine
4'-N-benzoylstaurosporine
  • 4'-N-benzoylstaurosporine
  • 4'-N-benzoylstaurosporine

4'-N-benzoylstaurosporine

Price $2
Package 1kg
Min. Order: 1kg
Supply Ability: 100kg
Update Time: 2019-07-06

Product Details

Product Name: 4'-N-benzoylstaurosporine CAS No.: 120685-11-2
Min. Order: 1kg Purity: 99%
Supply Ability: 100kg Release date: 2019/07/06
Product NUmber: : WM.562
 
 
4'-N-benzoylstaurosporine Basic information
Product Name: 4'-N-benzoylstaurosporine
Synonyms: 4'-N-benzoylstaurosporine;Midostaurin, Benzoylstaurosporine, 4'-N-Benzoylstaurosporine, CGP 41251;Benzamide, N-((9S,10R,11R,13R)-2,3,9,10,11,12-hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-J)(1,7)benzodiazonin-11-yl)-N-methyl-;Benzamide, N-(2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-1-oxo-8,12-epoxy-1H,8H-2,7B,12A-triazadibenzo(A,G)cyclonona(cde)trinden-10-yl)-N-methyl-, (8alpha,9beta,10beta,12alpha)-;Benzoylstaurosporine;Cgp 41 251;Cgp 41251;Cgp-41251
CAS: 120685-11-2
MF: C35H30N4O4
MW: 570.646
EINECS: 999-999-2
Product Categories: antibiotic
Mol File: 120685-11-2.mol
Article illustration
 
4'-N-benzoylstaurosporine Chemical Properties
Melting point  235-260℃
storage temp.  Store at 2-8
solubility  Soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml), 100% ethanol (2.5 mg/ml), and DMF (20 mg/ml).
 
Safety Information
Hazard Codes  T
Risk Statements  36/37/38
MSDS Information
 
 
4'-N-benzoylstaurosporine Usage And Synthesis
Uses Midostaurin was shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit.
Definition ChEBI: An organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine.
Biological Activity Broad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms ( α , β , γ ), PDFR β , VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Displays potent antitumor activity.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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